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Microsystem Technologies
Erschienen in: Microsystem Technologies 6/2020

21.12.2019 | Technical Paper

Automated manipulation of zebrafish embryos using an electrothermal microgripper

verfasst von: Zhuo Zhang, Yueqing Yu, Peng Song, Yatao Zhang, Dongming Tian, Huipeng Zhang, Hongmiao Wei, Mingyu Cui, Guoning Si, Xuping Zhang

Erschienen in: Microsystem Technologies | Ausgabe 6/2020

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Abstract

We present the first report on automated micro-manipulation of zebrafish embryos using an electrothermally-actuated microgripper. A five-bar linkage compliant microgripper, driven by a V-shaped electrothermal micro-actuator, is designed based on topological optimization. The electrothermally-actuated microgripper is fabricated, tested, and then integrated into a robotic micromanipulation system. The semi-automated manipulation of a single zebrafish embryo, as well as a series of comparison experiments, is carried out. Experimental results demonstrate that the microgripper has reliable capability of picking, moving, holding and releasing the zebrafish embryo. Specifically, it performs fairly well in immobilizing and limiting the excessive deformation of the embryo. Finally, based on teaching, the whole process of zebrafish embryo microinjection is programed and performed automatically, thus demonstrating great strengths and performance of the microgripper in zebrafish embryo micro-manipulation.
Vorheriger Artikel Impact of stress effect on triple material gate step-FinFET with DC and AC analysis
Nächster Artikel Effects of bonding position on bending behavior of flexible anisotropic conductive film packages considering neutral surface

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Metadaten
Titel
Automated manipulation of zebrafish embryos using an electrothermal microgripper
verfasst von
Zhuo Zhang
Yueqing Yu
Peng Song
Yatao Zhang
Dongming Tian
Huipeng Zhang
Hongmiao Wei
Mingyu Cui
Guoning Si
Xuping Zhang
Publikationsdatum
21.12.2019
Verlag
Springer Berlin Heidelberg
Erschienen in
Microsystem Technologies / Ausgabe 6/2020
Print ISSN: 0946-7076
Elektronische ISSN: 1432-1858
DOI
https://doi.org/10.1007/s00542-019-04728-1

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