nach oben

Erschienen in:

2019 | OriginalPaper | Buchkapitel

13. Antidiabetic and Antioxidant Activities of Bioactive Compounds from Endophytes

verfasst von : Rosa Martha Perez Gutierrez, Adriana Neira González

Erschienen in: Endophytes and Secondary Metabolites

Verlag: Springer International Publishing

Einloggen

Aktivieren Sie unsere intelligente Suche, um passende Fachinhalte oder Patente zu finden.

search-config

KI-gestützte Suche

Aus

Abstract

The aim of the present chapter is to appraise the phytochemical and pharmacological potential of the endophytes. This chapter will further highlight the future research prospects of the study of endophytes with antioxidant and antidiabetic activities. Informations on endophytes were obtained from related publications using electronic scientific databases. Based on previous reports, it could be said that the endophytes have emerged as excellent source of compounds which could be used for the treatment of skin diseases and microbial infections and as anticancer and anti-inflammatory agents. The studies provide new knowledge on the isolation and characterization of novel bioactives especially in the discovery of novel therapeutic drugs with antioxidant and antidiabetic properties. however, current research on the pharmacological properties of all the endophyte species including bioassay-guided isolation of phytoconstituents and their mechanism of action, pharmacokinetics, bioavailability, efficacy, and safety should be carried out in the future to add more value to this study.

Sie haben noch keine Lizenz? Dann Informieren Sie sich jetzt über unsere Produkte:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

über 102.000 Bücher
über 537 Zeitschriften

aus folgenden Fachgebieten:

Automobil + Motoren
Bauwesen + Immobilien
Business IT + Informatik
Elektrotechnik + Elektronik
Energie + Nachhaltigkeit
Finance + Banking
Management + Führung
Marketing + Vertrieb
Maschinenbau + Werkstoffe
Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

Jetzt informieren

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

über 67.000 Bücher
über 390 Zeitschriften

aus folgenden Fachgebieten:

Automobil + Motoren
Bauwesen + Immobilien
Business IT + Informatik
Elektrotechnik + Elektronik
Energie + Nachhaltigkeit
Maschinenbau + Werkstoffe

Jetzt Wissensvorsprung sichern!

Jetzt informieren

Vorheriges Kapitel Diversity of Plant Endophytic Volatile Organic Compound (VOC) and Their Potential Applications

Nächstes Kapitel Fungal Endophytes: A Novel Source of Cytotoxic Compounds

Sell DR, Monnier VM (2012) Molecular basis of arterial stiffening: role of glycation – a mini-review. Gerontology 58(3):227–237. https://doi.org/10.1159/000334668CrossRefPubMed

Guariguata L, Whiting DR, Hambleton I, Beagley J, Linnenkamp U, Shaw JE (2014) Global estimates of diabetes prevalence for 2013 and projections for 2035. Diabetes Res Clin Pract 103:137–149. https://doi.org/10.1016/j.diabres.2013.11.002CrossRefPubMed

Klonoff DC, Schwartz DM (2000) An economic analysis of interventions for diabetes. Diabetes Care 23:390–404CrossRefPubMed

Fatmah A, Siti B, Zariyantey A, Nasar A, Jamaludin M (2012) The role of oxidative stress and antioxidants in diabetic complications. Sultan Qaboos Univ Med J 12:5–18CrossRef

Perez RM, Flores LB, Neira AM (2012) Evaluation of the antioxidant and anti-glication effects of the hexane extract from piper auritum leaves in Vitro and beneficial activity on oxidative stress and advanced glycation end-product-mediated renal injury in streptozotocin-treated diabetic rats. Molecules 17, 11897–11919. https://doi.org/10.3390/molecules171011897CrossRef

Giugliano D, Ceriello A, Paolisso G (1996) Oxidative stress and diabetic vascular complications. Diabetes Care 19(3):257–267CrossRefPubMed

Yavuz O, Cam M, Bukan N, Guven A, Silan F (2003) Protective effect of melatonin on beta-cell damage in streptozotocin induced diabetes in rats. Acta Histochem 105:261–266CrossRefPubMed

Valko M, Rhodes CJ, Moncol J, Izakovic M, Mazur M (2006) Free radicals, metals and antioxidants in oxidative stress induced cancer. Chem Biol Interact 160:1–40. https://doi.org/10.1016/j.cbi.2005.12.009CrossRefPubMed

Saxena AK, Srivastava P, Kale RK, Baquer NZ (1993) Impaired antioxidant status in diabetic rat liver. Effect of vanadate. Biochem Pharmacol 45(3):539–542CrossRefPubMed

10.

