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2021 | OriginalPaper | Buchkapitel

5. Aptamer Mediated Sensing of Environmental Pollutants Utilizing Peroxidase Mimic Activity of NanoZymes

verfasst von : Neeti Kalyani, Bandhan Chatterjee, Tarun Kumar Sharma

Erschienen in: Nanozymes for Environmental Engineering

Verlag: Springer International Publishing

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Abstract

Environmental pollution is a global health concern, affecting millions of lives. With the current pace of industrialization and unabated anthropogenic activities, the global burden of environmental pollutants is bound to rise. These pollutants take a heavy toll on human health, are also a major cause of global death and reduced life expectancy. They rapidly invade biospheres, including air, soil, and aquatic environment. From here, they find their way into the various food chain/webs and results in bioaccumulation and biomagnification, in a way affecting every member of the chain. Thus, there is an urgent need to combat this menace, and for any effective management first, there has to be an estimation of the extent and amount of contamination.
Here comes the role of various pollutant sensors, a part traditionally confined to sophisticated and expensive instrumentation and methods. However, the combination of NanoZymes (nanoparticles exhibiting enzymatic properties) and aptamers (chemical substitutes of antibody) have revolutionized the field of sensing altogether. The NanoZymes, on the one hand, are inexpensive, and robust signal generating moiety works fluidly with aptamers. The aptamers, which can be economically produced with batch consistency, have excellent recognition ability. The combination of the duo has been reported to work efficiently in the existing biosensing platforms like lateral flows and electrochemical sensors.
This chapter first concisely introduces the reader to the basic principle of the aptamer-nanozyme sensing mechanism and provides insights into the recent advancements in the field of aptamer nanozyme-based pollutant sensing. Major advances include the development of new combinations of nanomaterials, new shapes of nanomaterials to enhance the sensitivity of the biosensor. The last decade has also witnessed the development of high affine and specific aptamers for a host of environmental pollutants, which aptly supplements the development of sensors by providing novel and high-performance recognition elements for them. Additionally, due emphasis has been laid to develop mobile Point-of-Care (POC)/on-site sensors that do not need sophisticated instrumentation, trained manpower, and also comes at an affordable cost. These sensors will enable rapid, affordable on-site detection of environmental pollutants.

