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2017 | OriginalPaper | Buchkapitel

A Novel Approach in Combination of 3D Gait Analysis Data for Aiding Clinical Decision-Making in Patients with Parkinson’s Disease

verfasst von : Ilaria Bortone, Gianpaolo Francesco Trotta, Antonio Brunetti, Giacomo Donato Cascarano, Claudio Loconsole, Nadia Agnello, Alberto Argentiero, Giuseppe Nicolardi, Antonio Frisoli, Vitoantonio Bevilacqua

Erschienen in: Intelligent Computing Theories and Application

Verlag: Springer International Publishing

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Abstract

The most common methods used by neurologist to evaluate Parkinson’s Disease (PD) patients are rating scales, that are affected by subjective and non-repeatable observations. Since several research studies have revealed that walking is a sensitive indicator
for the progression of PD. In this paper, we propose an innovative set of features derived from three-dimensional Gait Analysis in order to classify motor signs of motor impairment in PD and differentiate PD patients from healthy subjects or patients suffering from other neurological diseases. We consider kinematic data from Gait Analysis as Gait Variables Score (GVS), Gait Profile Score (GPS) and spatio-temporal data for all enrolled patients. We then carry out experiments evaluating the extracted features using an Artificial Neural Network (ANN) classifier. The obtained results are promising with the best classifier score accuracy equal to 95.05%.