Maritim AC, Sanders RA, Watkins JB 3rd (2003) Diabetes, oxidative stress, and antioxidants: a review. J Biochem Mol Toxicol 17:24–38. https://doi.org/10.1002/jbt.10058.CrossRefPubMed

11.

Pocernich CB, Cardin AL, Racine CL, Lauderback CM, Butterfield DA (2001) Glutathione elevation and its protective role in acrolein-induced protein damage in synaptosomal membranes: relevance to brain lipid peroxidation in neurodegenerative disease. Neurochem Int 39:141–149CrossRefPubMed

12.

Kaysen GA, Dubin JA, Müller HG, Mitch WE, Rosales LM, Levin NW (2002) Relationships among inflammation nutrition and physiologic mechanisms establishing albumin levels in hemodialysis patients. Kidney Int 61:2240–2249. https://doi.org/10.1046/j.1523-1755.2002.00076.xCrossRefPubMed

13.

Andrade-Cetto A, Heinrich M (2005) Mexican plants with hypoglycaemic effect used in the treatment of diabetes. J Ethnopharmacol 99:325–348. https://doi.org/10.1016/j.jep.2005.04.019CrossRefPubMed

14.

Grover JK, Yadav S, Vats V (2002) Medicinal plants of India with anti-diabetic potential. J Ethnopharmacol 81:81–100. https://doi.org/10.1016/j.jep.2005.04.019CrossRefPubMed

15.

Vinayagam R, Xu B (2015) Antidiabetic properties of dietary flavonoids: a cellular mechanism review. Nutr Metab (Lond) 12:60–64. https://doi.org/10.1186/s12986-015-0057-7CrossRef

16.

Nagalingam A, Arbiser JL, Bonner MY, Saxena NK, Sharma D (2012) Honokiol activates AMP-activated protein kinase in breast cancer cells via an LKB1-dependent pathway and inhibits breast carcinogénesis. Breast Cancer Res 14(1):R35. https://doi.org/10.1186/bcr3128CrossRefPubMedPubMedCentral

17.

Coughlan KA, Valentine RJ, Ruderman NB, Saha AK (2014) AMPK activation: a therapeutic target for type 2 diabetes? Diabetes Metab Syndr Obes 7:241–253. https://doi.org/10.2147/DMSO.S43731CrossRefPubMedPubMedCentral

18.

Musi N, Hirshman MF, Nygren J, Svanfeldt M, Bavenholm P, Rooyackers O, Zhou G, Williamson GM, Ljunqvist O, Efendic S, Moller DE, Thorell A, Goodyear LJ (2002) Metformin increases AMP-activated protein kinase activity in skeletal muscle of subjects with type 2 diabetes. Diabetes 51:2074–2081CrossRefPubMed

19.

Zhou G, Myers R, Li Y, Chen Y, Shen X, Fenyk-Melody J, Wu M, Ventre J, Doebber T, Fujii N, Musi N, Hirshman MF, Goodyear LJ, Moller DE (2001) Role of AMP-activated protein kinase in mechanism of metformin action. J Clin Invest 108:1167–1174. https://doi.org/10.1172/JCI13505CrossRefPubMedPubMedCentral

20.

Debbab A, Aly AH, Edrada-Ebel R, Wray V, Müller WE, Totzke F, Zirrgiebel U, Schächtele C, Kubbutat MH, Lin WH, Mosaddak M, Hakiki A, Proksch P, Ebel R (2009) Bioactive metabolites from the endophytic fungus Stemphylium globuliferum isolated from Mentha pulegium. J Nat Prod 72(4):626–631. https://doi.org/10.1021/np8004997CrossRefPubMed

21.

Wibowo M, Prachyawarakorn V, Aree T, Wiyakrutta S, Mahidol C, Ruchirawat S, Kittakoop P (2014) Tricyclic and spirobicyclic norsesquiterpenes from the endophytic fungus Pseudolagarobasidium acaciicola. Eur J Org Chem 19:3976–3980. https://doi.org/10.1016/j.phytochem.2015.11.016CrossRef

22.

Ludwig-Müller J (2015) Plants and endophytes: equal partners in secondary metabolite production? Biotechnol Lett 37:1325–1334. https://doi.org/10.1007/s10529-015-1814-4CrossRefPubMed

23.

