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Erschienen in: Journal of Nanoparticle Research 9/2022

01.09.2022 | Research paper

Academic nanotechnology laboratories: investigating good practices and students’ health status

verfasst von: Soqrat Omari Shekaftik, Nafiseh Nasirzadeh, Tara Baba-Ahangar, Meysam Najaflou, Zahra Beigzadeh, Mohammad Javad Dehdashti, Hamid Noori, Reza Pourbabaki, Neda Naseri, Aysa Ghasemi Koozekonan, Zakia Rezaei

Erschienen in: Journal of Nanoparticle Research | Ausgabe 9/2022

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Abstract

Students working in nanotechnology laboratories could expose to nanomaterials during production, handling, and transportation of these materials. Studies have shown that nanomaterials have adverse effects on humans. So, this study was conducted to investigate the status of nanotechnology laboratories and also to examine students’ non-specific symptoms. This cross-sectional study was conducted in nanotechnology laboratories of 8 universities of medical sciences. Two questionnaires were used for data collection. A questionnaire was used to assess the status of laboratories and another to assess the non-specific symptoms of students. Finally, data were analyzed using SPSS 22.0. Results showed that only %33.7 of the laboratories had nanomaterials safety and health policy, while %63.6 of them reported the existence of general health and safety policy. Examination of the parameters affecting the exposure showed that in the studied laboratories, the ground for significant exposure to nanomaterials is provided. Study of transportation and storage of nanomaterials in the laboratories showed a relatively good situation. In terms of controls, condition was not favorable. The most reported symptoms among students were cutaneous, ocular, neurological, and respiratory symptoms, respectively. Comparing the status of the studied laboratories and the standards of nanotechnology laboratories, these laboratories are far from the ideal situation. Training the principles of working safely with nanomaterials, improving engineering controls, and providing appropriate PPEs for nanomaterials and using them properly, can effectively improve the laboratories, reduce exposure and reduce symptoms among the students.

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Literatur
3.
Zurück zum Zitat Mohammadian Y, Nasirzadeh N (2021) Toxicity risks of occupational exposure in 3D printing and bioprinting industries: a systematic review. Toxicol Ind Health 37:573–584 Mohammadian Y, Nasirzadeh N (2021) Toxicity risks of occupational exposure in 3D printing and bioprinting industries: a systematic review. Toxicol Ind Health 37:573–584
4.
Zurück zum Zitat Nasirzadeh N, Rasoulzadeh Y, Rezazadeh Azari M, Mohammadian Y (2020) Cellular toxicity of multi-walled carbon nanotubes on human lung cells. J Chem Health Risks 10:135–144 Nasirzadeh N, Rasoulzadeh Y, Rezazadeh Azari M, Mohammadian Y (2020) Cellular toxicity of multi-walled carbon nanotubes on human lung cells. J Chem Health Risks 10:135–144
8.
Zurück zum Zitat Omari Shekaftik S, Ashtarinezhad A, Yarahmadi R, Rasouli M, Soleimani M, Hosseini Shirazi F (2020) Relationship between chemical composition and physical State of used nanomaterials in nanotechnology companies with type and prevalance of symptoms of employees of these companies in Tehran. Iran Iran Occup Health 17:936–950 Omari Shekaftik S, Ashtarinezhad A, Yarahmadi R, Rasouli M, Soleimani M, Hosseini Shirazi F (2020) Relationship between chemical composition and physical State of used nanomaterials in nanotechnology companies with type and prevalance of symptoms of employees of these companies in Tehran. Iran Iran Occup Health 17:936–950
9.
Zurück zum Zitat Nasirzadeh N, Azari MR, Rasoulzadeh Y, Mohammadian Y (2019) An assessment of the cytotoxic effects of graphene nanoparticles on the epithelial cells of the human lung. Toxicol Indus Health 35:79–87 Nasirzadeh N, Azari MR, Rasoulzadeh Y, Mohammadian Y (2019) An assessment of the cytotoxic effects of graphene nanoparticles on the epithelial cells of the human lung. Toxicol Indus Health 35:79–87
10.
Zurück zum Zitat Rafieepour A, Azari MR, Jaktaji JP, Khodagholi F, Peirovi H, Mehrabi Y, Mohammadian Y (2021) The effect of particle size on the cytotoxicity of amorphous silicon dioxide: an in vitro toxicological study. Asian Pacific J Cancer Prevention: APJCP 22:325 Rafieepour A, Azari MR, Jaktaji JP, Khodagholi F, Peirovi H, Mehrabi Y, Mohammadian Y (2021) The effect of particle size on the cytotoxicity of amorphous silicon dioxide: an in vitro toxicological study. Asian Pacific J Cancer Prevention: APJCP 22:325
11.