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Literatur
Zurück zum Zitat Bazin I, Tria SA, Hayat A, Marty JL (2017) New biorecognition molecules in biosensors for the detection of toxins. Biosens Bioelectron 87:285–298CrossRef Bazin I, Tria SA, Hayat A, Marty JL (2017) New biorecognition molecules in biosensors for the detection of toxins. Biosens Bioelectron 87:285–298CrossRef
Zurück zum Zitat Chatterjee B, Kalyani N, Das S et al (2019) Nano-realm for point-of-care (POC) bacterial diagnostics. In: Methods in microbiology, 1st edn. Elsevier, New York, pp 19–42 Chatterjee B, Kalyani N, Das S et al (2019) Nano-realm for point-of-care (POC) bacterial diagnostics. In: Methods in microbiology, 1st edn. Elsevier, New York, pp 19–42
Zurück zum Zitat Das R, Dhiman A, Kapil A et al (2019) Aptamer-mediated colorimetric and electrochemical detection of Pseudomonas aeruginosa utilizing peroxidase-mimic activity of gold NanoZyme. Anal Bioanal Chem 411:1229–1238CrossRef Das R, Dhiman A, Kapil A et al (2019) Aptamer-mediated colorimetric and electrochemical detection of Pseudomonas aeruginosa utilizing peroxidase-mimic activity of gold NanoZyme. Anal Bioanal Chem 411:1229–1238CrossRef
Zurück zum Zitat Dhiman A, Kalra P, Bansal V et al (2017) Aptamer-based point-of-care diagnostic platforms. Sensors Actuators B Chem 246:535–553CrossRef Dhiman A, Kalra P, Bansal V et al (2017) Aptamer-based point-of-care diagnostic platforms. Sensors Actuators B Chem 246:535–553CrossRef
Zurück zum Zitat Gahlaut SK, Kalyani N, Sharan C et al (2019) Smartphone based dual mode in situ detection of viability of bacteria using Ag nanorods array. Biosens Bioelectron 126:478–484CrossRef Gahlaut SK, Kalyani N, Sharan C et al (2019) Smartphone based dual mode in situ detection of viability of bacteria using Ag nanorods array. Biosens Bioelectron 126:478–484CrossRef
Zurück zum Zitat Jayasena SD (1999) Aptamers: an emerging class of molecules that rival antibodies in diagnostics. Clim Chem 45:1628–1650CrossRef Jayasena SD (1999) Aptamers: an emerging class of molecules that rival antibodies in diagnostics. Clim Chem 45:1628–1650CrossRef
Zurück zum Zitat Kalyani N, Goel S, Jaiswal S (2020) Point-of-care sensors for on-site detection of pesticides. In: Kumar Tuteja S, Arora D, Dilbaghi N, Lichtfouse E (eds) Nanosensors for environmental applications. Springer, Cham, pp 197–224CrossRef Kalyani N, Goel S, Jaiswal S (2020) Point-of-care sensors for on-site detection of pesticides. In: Kumar Tuteja S, Arora D, Dilbaghi N, Lichtfouse E (eds) Nanosensors for environmental applications. Springer, Cham, pp 197–224CrossRef
Zurück zum Zitat Kaur H, Chaterjee B, Bruno JG, Sharma TK (2019) Defining target product profiles (TPPs) for aptamer-based diagnostics. In: Advances in biochemical engineering/biotechnology. Springer, Berlin/Heidelberg, pp 1–12 Kaur H, Chaterjee B, Bruno JG, Sharma TK (2019) Defining target product profiles (TPPs) for aptamer-based diagnostics. In: Advances in biochemical engineering/biotechnology. Springer, Berlin/Heidelberg, pp 1–12
Zurück zum Zitat Kumar S, Lodhi DK, Goel P et al (2015) A facile method for fabrication of buckled PDMS silver nanorod arrays as active 3D SERS cages for bacterial sensing. Chem Commun 51:12411–12414CrossRef Kumar S, Lodhi DK, Goel P et al (2015) A facile method for fabrication of buckled PDMS silver nanorod arrays as active 3D SERS cages for bacterial sensing. Chem Commun 51:12411–12414CrossRef
Zurück zum Zitat Rockström J, Steffen W, Noone K et al (2009) A safe operation space for humanity. Nature 461:472–475CrossRef Rockström J, Steffen W, Noone K et al (2009) A safe operation space for humanity. Nature 461:472–475CrossRef
Zurück zum Zitat Sharma TK, Bruno JG, Cho WC (2016) The point behind translation of aptamers for point of care diagnostics. Aptamers Synth Antibodies 2:36–42 Sharma TK, Bruno JG, Cho WC (2016) The point behind translation of aptamers for point of care diagnostics. Aptamers Synth Antibodies 2:36–42
Zurück zum Zitat Sharma TK, Bruno JG, Dhiman A (2017) ABCs of DNA aptamer and related assay development. Biotechnol Adv 35:275–301CrossRef Sharma TK, Bruno JG, Dhiman A (2017) ABCs of DNA aptamer and related assay development. Biotechnol Adv 35:275–301CrossRef
Zurück zum Zitat Taghdisi SM, Danesh NM, Ramezani M et al (2018) Novel colorimetric aptasensor for zearalenone detection based on nontarget-induced aptamer walker, gold nanoparticles, and exonuclease-assisted recycling amplification. ACS Appl Mater Interfaces 10:12504–12509. https://doi.org/10.1021/acsami.8b02349CrossRef Taghdisi SM, Danesh NM, Ramezani M et al (2018) Novel colorimetric aptasensor for zearalenone detection based on nontarget-induced aptamer walker, gold nanoparticles, and exonuclease-assisted recycling amplification. ACS Appl Mater Interfaces 10:12504–12509. https://​doi.​org/​10.​1021/​acsami.​8b02349CrossRef
Zurück zum Zitat Tchounwou PB, Yedjou CG, Patlolla AK, Sutton DJ (2012) Heavy metals toxicity and the environment. Springer, BaselCrossRef Tchounwou PB, Yedjou CG, Patlolla AK, Sutton DJ (2012) Heavy metals toxicity and the environment. Springer, BaselCrossRef
Zurück zum Zitat UN: 200,000 die each year from pesticide poisoning | News | Al Jazeera UN: 200,000 die each year from pesticide poisoning | News | Al Jazeera
Zurück zum Zitat World Health Organization (2017) Prioritization of pathogens to guide discovery, research and development of new antibiotics for drug resistant bacterial infections, including tuberculosis. WHO, Geneva World Health Organization (2017) Prioritization of pathogens to guide discovery, research and development of new antibiotics for drug resistant bacterial infections, including tuberculosis. WHO, Geneva
Zurück zum Zitat World Health Organization (2019) Water, sanitation, hygiene and health. A primer for health professionals. WHO, Geneva, p 40 World Health Organization (2019) Water, sanitation, hygiene and health. A primer for health professionals. WHO, Geneva, p 40
Metadaten
Titel
Aptamer Mediated Sensing of Environmental Pollutants Utilizing Peroxidase Mimic Activity of NanoZymes
verfasst von
Neeti Kalyani
Bandhan Chatterjee
Tarun Kumar Sharma
Copyright-Jahr
2021
DOI
https://doi.org/10.1007/978-3-030-68230-9_5