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2021 | OriginalPaper | Buchkapitel

Bayesian Deep Active Learning for Medical Image Analysis

verfasst von : Biraja Ghoshal, Stephen Swift, Allan Tucker

Erschienen in: Artificial Intelligence in Medicine

Verlag: Springer International Publishing

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Abstract

Deep Learning has achieved a state-of-the-art performance in medical imaging analysis but requires a large number of labelled images to obtain good adequate performance. However, such labelled images are costly to acquire in time, labour, and human expertise. We propose a novel practical Bayesian Active Learning approach using Dropweights and overall bias-corrected uncertainty measure to suggest which unlabelled image to annotate. Experiments were done on Brain Tumour MR images, Microscopic Cell Image classification, Fluoro-chromogenic cytokeratin-Ki-67 double staining cancer images and Retina fundus image segmentation tasks. We demonstrate that our active learning technique is equally successful or better than other existing active learning approaches in high dimensional data to reduce the image labelling effort significantly. We believe Bayesian deep active learning framework with very few annotated samples in a practical way will benefit clinicians to obtain fast and accurate image annotation with confidence.

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Literatur
1.
Zurück zum Zitat Aggarwal, C., Kong, X., Gu, Q., Han, J., Yu, P.: Active learning: a survey. In: Aggarwal, C.C. (ed.) Data Classification: Algorithms and Applications, pp. 571–606. CRC Press (2014) Aggarwal, C., Kong, X., Gu, Q., Han, J., Yu, P.: Active learning: a survey. In: Aggarwal, C.C. (ed.) Data Classification: Algorithms and Applications, pp. 571–606. CRC Press (2014)
2.
Zurück zum Zitat Cheng, J., et al.: Retrieval of brain tumors by adaptive spatial pooling and fisher vector representation. PLoS ONE 11(6), e0157112 (2016)CrossRef Cheng, J., et al.: Retrieval of brain tumors by adaptive spatial pooling and fisher vector representation. PLoS ONE 11(6), e0157112 (2016)CrossRef
3.
Zurück zum Zitat Cheng, J., et al.: Enhanced performance of brain tumor classification via tumor region augmentation and partition. PLoS ONE 10(10), e0140381 (2015)CrossRef Cheng, J., et al.: Enhanced performance of brain tumor classification via tumor region augmentation and partition. PLoS ONE 10(10), e0140381 (2015)CrossRef
4.
Zurück zum Zitat Di Scandalea, M.L., Perone, C.S., Boudreau, M., Cohen-Adad, J.: Deep active learning for axon-myelin segmentation on histology data. arXiv preprint arXiv:1907.05143 (2019) Di Scandalea, M.L., Perone, C.S., Boudreau, M., Cohen-Adad, J.: Deep active learning for axon-myelin segmentation on histology data. arXiv preprint arXiv:​1907.​05143 (2019)
5.
Zurück zum Zitat Gal, Y., Ghahramani, Z.: Dropout as a Bayesian approximation: representing model uncertainty in deep learning. In: 33rd International Conference on Machine Learning, ICML 2016, vol. 3, pp. 1651–1660 (2016) Gal, Y., Ghahramani, Z.: Dropout as a Bayesian approximation: representing model uncertainty in deep learning. In: 33rd International Conference on Machine Learning, ICML 2016, vol. 3, pp. 1651–1660 (2016)
6.
7.
Zurück zum Zitat Ghoshal, B., Lindskog, C., Tucker, A.: Estimating uncertainty in deep learning for reporting confidence: an application on cell type prediction in testes based on proteomics. In: Berthold, M.R., Feelders, A., Krempl, G. (eds.) IDA 2020. LNCS, vol. 12080, pp. 223–234. Springer, Cham (2020). https://doi.org/10.1007/978-3-030-44584-3_18CrossRef Ghoshal, B., Lindskog, C., Tucker, A.: Estimating uncertainty in deep learning for reporting confidence: an application on cell type prediction in testes based on proteomics. In: Berthold, M.R., Feelders, A., Krempl, G. (eds.) IDA 2020. LNCS, vol. 12080, pp. 223–234. Springer, Cham (2020). https://​doi.​org/​10.​1007/​978-3-030-44584-3_​18CrossRef