Zurück zum Zitat Sengul AB, Asmatulu E (2020) Toxicity of metal and metal oxide nanoparticles: a review. Environ Chem Lett 18:1659–1683 Sengul AB, Asmatulu E (2020) Toxicity of metal and metal oxide nanoparticles: a review. Environ Chem Lett 18:1659–1683
12.
Zurück zum Zitat Utembe W, Tlotleng N, Kamng'ona A (2022) A systematic review on the effects of nanomaterials on gut microbiota. Curr Res Microb Sci:100118 Utembe W, Tlotleng N, Kamng'ona A (2022) A systematic review on the effects of nanomaterials on gut microbiota. Curr Res Microb Sci:100118
13.
Zurück zum Zitat Omari Shekaftik S, Nasirzadeh N (2021) 8-Hydroxy-2′-deoxyguanosine (8-OHdG) as a biomarker of oxidative DNA damage induced by occupational exposure to nanomaterials: a systematic review. Nanotoxicology 15:850–864 Omari Shekaftik S, Nasirzadeh N (2021) 8-Hydroxy-2′-deoxyguanosine (8-OHdG) as a biomarker of oxidative DNA damage induced by occupational exposure to nanomaterials: a systematic review. Nanotoxicology 15:850–864
14.
Zurück zum Zitat Alsaleh NB, Brown JM (2020) Engineered nanomaterials and type I allergic hypersensitivity reactions. Front Immunol 11:222 Alsaleh NB, Brown JM (2020) Engineered nanomaterials and type I allergic hypersensitivity reactions. Front Immunol 11:222
15.
Zurück zum Zitat Calderón-Gonzalez R et al (2016) Pregnancy vaccination with gold glyco-nanoparticles carrying Listeria monocytogenes peptides protects against listeriosis and brain-and cutaneous-associated morbidities. Nanomaterials 6:151 Calderón-Gonzalez R et al (2016) Pregnancy vaccination with gold glyco-nanoparticles carrying Listeria monocytogenes peptides protects against listeriosis and brain-and cutaneous-associated morbidities. Nanomaterials 6:151
16.
Zurück zum Zitat Meldrum K, Guo C, Marczylo EL, Gant TW, Smith R, Leonard MO (2017) Mechanistic insight into the impact of nanomaterials on asthma and allergic airway disease. Part Fibre Toxicol 14:1–35 Meldrum K, Guo C, Marczylo EL, Gant TW, Smith R, Leonard MO (2017) Mechanistic insight into the impact of nanomaterials on asthma and allergic airway disease. Part Fibre Toxicol 14:1–35
17.
18.
Zurück zum Zitat Omari Shekaftik S, Nasirzadeh N (2021) Iranian National Standards regarding safety, health and environmental aspects of nanotechnology: a review. J Occup Hyg Eng 8:1–8 Omari Shekaftik S, Nasirzadeh N (2021) Iranian National Standards regarding safety, health and environmental aspects of nanotechnology: a review. J Occup Hyg Eng 8:1–8
20.
Zurück zum Zitat Omari Shekaftik S, Mohammadi S, Zareipour M, Haghighi Asl A, Ahmadi Kanrash F, Soltani Gerdefaramarzi R (2021) Design and validation of a tool to assess the safety principles of working with nanomaterials in nanotechnology laboratories. SSUJ 13:38–47 Omari Shekaftik S, Mohammadi S, Zareipour M, Haghighi Asl A, Ahmadi Kanrash F, Soltani Gerdefaramarzi R (2021) Design and validation of a tool to assess the safety principles of working with nanomaterials in nanotechnology laboratories. SSUJ 13:38–47
21.
Zurück zum Zitat Demou E, Stark WJ, Hellweg S (2009) Particle emission and exposure during nanoparticle synthesis in research laboratories. Ann Occup Hyg 53:829–838 Demou E, Stark WJ, Hellweg S (2009) Particle emission and exposure during nanoparticle synthesis in research laboratories. Ann Occup Hyg 53:829–838
22.
Zurück zum Zitat Iavicoli I, Fontana L, Pingue P, Todea AM, Asbach CJSoTTE (2018) Assessment of occupational exposure to engineered nanomaterials in research laboratories using personal monitors 627:689–702 Iavicoli I, Fontana L, Pingue P, Todea AM, Asbach CJSoTTE (2018) Assessment of occupational exposure to engineered nanomaterials in research laboratories using personal monitors 627:689–702
24.
