2009 | OriginalPaper | Buchkapitel
A Quantitative Comparison of the Myocardial Fibre Orientation in the Rabbit as Determined by Histology and by Diffusion Tensor-MRI
verfasst von : Stephen H. Gilbert, Olivier Bernus, Arun V. Holden, Alan P. Benson
Erschienen in: Functional Imaging and Modeling of the Heart
Verlag: Springer Berlin Heidelberg
Aktivieren Sie unsere intelligente Suche, um passende Fachinhalte oder Patente zu finden.
Wählen Sie Textabschnitte aus um mit Künstlicher Intelligenz passenden Patente zu finden. powered by
Markieren Sie Textabschnitte, um KI-gestützt weitere passende Inhalte zu finden. powered by
Early models of rabbit cardiac fibre structure where from fitting histological fibre orientation onto finite element models. More recently models have been produced using DT-MRI. In a quantitative comparison of these models, in a selected equatorial slice the fibre helix angle has a transmural change of -111.8±30.8º (mean linear fit ± S.D.) in the histological data [H-1]), -92.4±54.5º in DT-MRI dataset [DTI-1] and -86.3±30.7º in DT-MRI dataset [DTI-2]. Variation is large due to outlier data near the RV posterior insertion, and is less when selected anatomical transmural locations are quantified; the lateral LV has a monotonic transmural change of H-1:-87.5±3.7º (mean linear fit ± S.E of slope); DTI-1: -84.8±2.2º; DTI-2:-77.7±2.5º. There is greater variation in the transmural change of the transverse angle than the helix angle (DTI-1, 4.6±83.0º (mean linear fit ± S.D.), pooled data). Limitations in the datasets from both methodologies are discussed in the light of this analysis.