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2018 | Buch

Advances in Functional Micro-/Nanoimaging Probes

herausgegeben von: Zhe Liu

Verlag: Springer Singapore

Buchreihe : Engineering Materials

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Über dieses Buch

This book highlights the latest advances in functional micro/nano imaging probes and their applications for biomedical imaging and therapy. Given the rapid emergence of transdisciplinary research and applications in materials, chemical probes and translational medicine in recent years, scientists in these areas are expected to keep up to date on the latest technologies and advances to promote comprehensive innovations. Addressing this need, the book presents recently introduced features, emerging techniques, and new strategies, complemented by detailed illustrations. Covering the status quo and offering an outlook on the future, it benefits all readers with an interest in functional materials, especially micro/nano imaging materials for biomedical imaging applications, providing them with both vital updates and inspiration for their own research.

Inhaltsverzeichnis

Frontmatter
Chapter 1. Functional Micro-/Nanomaterials for Imaging Technology
Abstract
Functional micro-/nanomaterials, in particular, micro-/nanoimaging probes, have emerged as a hot topic in terms of both basic research and biomedical applications. More importantly, innovations and clinical translations of advanced imaging probes have substantially revolutionalized diagnostic techniques and therapy strategies addressing critical diseases. Therefore, this chapter presents a comprehensive description of the development history of biomedical imaging technology over the past decades and discusses various types of imaging probes corresponding to versatile imaging modalities.
Waner Chen, Wei Ma, Chunpeng Zou, Yan Yang, Gaoyi Yang, Li Liu, Zhe Liu
Chapter 2. Design, Fabrication, and Modification Protocols of Functional Micro-/Nanoimaging Probes
Abstract
The biosafety of micro-/nanoimaging probes is one of the most important elements that should be taken into consideration before their design and fabrication. In order to endow them specificity to lesions and bioavailability in vivo, targeting biomolecules, optimized biodistribution, and acceptable biocompatibility need to be introduced. These prerequisites ensure their behavior in the body and pave the way for their ultimate medical applications in humans, which should be pursued throughout the development of molecular imaging probes.
Doudou Wang, Li Liu, Wei Ma, Daren Liu, Qiuming Su, Xuemei Gu, Gaoyi Yang, Zhe Liu
Chapter 3. Biomedical Applications of Functional Micro-/Nanoimaging Probes
Abstract
As traditional molecular imaging modalities, the nature and physical fundamentals of MRI, US, OI, radionuclide-based PET/SPECT imaging, X-ray, and CT are elucidated in this chapter. The philosophy for the design, fabrication, and application of representative imaging probes are also described. Meanwhile, advanced imaging modalities and hybrid imaging probes for both clinical and basic study uses are also introduced to present a clear understanding to a broad and interdisciplinary readership especially at the frontiers of molecular imaging research.
Fangfang Yu, Shunlong Xu, Xianwei Ni, Jinmin Ye, Yueyue Cheng, Pengfei Wang, Beibei Wu, Chengfang Wang, Yanyan Dong, Liping Wang, Chunchun He, Yan Yang, Chunpeng Zou, Xiangjun Liu, Dihua Shangguan, Ming Gao, Linlin Sun, Thomas J. Webster, Zhe Liu
Chapter 4. Translational Clinical Applications of Micro-/Nanoimaging Probes: Challenges and Perspectives
Abstract
With the upgraded innovations in material science and translational medicine, micro-/nanoimaging probes show great promises for clinical translations to serve human healthcare. A number of micro-/nanoimaging probes have been approved for clinical imaging in US, CT, PET, SPECT, etc., and tremendous agents are at the status of clinical trials or under translations. This chapter focuses on the current commercially available imaging probes and their biomedical roles in disease diagnosis for patients. The potential challenges and future perspectives of imaging probes under evaluation are also briefly disclosed.
Senmin Wu, Hui Zhu, Jianle Huang, Kai Chen, Yan Yang, Chunpeng Zou, Zhe Liu
Chapter 5. Outlook for Next-Generation Micro-/Nanoimaging Probes
Abstract
Innovations for the next-generation of micro-/nanoimaging probes require multiple functions and roles to serve not only targeted imaging but also precision treatments. That is, the development of theranostic agents used for visualized medicine, image-guided therapy, or image-navigated surgery will dramatically extend their application scope, boost processing for clinical uses and bridge materials, and integrate bioengineering and medicine. This chapter provides an outlook for this bright future and focuses on several ever-growing subjects, including aggregation-induced emission probes, image-guided treatment technologies, and nanoimaging probes for bacteria detection.
Run Chang, Ming Gao, Linlin Sun, Doudou Wang, Zhe Liu, Thomas J. Webster
Metadaten
Titel
Advances in Functional Micro-/Nanoimaging Probes
herausgegeben von
Zhe Liu
Copyright-Jahr
2018
Verlag
Springer Singapore
Electronic ISBN
978-981-10-4804-3
Print ISBN
978-981-10-4803-6
DOI
https://doi.org/10.1007/978-981-10-4804-3

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