Zurück zum Zitat Zhang C, Zhang J, Wang G (2014) Current safety practices in nano-research laboratories in China. J Nanosci Nanotechnol 14:4700–4705 Zhang C, Zhang J, Wang G (2014) Current safety practices in nano-research laboratories in China. J Nanosci Nanotechnol 14:4700–4705
25.
Zurück zum Zitat CKMNT (2012) Guidelines and best practices for safe handling of nanomaterials in research laboratories and industries. India CKMNT (2012) Guidelines and best practices for safe handling of nanomaterials in research laboratories and industries. India
26.
Zurück zum Zitat Gibbs L, Lamba F, Stoxkmeier B, Kojola W (2012) General safe practices for working with engineered nanomaterials in research laboratories National Institute for Occupational Safety and Health (NIOSH) Gibbs L, Lamba F, Stoxkmeier B, Kojola W (2012) General safe practices for working with engineered nanomaterials in research laboratories National Institute for Occupational Safety and Health (NIOSH)
27.
Zurück zum Zitat R.T.M. Cornelissen MS-L, M.B.H.J. Vervoort and D. Hoeneveld (2014) Use of engineered nanomaterials in Dutch academic research settings – Part B: Good Practices. Hague, Netherlands R.T.M. Cornelissen MS-L, M.B.H.J. Vervoort and D. Hoeneveld (2014) Use of engineered nanomaterials in Dutch academic research settings – Part B: Good Practices. Hague, Netherlands
29.
Zurück zum Zitat Iavicoli I, Leso V, Fontana L (2019) Nanoparticle exposure in research laboratories. Italian J Occup Med Ergon 41:349–353 Iavicoli I, Leso V, Fontana L (2019) Nanoparticle exposure in research laboratories. Italian J Occup Med Ergon 41:349–353
31.
Zurück zum Zitat Etemadi M, Mahdzir AM (2021) Nanotechnology in Malaysia: a qualitative study about the current occupational health and safety issues. Psychol Educ 58:4727–4740 Etemadi M, Mahdzir AM (2021) Nanotechnology in Malaysia: a qualitative study about the current occupational health and safety issues. Psychol Educ 58:4727–4740
32.
Zurück zum Zitat Zhang C, Zhang J, Wang G (2014) Current safety practices in nano-research laboratories in china. J Nanosci Nanotechnol 14:4700–4705 Zhang C, Zhang J, Wang G (2014) Current safety practices in nano-research laboratories in china. J Nanosci Nanotechnol 14:4700–4705
33.
Zurück zum Zitat Asbach C et al (2017) Review of measurement techniques and methods for assessing personal exposure to airborne nanomaterials in workplaces 603:793-806 Asbach C et al (2017) Review of measurement techniques and methods for assessing personal exposure to airborne nanomaterials in workplaces 603:793-806
35.
Zurück zum Zitat Omari Shekaftik S, Nasirzadeh N (2021) Iranian National Standards regarding safety, health and environmental aspects of nanotechnology: a review umsha-johe 8:1–13 Omari Shekaftik S, Nasirzadeh N (2021) Iranian National Standards regarding safety, health and environmental aspects of nanotechnology: a review umsha-johe 8:1–13
36.
Zurück zum Zitat Tsai C-J, Pui DY (2009) Recent advances and new challenges of occupational and environmental health of nanotechnology. J Nanopart Res 11:1–4 Tsai C-J, Pui DY (2009) Recent advances and new challenges of occupational and environmental health of nanotechnology. J Nanopart Res 11:1–4
37.
Zurück zum Zitat Golbabai F, Haydarnzhad N, Sharfi K, Shaahamdi F, Hanifi SM, Harati B (2015) Occupational exposure risk assessment of engineered nanomaterial’s by CB nano tool in a nano, research laboratory. Tech J Eng Appl Sci 5:133–138 Golbabai F, Haydarnzhad N, Sharfi K, Shaahamdi F, Hanifi SM, Harati B (2015) Occupational exposure risk assessment of engineered nanomaterial’s by CB nano tool in a nano, research laboratory. Tech J Eng Appl Sci 5:133–138
39.
Zurück zum Zitat Sousa M, Arezes P, Silva F (2021) Occupational exposure to incidental nanoparticles: a review on control banding. In: J Physics 1:012008 Sousa M, Arezes P, Silva F (2021) Occupational exposure to incidental nanoparticles: a review on control banding. In: J Physics 1:012008
41.