Bérdy J (2012) Thoughts and facts about antibiotics: where we are now and where we are heading. J Antibiot 65:385–395. https://doi.org/10.1038/ja.2012.27CrossRef

24.

Banerjee D (2011) Endophytic fungal diversity in tropical and subtropical plants. Res J Microbiol 6:54–62. https://doi.org/10.3923/jm.2011.54.62CrossRef

25.

González V, Tello ML (2011) The endophytic mycota associated with Vitis vinifera in Central Spain. Fungal Divers 47:29–42. https://doi.org/10.1128/AEM.07655-11CrossRef

26.

Araújo WL, Saridakis HO, Barroso PAV, Aguilar-Vildoso CI, Azevedo JL (2001) Variability and interactions between endophytic bacteria and fungi isolated from leaf tissues of citrus rootstocks. Can J Microbiol 47:229–236CrossRefPubMed

27.

Strobel GA (2002) Rainforest endophytes and bioactive products. Crit Rev Biotechnol 22:315–333. https://doi.org/10.1080/07388550290789531CrossRefPubMed

28.

Strobel G, Daisy B, Castillo U, Harper J (2004) Natural products from endophytic microorganisms. J Nat Prod 67:257–268. https://doi.org/10.1021/np030397vCrossRefPubMed

29.

Katoch M, Salgotra A, Singh G (2014) Endophytic fungi found in association with Bacopa monnieri as resourceful producers of industrial enzymes and antimicrobial bioactive natural products. Braz Arch Biol Technol 57:714–722. https://doi.org/10.1590/S1516-8913201402502CrossRef

30.

Katoch M, Singh G, Sharma S, Gupta N, Sangwan PL, Saxena AK (2014) Cytotoxic and antimicrobial activities of endophytic fungi isolated from Bacopa monnieri (L.) Pennell (Scrophulariaceae). BMC Complement Altern Med 14:52–58. https://doi.org/10.1186/1472-68821452CrossRefPubMedPubMedCentral

31.

Qadri M, Johri S, Shah BA, Khajuria A, Sidiq T, Lattoo SK, Abdin MZ, Riyaz-ulHasan S (2013) Identification and bioactive potential of endophytic fungi isolated from selected plants of the western Himalayas. Springerplus 2:8. https://doi.org/10.1186/2193-1801-2-8CrossRefPubMedPubMedCentral

32.

Bhatnagar I, Kim SK (2010) Marine antitumor drugs: status, shortfalls and strategies. Mar Drugs 8:2702–2720. https://doi.org/10.3390/md8102702CrossRefPubMedPubMedCentral

33.

Kohlmeyer J, Kohlmeyer E (1979) Marine mycology. Elsvier, London, UK, p 704

34.

Blackwell M (2011) The Fungi: 1, 2, 3 ... 5.1 million species? Am J Bot 98:426–438. https://doi.org/10.3732/ajb.1000298CrossRefPubMed

35.

Wilson D, Barr ME, Faeth SH (1997) Ecology and description of a new species of Ophiognomonia endophytic in the leaves of Quercus emoryi. Mycologia 89:537–546. https://doi.org/10.2307/3760988CrossRef

36.

Xie G, Zhu X, Li Q, Gu M, He Z, Wu J, Li J, Lin Y, Li M, She Z (2010) SZ-685C, a marine anthraquinone, is a potent inducer of apoptosis with anticancer activity by suppression of the Akt/FOXO pathway. Br J Pharmacol 159:689–697. https://doi.org/10.1111/j.1476-5381.2009.00577.xCrossRefPubMedPubMedCentral

37.

Ramos S (2008) Effect of dietary flavonoids on apoptotic pathways related to cancer chemoprevention. J Nutr Biochem 18:427–442. https://doi.org/10.1016/j.jnutbio.2006.11.004CrossRef

38.

World Health Organization (2014) Global status on noncommunicable diseases 2014. WHO Press, Geneva

39.

Shahidi SF, Ambigaipalan P (2015) Phenolics and polyphenolics in food beverages and spices: antioxidants activity and health effects-review. J Funct Food 18:820–897CrossRef

40.

Xanthis A, Hatzitolios A, Koliakos G, Tatola V (2007) Advanced glycosylation end products and nutrition-A possible relation with diabetic aterosclerosis and how to prevent it. J Food Sci 72:R125–R129. https://doi.org/10.1111/j.1750-3841.2007.00508.xCrossRefPubMed

41.