8.
Zurück zum Zitat Ghoshal, B., Tucker, A., Sanghera, B., Lup Wong, W.: Estimating uncertainty in deep learning for reporting confidence to clinicians in medical image segmentation and diseases detection. Comput. Intell. (2020) Ghoshal, B., Tucker, A., Sanghera, B., Lup Wong, W.: Estimating uncertainty in deep learning for reporting confidence to clinicians in medical image segmentation and diseases detection. Comput. Intell. (2020)
9.
Zurück zum Zitat Houlsby, N., Huszár, F., Ghahramani, Z., Lengyel, M.: Bayesian active learning for classification and preference learning. Stat 1050, 24 (2011) Houlsby, N., Huszár, F., Ghahramani, Z., Lengyel, M.: Bayesian active learning for classification and preference learning. Stat 1050, 24 (2011)
10.
Zurück zum Zitat Ma, J., et al.: How distance transform maps boost segmentation CNNs: an empirical study. In: Arbel, T., Ayed, I.B., de Bruijne, M., Descoteaux, M., Lombaert, H., Pal, C. (eds.) Medical Imaging with Deep Learning. Proceedings of Machine Learning Research, vol. 121, pp. 479–492. PMLR (2020). http://proceedings.mlr.press/v121/ma20b.html Ma, J., et al.: How distance transform maps boost segmentation CNNs: an empirical study. In: Arbel, T., Ayed, I.B., de Bruijne, M., Descoteaux, M., Lombaert, H., Pal, C. (eds.) Medical Imaging with Deep Learning. Proceedings of Machine Learning Research, vol. 121, pp. 479–492. PMLR (2020). http://​proceedings.​mlr.​press/​v121/​ma20b.​html
12.
Zurück zum Zitat Ren, P., Xiao, Y., Chang, X., Huang, P.Y., Li, Z., Chen, X., Wang, X.: A survey of deep active learning. arXiv preprint arXiv:2009.00236 (2020) Ren, P., Xiao, Y., Chang, X., Huang, P.Y., Li, Z., Chen, X., Wang, X.: A survey of deep active learning. arXiv preprint arXiv:​2009.​00236 (2020)
13.
Zurück zum Zitat Settles, B.: Active learning literature survey. Computer Sciences Technical report 1648, University of Wisconsin, Department of Computer Science (2009) Settles, B.: Active learning literature survey. Computer Sciences Technical report 1648, University of Wisconsin, Department of Computer Science (2009)
14.
Zurück zum Zitat Staal, J., Abramoff, M.D., Niemeijer, M., Viergever, M.A., Van Ginneken, B.: Ridge-based vessel segmentation in color images of the retina. IEEE Trans. Med. Imaging 23(4), 501–509 (2004)CrossRef Staal, J., Abramoff, M.D., Niemeijer, M., Viergever, M.A., Van Ginneken, B.: Ridge-based vessel segmentation in color images of the retina. IEEE Trans. Med. Imaging 23(4), 501–509 (2004)CrossRef
15.
Zurück zum Zitat Valkonen, M., et al.: Cytokeratin-supervised deep learning for automatic recognition of epithelial cells in breast cancers stained for ER, PR, and Ki-67. IEEE Trans. Med. Imaging 39(2), 534–542 (2019)CrossRef Valkonen, M., et al.: Cytokeratin-supervised deep learning for automatic recognition of epithelial cells in breast cancers stained for ER, PR, and Ki-67. IEEE Trans. Med. Imaging 39(2), 534–542 (2019)CrossRef
17.
Zurück zum Zitat Wang, K., Zhang, D., Li, Y., Zhang, R., Lin, L.: Cost-effective active learning for deep image classification. IEEE Trans. Circ. Syst. Video Technol. 27(12), 2591–2600 (2016)CrossRef Wang, K., Zhang, D., Li, Y., Zhang, R., Lin, L.: Cost-effective active learning for deep image classification. IEEE Trans. Circ. Syst. Video Technol. 27(12), 2591–2600 (2016)CrossRef
Metadaten
Titel
Bayesian Deep Active Learning for Medical Image Analysis
verfasst von
Biraja Ghoshal
Stephen Swift
Allan Tucker
Copyright-Jahr
2021
DOI
https://doi.org/10.1007/978-3-030-77211-6_4