Zurück zum Zitat NS M (2014) Occupational health and safety training: knowledge, attitude and practice among technical education students. Egypt J Occup Med 38:153–165 NS M (2014) Occupational health and safety training: knowledge, attitude and practice among technical education students. Egypt J Occup Med 38:153–165
42.
Zurück zum Zitat Díaz-Soler BM, López-Alonso M, Martínez-Aires MD (2017) Nanosafety practices: results from a national survey at research facilities. J Nanopart Res 19:169 Díaz-Soler BM, López-Alonso M, Martínez-Aires MD (2017) Nanosafety practices: results from a national survey at research facilities. J Nanopart Res 19:169
43.
Zurück zum Zitat Freeland J et al (2016) Working safely with nanomaterials in research & development, 2 edn. The UK NanoSafety Group (UKNSG) Freeland J et al (2016) Working safely with nanomaterials in research & development, 2 edn. The UK NanoSafety Group (UKNSG)
44.
Zurück zum Zitat Vinches L, Testori N, Dolez P, Perron G, Wilkinson KJ, Hallé SJNM (2013) Experimental evaluation of the penetration of TiO2 nanoparticles through protective clothing and gloves under conditions simulating occupational use 2:1–15 Vinches L, Testori N, Dolez P, Perron G, Wilkinson KJ, Hallé SJNM (2013) Experimental evaluation of the penetration of TiO2 nanoparticles through protective clothing and gloves under conditions simulating occupational use 2:1–15
45.
Zurück zum Zitat Vinches L, Hallé S, Peyrot C, Wilkinson KJJIJoT, Nanotechnology A (2014) Which gloves are efficient to protect against titanium dioxide nanoparticles in work conditions? 2:24–29 Vinches L, Hallé S, Peyrot C, Wilkinson KJJIJoT, Nanotechnology A (2014) Which gloves are efficient to protect against titanium dioxide nanoparticles in work conditions? 2:24–29
46.
Zurück zum Zitat Vinches L, Hallé SJJoO, Hygiene E (2017) Resistance of Type 5 chemical protective clothing against nanometric airborne particles: behavior of seams and zipper 14:939–946 Vinches L, Hallé SJJoO, Hygiene E (2017) Resistance of Type 5 chemical protective clothing against nanometric airborne particles: behavior of seams and zipper 14:939–946
47.
Zurück zum Zitat ISIRI (2015) Nano technology - Health and safety in nano occupational settings - Code of Practices. Institute of Standards and Industrial Research of Iran, Tehran, Iran ISIRI (2015) Nano technology - Health and safety in nano occupational settings - Code of Practices. Institute of Standards and Industrial Research of Iran, Tehran, Iran
48.
Zurück zum Zitat WHO Guidelines Approved by the Guidelines Review Committee (2017). In: WHO guidelines on protecting workers from potential risks of manufactured nanomaterials. World Health Organization(c) World Health Organization 2017., Geneva WHO Guidelines Approved by the Guidelines Review Committee (2017). In: WHO guidelines on protecting workers from potential risks of manufactured nanomaterials. World Health Organization(c) World Health Organization 2017., Geneva
50.
Zurück zum Zitat Larese Filon F (2017) Skin exposure to nanoparticles and possible sensitization risk. In: Allergy and immunotoxicology in occupational health. Springer, pp 143–152 Larese Filon F (2017) Skin exposure to nanoparticles and possible sensitization risk. In: Allergy and immunotoxicology in occupational health. Springer, pp 143–152
51.
Zurück zum Zitat Bae J-S et al (2022) Particulate matter exposure aggravates IL-17-induced eye and nose inflammation in an OVA/Poly (I: C) mouse model. Allergy, Asthma Immunol Res 14:59 Bae J-S et al (2022) Particulate matter exposure aggravates IL-17-induced eye and nose inflammation in an OVA/Poly (I: C) mouse model. Allergy, Asthma Immunol Res 14:59
52.
Zurück zum Zitat Zhu S, Gong L, Li Y, Xu H, Gu Z, Zhao Y (2019) Safety assessment of nanomaterials to eyes: an important but neglected issue. Adv Sci 6:1802289 Zhu S, Gong L, Li Y, Xu H, Gu Z, Zhao Y (2019) Safety assessment of nanomaterials to eyes: an important but neglected issue. Adv Sci 6:1802289
53.