Devi KA, Pandey G, Rawat AKS, Sharma GD, Pandey P (2017) The endophytic symbiont – Pseudomonas aeruginosa stimulates the antioxidant activity and growth of Achyranthes aspera L. Front Microbiol 8:1897–1905. https://doi.org/10.3389/fmicb.2017.01897CrossRefPubMedPubMedCentral

42.

Mani VM, Parimala AJ, Soundari G, Karthiyaini D, Preethi K (2015) Bioprospecting endophytic fungi and their metabolites from medicinal tree Aegle marmelos in Western Ghats. India Mycobiol 43(3):303–310. https://doi.org/10.5941/MYCO.2015.43.3.303. Published online 2015 Sep 30CrossRef

43.

Khan AL, Gilani SA, Waqas M, Al-hosni K, Al-khiziri S, Kim Y, Ali L, Kang S, Asaf S, Shahzad R, Hussain J, Lee I, Al-harrasi A (2017) Endophytes from medicinal plants and their potential for producing indole acetic acid, improving seed germination and mitigating oxidative stress. J Zhejiang Univ-Sci B (Biomed Biotechnol) 18:125–137. https://doi.org/10.1631/jzus.B1500271CrossRef

44.

Netala VR, Kotakadi VS, Bobbu P, Gaddam SA, Tartte V (2016) Endophytic fungal isolate mediated biosynthesis of silver nanoparticles and their free radical scavenging activity and anti microbial studies. 3 Biotech 6:132. https://doi.org/10.1007/s13205-016-0433-7CrossRefPubMedPubMedCentral

45.

Ascêncio PGM, Ascêncio SD, Aguiar AA, Fiorini A, Pimenta RZ (2014) Chemical assessment and antimicrobial and antioxidant activities of endophytic fungi extracts isolated from Costus spiralis (Jacq.) Roscoe (Costaceae). Evid Based Complement Alternat Med 2014:190543. https://doi.org/10.1155/2014/190543. 10 pagesCrossRefPubMedPubMedCentral

46.

Nath A, Raghunatha P, Joshi SR (2012) Diversity and biological activities of endophytic fungi of Emblica officinalis, an ethnomedicinal plant of India. Mycobiology 40(1):8–13. https://doi.org/10.5941/MYCO.2012.40.1.008CrossRefPubMedPubMedCentral

47.

Yadav M, Yadav A, Kumar S, Yadav JP (2016) Spatial and seasonal influences on culturable endophytic mycobiota associated with different tissues of Eugenia jambolana Lam. and their antibacterial activity against MDR strains. BMC Microbiol 16:44. https://doi.org/10.1186/s12866-016-0664-0CrossRefPubMedPubMedCentral

48.

Pan F, Su T, Cai S, Wu W (2017) Fungal endophyte-derived Fritillaria unibracteata var. wabuensis: diversity, antioxidant capacities in vitro and relations to phenolic, flavonoid or saponin compounds. Sci Rep. https://doi.org/10.1038/srep42008

49.

Srinivasan K, Jagadish LK, Shenbhagaraman R, Muthumary J (2010) Antioxidant activity of endophytic fungus Phyllosticta sp. isolated from Guazuma tomentosa. J Phytology 2:37–41

50.

Netala VR, Bethu MS, Pushpalatha B, Baki VB, Aishwarya S, Rao JR, Tartte V (2016) Biogenesis of silver nanoparticles using endophytic fungus Pestalotiopsis microspora and evaluation of their antioxidant and anticancer activities. Int J Nanomedicine 11:5683–5696. https://doi.org/10.2147/IJN.S112857CrossRefPubMedPubMedCentral

51.

Ding G, Li Y, Fu S, Liu S, Wei J, Che Y (2009) Ambuic acid and torreyanic acid derivatives from the endolichenic fungus Pestalotiopsis sp. J Nat Prod 72:182–186. https://doi.org/10.1021/np800733yCrossRefPubMed

52.

Lee JC, Lobkovsky E, Pliam NB, Strobel G, Clardy J (1995) Subglutinols A and B: immunosuppressive compounds from the endophytic fungus Fusarium subglutinans. J Org Chem 60:7076–7077. https://doi.org/10.1021/jo00127a001CrossRef

53.