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Literatur
1.
Zurück zum Zitat Twelves, D., Perkins, K.S., Counsell, C.: Systematic review of incidence studies of Parkinson’s disease. Mov. Disord. 18(1), 19–31 (2003)CrossRef Twelves, D., Perkins, K.S., Counsell, C.: Systematic review of incidence studies of Parkinson’s disease. Mov. Disord. 18(1), 19–31 (2003)CrossRef
2.
Zurück zum Zitat Bevilacqua, V., Nuzzolese, N., Barone, D., Pantaleo, M., Suma, M., D’Ambruoso, D., Volpe, A., Loconsole, C., Stroppa, F. Fall detection in indoor environment with kinect sensor. In: INISTA 2014 – Proceedings of the IEEE International Symposium on Innovations in Intelligent Systems and Applications, pp. 319–324 (2014). doi:10.1109/INISTA.2014.6873638 Bevilacqua, V., Nuzzolese, N., Barone, D., Pantaleo, M., Suma, M., D’Ambruoso, D., Volpe, A., Loconsole, C., Stroppa, F. Fall detection in indoor environment with kinect sensor. In: INISTA 2014 – Proceedings of the IEEE International Symposium on Innovations in Intelligent Systems and Applications, pp. 319–324 (2014). doi:10.​1109/​INISTA.​2014.​6873638
3.
Zurück zum Zitat Magdalinou, N., Morris, Huw R.: Clinical features and differential diagnosis of parkinson’s disease. In: Falup-Pecurariu, C., Ferreira, J., Martinez-Martin, P., Chaudhuri, K.R. (eds.) Movement Disorders Curricula, pp. 103–115. Springer, Vienna (2017). doi:10.1007/978-3-7091-1628-9_11 CrossRef Magdalinou, N., Morris, Huw R.: Clinical features and differential diagnosis of parkinson’s disease. In: Falup-Pecurariu, C., Ferreira, J., Martinez-Martin, P., Chaudhuri, K.R. (eds.) Movement Disorders Curricula, pp. 103–115. Springer, Vienna (2017). doi:10.​1007/​978-3-7091-1628-9_​11 CrossRef
4.
Zurück zum Zitat Song, J., Fisher, B.E., Petzinger, G., Wu, A., Gordon, J., Salem, G.J.: The relationships between the unified Parkinson’s disease rating scale and lower extremity functional performance in persons with early-stage Parkinson’s disease. Neurorehabilit. Neural Repair 23(7), 657–661 (2009)CrossRef Song, J., Fisher, B.E., Petzinger, G., Wu, A., Gordon, J., Salem, G.J.: The relationships between the unified Parkinson’s disease rating scale and lower extremity functional performance in persons with early-stage Parkinson’s disease. Neurorehabilit. Neural Repair 23(7), 657–661 (2009)CrossRef
5.
Zurück zum Zitat Patel, S., Chen, B.R., Mancinelli, C., Paganoni, S., Shih, L., Welsh, M., Dy, J., Bonato, P.: Longitudinal monitoring of patients with Parkinson’s disease via wearable sensor technology in the home setting. In: Engineering in Medicine and Biology Society, EMBC, 2011 Annual International Conference of the IEEE, pp. 1552–1555. IEEE (2011) Patel, S., Chen, B.R., Mancinelli, C., Paganoni, S., Shih, L., Welsh, M., Dy, J., Bonato, P.: Longitudinal monitoring of patients with Parkinson’s disease via wearable sensor technology in the home setting. In: Engineering in Medicine and Biology Society, EMBC, 2011 Annual International Conference of the IEEE, pp. 1552–1555. IEEE (2011)
6.
Zurück zum Zitat Esser, P., Dawes, H., Collett, J., Feltham, M.G., Howells, K.: Assessment of spatio–temporal gait parameters using inertial measurement units in neurological populations. Gait Posture 34(4), 558–560 (2011)CrossRef Esser, P., Dawes, H., Collett, J., Feltham, M.G., Howells, K.: Assessment of spatio–temporal gait parameters using inertial measurement units in neurological populations. Gait Posture 34(4), 558–560 (2011)CrossRef
7.
Zurück zum Zitat Morris, M.E., Huxham, F., McGinley, J., Dodd, K., Iansek, R.: The biomechanics and motor control of gait in Parkinson disease. Clin. Biomech. 16(6), 459–470 (2001)CrossRef Morris, M.E., Huxham, F., McGinley, J., Dodd, K., Iansek, R.: The biomechanics and motor control of gait in Parkinson disease. Clin. Biomech. 16(6), 459–470 (2001)CrossRef
8.
Zurück zum Zitat Blin, O., Ferrandez, A.M., Serratrice, G.: Quantitative analysis of gait in Parkinson patients: increased variability of stride length. J. Neurol. Sci. 98(1), 91–97 (1990)CrossRef Blin, O., Ferrandez, A.M., Serratrice, G.: Quantitative analysis of gait in Parkinson patients: increased variability of stride length. J. Neurol. Sci. 98(1), 91–97 (1990)CrossRef
9.
Zurück zum Zitat Lewis, G.N., Byblow, W.D., Walt, S.E.: Stride length regulation in Parkinson’s disease: the use of extrinsic, visual cues. Brain 123(10), 2077–2090 (2000)CrossRef Lewis, G.N., Byblow, W.D., Walt, S.E.: Stride length regulation in Parkinson’s disease: the use of extrinsic, visual cues. Brain 123(10), 2077–2090 (2000)CrossRef
10.
Zurück zum Zitat Bloem, B.R., Valkenburg, V.V., Slabbekoorn, M., Willemsen, M.D.: The Multiple Tasks Test: development and normal strategies. Gait Posture 14(3), 191202 (2001)CrossRef Bloem, B.R., Valkenburg, V.V., Slabbekoorn, M., Willemsen, M.D.: The Multiple Tasks Test: development and normal strategies. Gait Posture 14(3), 191202 (2001)CrossRef
11.
Zurück zum Zitat Morris, M., Iansek, R., McGinley, J., Matyas, T., Huxham, F.: Threedimensional gait biomechanics in Parkinson’s disease: Evidence for a centrally mediated amplitude regulation disorder. Mov. Disord. 20(1), 40–50 (2005)CrossRef Morris, M., Iansek, R., McGinley, J., Matyas, T., Huxham, F.: Threedimensional gait biomechanics in Parkinson’s disease: Evidence for a centrally mediated amplitude regulation disorder. Mov. Disord. 20(1), 40–50 (2005)CrossRef
12.
Zurück zum Zitat Delval, A., Salleron, J., Bourriez, J.L., Bleuse, S., Moreau, C., Krystkowiak, P., Defebvre, L., Devos, P., Duhamel, A.: Kinematic angular parameters in PD: reliability of joint angle curves and comparison with healthy subjects. Gait Posture 28(3), 495501 (2008)CrossRef Delval, A., Salleron, J., Bourriez, J.L., Bleuse, S., Moreau, C., Krystkowiak, P., Defebvre, L., Devos, P., Duhamel, A.: Kinematic angular parameters in PD: reliability of joint angle curves and comparison with healthy subjects. Gait Posture 28(3), 495501 (2008)CrossRef