Zurück zum Zitat Simkó M, Mattsson M-O (2010) Risks from accidental exposures to engineered nanoparticles and neurological health effects: a critical review. Part Fibre Toxicol 7:1–15 Simkó M, Mattsson M-O (2010) Risks from accidental exposures to engineered nanoparticles and neurological health effects: a critical review. Part Fibre Toxicol 7:1–15
54.
Zurück zum Zitat Garcia-Garcia E et al (2005) A relevant in vitro rat model for the evaluation of blood-brain barrier translocation of nanoparticles. Cell Mol Life Sci 62:1400–1408 Garcia-Garcia E et al (2005) A relevant in vitro rat model for the evaluation of blood-brain barrier translocation of nanoparticles. Cell Mol Life Sci 62:1400–1408
55.
Zurück zum Zitat Nitzsche A, Jung J, Pfaff H, Driller E (2013) Employees’ negative and positive work–home interaction and their association with depressive symptoms. Am J Ind Med 56:590–598 Nitzsche A, Jung J, Pfaff H, Driller E (2013) Employees’ negative and positive work–home interaction and their association with depressive symptoms. Am J Ind Med 56:590–598
56.
Zurück zum Zitat Lund T et al (2011) The influence of ligand organization on the rate of uptake of gold nanoparticles by colorectal cancer cells. Biomaterials 32:9776–9784 Lund T et al (2011) The influence of ligand organization on the rate of uptake of gold nanoparticles by colorectal cancer cells. Biomaterials 32:9776–9784
57.
Zurück zum Zitat Shaffer RE, Rengasamy S (2009) Respiratory protection against airborne nanoparticles: a review. J Nanopart Res 11:1661–1672 Shaffer RE, Rengasamy S (2009) Respiratory protection against airborne nanoparticles: a review. J Nanopart Res 11:1661–1672
58.
Zurück zum Zitat Nazarenko Y, Zhen H, Han T, Lioy PJ, Mainelis G (2012) Nanomaterial inhalation exposure from nanotechnology-based cosmetic powders: a quantitative assessment. J Nanopart Res 14:1–14 Nazarenko Y, Zhen H, Han T, Lioy PJ, Mainelis G (2012) Nanomaterial inhalation exposure from nanotechnology-based cosmetic powders: a quantitative assessment. J Nanopart Res 14:1–14
59.
Zurück zum Zitat Schinwald A, Murphy FA, Jones A, MacNee W, Donaldson K (2012) Graphene-based nanoplatelets: a new risk to the respiratory system as a consequence of their unusual aerodynamic properties. ACS Nano 6:736–746 Schinwald A, Murphy FA, Jones A, MacNee W, Donaldson K (2012) Graphene-based nanoplatelets: a new risk to the respiratory system as a consequence of their unusual aerodynamic properties. ACS Nano 6:736–746
60.
Zurück zum Zitat Oberdörster G, Oberdörster E, Oberdörster J (2005) Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles. Environ Health Perspect 113:823–839 Oberdörster G, Oberdörster E, Oberdörster J (2005) Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles. Environ Health Perspect 113:823–839
61.
Zurück zum Zitat Cena L, Chisholm W, Keane M, Chen B (2015) A field study on the respiratory deposition of the nano-sized fraction of mild and stainless steel welding fume metals. J Occup Environ Hyg 12:721–728 Cena L, Chisholm W, Keane M, Chen B (2015) A field study on the respiratory deposition of the nano-sized fraction of mild and stainless steel welding fume metals. J Occup Environ Hyg 12:721–728
62.
Zurück zum Zitat Lee MB, Greig JD (2010) A review of gastrointestinal outbreaks in schools: effective infection control interventions. J Sch Health 80:588–598 Lee MB, Greig JD (2010) A review of gastrointestinal outbreaks in schools: effective infection control interventions. J Sch Health 80:588–598
Metadaten
Titel
Academic nanotechnology laboratories: investigating good practices and students’ health status
verfasst von
Soqrat Omari Shekaftik
Nafiseh Nasirzadeh
Tara Baba-Ahangar
Meysam Najaflou
Zahra Beigzadeh
Mohammad Javad Dehdashti
Hamid Noori
Reza Pourbabaki
Neda Naseri
Aysa Ghasemi Koozekonan
Zakia Rezaei
Publikationsdatum
01.09.2022
Verlag
Springer Netherlands
Erschienen in
Journal of Nanoparticle Research / Ausgabe 9/2022
Print ISSN: 1388-0764
Elektronische ISSN: 1572-896X
DOI
https://doi.org/10.1007/s11051-022-05548-7

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