Elfita M, Munawar R (2012) Isolation of antioxidant compound from endophytic fungi Acremonium sp. from the Twigs of Kandis Gajah. Makara J Sci 16:46–50. https://doi.org/10.7454/mss.v16i1.1280CrossRef

54.

Seetharaman P, Gnanasekar S, Chandrasekaran R, Chandrakasan G, Kadarkarai M, Sivaperumal S (2017) Isolation and characterization of anticancer flavone chrysin (5,7-dihydroxy flavone)-producing endophytic fungi from Passiflora incarnata L. leaves. Ann Microbiol 67:321–331. https://doi.org/10.1007/s13213-017-1263-5CrossRef

55.

Wang L, Qiu P, Long XF, Zhang S, Zeng ZG, Tian YQ (2016) Comparative analysis of chemical constituents, antimicrobial and antioxidant activities of ethylacetate extracts of Polygonum cuspidatum and its endophytic actinomycete, Streptomyces sp. A0916. Chin J Nat Med 14:117–123. https://doi.org/10.1016/S1875-5364(16)60004-3CrossRefPubMed

56.

Cui J-L, Guo T-T, Ren Z-X, Zhang N-S, Wang M-L (2015) Diversity and antioxidant activity of culturable endophytic fungi from Alpine plants of Rhodiola crenulata, R. angusta, and R. sachalinensis. PLoS One 10:e0118204. https://doi.org/10.1371/journal.pone.0118204CrossRefPubMedPubMedCentral

57.

Surveswaran S, Cai YZ, Corke H, Sun M (2007) Systematic evaluation of natural phenolic antioxidants from 133 Indian medicinal plants. Food Chem 102:938–953. https://doi.org/10.1016/j.foodchem.2006.06.033CrossRef

58.

Panossiana A, Hammb R, Wikmana G, Efferth T (2014) Mechanism of action of Rhodiola, salidroside, tyrosol and triandrin in isolated neuroglial cells: an interactive pathway analysis of the downstream effects using RNA microarray data. Phytomedicine 21:1325–1348. https://doi.org/10.1016/j.phymed.2014.07.008CrossRef

59.

Sadananda TS, Nirupama R, Chaithra K, Govindappa M, Chandrappa CP, Vinay Raghavendra B (2011) Antimicrobial and antioxidant activities of endophytes from Tabebuia argentea and identification of anticancer agent (lapachol). J Med Plants Res 5:3643–3652

60.

Li Y, Xin X, Chang Z, Shi R, Miao Z, Ding J, Hao G (2015) The endophytes fungi from Salvia miltiorrhiza Bge.f. alba are a potential source of natural antioxidants. Bot Stud 565:1–7. https://doi.org/10.1186/S40529-015-0086-6CrossRef

61.

Zeng PY, Wu JG, Liao LM, Chen TQ, Wu JZ, Wong K-H (2011) In vitro antioxidant activities of endophytic fungi isolated from the liverwort Scapania verrucosa. Genet Mol Res 10:3169–3179. https://doi.org/10.4238/2011.December.20.1CrossRefPubMed

62.

Huang WY, Cai YZ, Hyde KD, Corke H, Sun M (2008) Biodiversity of endophytic fungi associated with 29 traditional Chinese medicinal plants. Fungal Divers 33:61–75

63.

Khiralla A, Mohamed I, Thomas J, Mignard B, Spina R, Yagi S, Laurain-Mattar D (2015) A pilot study of antioxidant potential of endophytic fungi from some Sudanese medicinal plants. Asian Pac J Trop Med 8:701–704. https://doi.org/10.3923/ajps.2016.8.15CrossRefPubMed

64.

Strobel G, Ford E, Worapong J, Harper JK, Arif AM, Grant DM, Fung PCW, Chaud RMW (2002) Isopestacin, an isobenzofuranone from Pestalotiopsis microspora, possessing antifungal and antioxidant activities. Phytochemistry 60:179–183CrossRefPubMed

65.

Song YC, Huang WY, Sun C, Wang EW, Tan RX (2005) Characterization of graphislactone A as the antioxidant and free radical-scavenging substance from the culture of Cephalosparium sp1FB-E001, an endophytic fungus in Trachelospermum jasminoides. Biol Pharm Bull 28:506–509CrossRefPubMed

66.