13.
Zurück zum Zitat Davis, R.B., Ounpuu, S., Tyburski, D., Gage, J.R.: A gait analysis data collection and reduction technique. Hum. Mov. Sci. 10(5), 575–587 (1991)CrossRef Davis, R.B., Ounpuu, S., Tyburski, D., Gage, J.R.: A gait analysis data collection and reduction technique. Hum. Mov. Sci. 10(5), 575–587 (1991)CrossRef
14.
Zurück zum Zitat Baker, R., McGinley, J.L., Schwartz, M.H., Beynon, S., Rozumalski, A., Graham, H.K., Tirosh, O.: The gait profile score and movement analysis profile. Gait Posture 30(3), 265–269 (2009)CrossRef Baker, R., McGinley, J.L., Schwartz, M.H., Beynon, S., Rozumalski, A., Graham, H.K., Tirosh, O.: The gait profile score and movement analysis profile. Gait Posture 30(3), 265–269 (2009)CrossRef
15.
Zurück zum Zitat Schutte, L.M., Narayanan, U., Stout, J.L., Selber, P., Gage, J.R., Schwartz, M.H.: An index for quantifying deviations from normal gait. Gait Posture 11(1), 25–31 (2000)CrossRef Schutte, L.M., Narayanan, U., Stout, J.L., Selber, P., Gage, J.R., Schwartz, M.H.: An index for quantifying deviations from normal gait. Gait Posture 11(1), 25–31 (2000)CrossRef
16.
Zurück zum Zitat Baker, R., McGinley, J.L., Schwartz, M., Thomason, P., Rodda, J., Graham, H.K.: The minimal clinically important difference for the Gait Profile Score. Gait Posture 35(4), 612–615 (2012)CrossRef Baker, R., McGinley, J.L., Schwartz, M., Thomason, P., Rodda, J., Graham, H.K.: The minimal clinically important difference for the Gait Profile Score. Gait Posture 35(4), 612–615 (2012)CrossRef
17.
Zurück zum Zitat Mazurowski, M.A., Habas, P.A., Zurada, J.M., Lo, J.Y., Baker, J.A., Tourassi, G.D.: Training neural network classifiers for medical decision making: The effects of imbalanced datasets on classification performance. Neural Netw. 21(2), 427–436 (2008)CrossRef Mazurowski, M.A., Habas, P.A., Zurada, J.M., Lo, J.Y., Baker, J.A., Tourassi, G.D.: Training neural network classifiers for medical decision making: The effects of imbalanced datasets on classification performance. Neural Netw. 21(2), 427–436 (2008)CrossRef
18.
Zurück zum Zitat Bevilacqua, V., Mastronardi, G., Menolascina, F., Pannarale, P., Pedone, A.: A novel multi-objective genetic algorithm approach to artificial neural network topology optimization: the breast cancer classification problem. In: International Joint Conference on Neural Networks, IJCNN 2006, pp. 1958–1965. IEEE, July 2006 Bevilacqua, V., Mastronardi, G., Menolascina, F., Pannarale, P., Pedone, A.: A novel multi-objective genetic algorithm approach to artificial neural network topology optimization: the breast cancer classification problem. In: International Joint Conference on Neural Networks, IJCNN 2006, pp. 1958–1965. IEEE, July 2006
19.
Zurück zum Zitat Bevilacqua, V., Pacelli, V., Saladino, S.: A novel multi objective genetic algorithm for the portfolio optimization. In: Huang, D.-S., Gan, Y., Bevilacqua, V., Figueroa, J.C. (eds.) ICIC 2011. LNCS, vol. 6838, pp. 186–193. Springer, Heidelberg (2011). doi:10.1007/978-3-642-24728-6_25 CrossRef Bevilacqua, V., Pacelli, V., Saladino, S.: A novel multi objective genetic algorithm for the portfolio optimization. In: Huang, D.-S., Gan, Y., Bevilacqua, V., Figueroa, J.C. (eds.) ICIC 2011. LNCS, vol. 6838, pp. 186–193. Springer, Heidelberg (2011). doi:10.​1007/​978-3-642-24728-6_​25 CrossRef
20.
Zurück zum Zitat Bevilacqua, V., Tattoli, G., Buongiorno, D., Loconsole, C., Leonardis, D., Barsotti, M., Frisoli A., Bergamasco, M.: A novel BCI-SSVEP based approach for control of walking in virtual environment using a convolutional neural network. In: 2014 International Joint Conference on Neural Networks (IJCNN), pp. 4121–4128. IEEE, July 2014 Bevilacqua, V., Tattoli, G., Buongiorno, D., Loconsole, C., Leonardis, D., Barsotti, M., Frisoli A., Bergamasco, M.: A novel BCI-SSVEP based approach for control of walking in virtual environment using a convolutional neural network. In: 2014 International Joint Conference on Neural Networks (IJCNN), pp. 4121–4128. IEEE, July 2014
21.
Zurück zum Zitat Bevilacqua, V., Brunetti, A., Triggiani, M., Magaletti, D., Telegrafo, M., Moschetta, M.: An optimized feed-forward artificial neural network topology to support radiologists in breast lesions classification. In: Proceedings of the 2016 on Genetic and Evolutionary Computation Conference Companion, pp. 1385–1392. ACM, July 2016 Bevilacqua, V., Brunetti, A., Triggiani, M., Magaletti, D., Telegrafo, M., Moschetta, M.: An optimized feed-forward artificial neural network topology to support radiologists in breast lesions classification. In: Proceedings of the 2016 on Genetic and Evolutionary Computation Conference Companion, pp. 1385–1392. ACM, July 2016
22.
Zurück zum Zitat Bradley, A.P.: The use of the area under the ROC curve in the evaluation of machine learning algorithms. Pattern Recogn. 30(7), 1145–1159 (1997)CrossRef Bradley, A.P.: The use of the area under the ROC curve in the evaluation of machine learning algorithms. Pattern Recogn. 30(7), 1145–1159 (1997)CrossRef
Metadaten
Titel
A Novel Approach in Combination of 3D Gait Analysis Data for Aiding Clinical Decision-Making in Patients with Parkinson’s Disease
verfasst von
Ilaria Bortone
Gianpaolo Francesco Trotta
Antonio Brunetti
Giacomo Donato Cascarano
Claudio Loconsole
Nadia Agnello
Alberto Argentiero
Giuseppe Nicolardi
Antonio Frisoli
Vitoantonio Bevilacqua
Copyright-Jahr
2017
DOI
https://doi.org/10.1007/978-3-319-63312-1_44