Artanti N, Tachibana S, Kardono LB, Sukiman H (2012) Isolation of alpha-glucosidase inhibitors produced by an endophytic fungus, Colletotrichum sp. TSC13 from Taxus sumatrana. Pak J Biol Sci 15(14):673–679. https://doi.org/10.3923/pjbs.2012.673.679CrossRefPubMed

67.

Artanti N, Tachibana S, Kardono LB (2014) Effect of media compositions on α-glucosidase inhibitory activity, growth and fatty acid content in mycelium extracts of Colletotrichum sp. TSC13 from Taxus Sumatrana (Miq.) de Laub. Pak J Biol Sci 17:884–890. https://doi.org/10.3923/pjbs.2014.884.890CrossRefPubMed

68.

Artanti N, Tachibana S, Kardono LB, Sukiman H (2011) Screening of endophytic fungi having ability for antioxidative and alpha-glucosidase inhibitor activities isolated from Taxus sumatrana. Pak J Biol Sci 14(22):1019–1023. https://doi.org/10.3923/pjbs.2011.1019.1023CrossRefPubMed

69.

Singh B, Sharma P, Kumar A, Chadha P, Kaur R, Kaur A (2016) Antioxidant and in vivo genoprotective effects of phenolic compounds identified from an endophytic Cladosporium velox and their relationship with its host plant Tinospora cordifolia. J Ethnopharmacol 194:450–456. https://doi.org/10.1016/j.jep.2016.10.018CrossRefPubMed

70.

Zhou J, Diao X, Wang T, Chen G, Lin Q, Yang X, Xu J (2018) Phylogenetic diversity and antioxidant activities of culturable fungal endophytes associated with the mangrove species Rhizophora stylosa and R. mucronata in the South China Sea. PLoS One 13(6):e0197359. https://doi.org/10.1371/journal.pone.0197359CrossRefPubMedPubMedCentral

71.

Zhang W (2014) Phomopsidone A, a novel depsidone metabolite from the mangrove endophytic fungus Phomopsis sp. A123. Fitoterapia 96:146. https://doi.org/10.1016/j.fitote.2014.05.001CrossRefPubMed

72.

Wang J, Cox DG, Ding W, Huang G, Lin Y, Li C (2014) Three new resveratrol derivatives from the mangrove endophytic fungus Alternaria sp. Mar Drugs 12:2840–2850. https://doi.org/10.3390/md12052840CrossRefPubMedPubMedCentral

73.

Choe E, Min DB (2009) Mechanisms of antioxidants in the oxidation of foods. Compr Rev Food Sci Food Saf 8:345–358. https://doi.org/10.1111/j.1541-4337.2009.00085.xCrossRef

74.

Rice-Evans CA, Miller NJ, Paganga G (1996) Structure-antioxidant activity relationships of flavonoids and phenolic acids. Free Radic Biol Med 20:933–956CrossRefPubMed

75.

Rodríguez J, Olea-Azar C, Cavieres C, Norambuena E, Delgado-Castro T, Soto-Delgado J, Araya-Maturana R (2007) Antioxidant properties and free radical-scavenging reactivity of a family of hydroxynaphthalenones and dihydroxyanthracenones. Bioorg Med Chem 15:7058–7065. https://doi.org/10.1016/j.bmc.2007.07.013CrossRefPubMed

76.

Dong-Li L, Li X, Wang B (2009) Natural anthraquinone derivatives from a marine mangrove plant derived endophytic fungus Eurotium rubrum: structural elucidation and DPPH radical scavenging activity. J Microbiol Biotechnol 19:675–680. https://doi.org/10.4014/jmb.0805.342CrossRef

77.

Singh B, Kaur A (2015) Antidiabetic potential of a peptide isolated from an endophytic Aspergillus awamori. J Appl Microbiol 120:301–311. https://doi.org/10.1111/jam.12998CrossRef

78.

Ushasri R, Anusha R (2015) In vitro anti-diabetic activity of ethanolic and acetone extracts of endophytic fungi Syncephalastrum racemosum isolated from the seaweed Gracilaria corticata by alpha-amylase inhibition assay method. Int J Curr Microbiol Appl Sci 4:254–259

79.

Mishra PD, Verekar SA, Kulkarni-Almeida A, Roy SK, Jain S, Balakrishnan A, Vishwakarma R, Deshmuk SK (2013) Anti-inflammatory and anti-diabetic naphthaquinones from an endophytic fungus Dendryphion nanum (Nees) S. Hughes Indian J Chem 52B:565–556

80.

Huang R, Jiang BG, Li XN, Wang YT, Liu SS, Zheng KX, He J, Wu SH (2018) Polyoxygenated cyclohexenoids with promising α-glycosidase inhibitory activity produced by Phomopsis sp. YE3250, an endophytic fungus derived from Paeonia delavayi. J Agric Food Chem 66:1140–1146. https://doi.org/10.1021/acs.jafc.7b04998CrossRefPubMed

81.

Gutiérrez-García K, Neira-González A, Pérez-Gutiérrez RM, Granados-Ramírez G, Zarraga R, Wrobel K, Barona-Gómez F, Flores-Cotera LB (2017) Phylogenomics and inhibitory activity upon the formation of advanced glycation end-products of 2, 4-diacetylphloroglucinol-producing Pseudomonas endophytes from Piper auritum. J Nat Prod 80:1955–1963. https://doi.org/10.1021/acs/natprod.6b00823CrossRefPubMed

82.

Dhankhar S, Yadav JP (2013) Investigations towards new antidiabetic drugs from fungal endophytes associated with Salvadora oleoides Decne. Med Chem 9:624–632CrossRefPubMed

83.

Kumar KM, Chandrappa CP, Channabasava R, Ramachandra YL, Padmalatha RS, Ravishankar RV, Govindappa M (2017) Anti-diabetic activity of endophytic fungi, Penicillium species of Tabebuia argentea; in silico and experimental analysis. Res J Phytochem 11:90–110CrossRef

84.

Govindappa M, Channabasava R, Sunil Kumar KR, Pushpalatha KC (2013) Antioxidant activity and phytochemical screening of crude endophytes extracts of Tabebuia argentea Bur. & K. Sch. Am J Plant Sci 4:1641–1652. https://doi.org/10.4236/ajps.2013.48198CrossRef

85.

Katoch M, Paul A, Singh G, Sridhar SNC (2017) Fungal endophytes associated with Viola odorata Linn. as bioresource for pancreatic lipase inhibitors. BMC Complement Altern Med 17:385. https://doi.org/10.1186/s12906-017-1893-yCrossRefPubMedPubMedCentral

86.

Govindappa M, Sadananda TS, Channabasava, Ramachandra YL, Chandrappa CP, Padmalatha RS, Prasad SK (2015) In vitro and in vivo antidiabetic activity of lectin (N-acetylgalactosamine, 64 kDa) isolated from endophytic fungi, Alternaria species from Viscum album on alloxan induced diabetic rats. Integr Obesity Diabetes 1:11–19

87.

Song Y, Wang J, Huang H, Ma L, Wang J, Gu Y, Liu L, Lin Y (2012) Four eremophilane sesquiterpenes from the mangrove endophytic fungus Xylaria sp. BL321. Mar Drugs 10:340–348. https://doi.org/10.3390/md10020340CrossRefPubMedPubMedCentral

88.

Zhang L, Niaz SI, Khan D, Wang Z, Zhu Y, Zhou H, Lin Y, Li J, Liu L (2017) Induction of diverse bioactive secondary metabolites from the mangrove endophytic fungus Trichoderma sp. (Strain 307) by co-cultivation with Acinetobacter johnsonii (Strain B2). Mar Drugs 15:35. https://doi.org/10.3390/md1502003CrossRefPubMedCentral

89.

Cui H, Liu Y, Nie Y, Liu Z, Chen S, Zhang Z, Lu Y, He L, Huang X, She Z (2016) polyketides from the mangrove-derived endophytic fungus Nectria sp. HN001 and their α-glucosidase inhibitory activity. Mar Drugs 14:86–95. https://doi.org/10.3390/md1405008CrossRefPubMedCentral

Titel: Antidiabetic and Antioxidant Activities of Bioactive Compounds from Endophytes
verfasst von: Rosa Martha Perez Gutierrez
Adriana Neira González
Verlag: Springer International Publishing
Buch: Endophytes and Secondary Metabolites
Print ISBN: 978-3-319-90483-2

Electronic ISBN: 978-3-319-90484-9

Copyright-Jahr: 2019
DOI: https://doi.org/10.1007/978-3-319-90484-9_30

Premium Partner

Marktübersichten

Die im Laufe eines Jahres in der „adhäsion“ veröffentlichten Marktübersichten helfen Anwendern verschiedenster Branchen, sich einen gezielten Überblick über Lieferantenangebote zu verschaffen.

Zur Marktübersicht