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Über dieses Buch

The generation of tridimensional tissues, assembled from scaffolding materials populated with biologically functional cells, is the great challenge and hope of tissue bioengineering and regenerative medicine. The generation of biomaterials capable of harnessing the immune system has been particularly successful. This book provides a comprehensive view of how immune cells can be manipulated to suppresses inflammation, deliver vaccines, fight cancer cells, promote tissue regeneration or inhibit blood clotting and bacterial infections by functionally engineered biomaterials. However, long-lived polymers, such as those employed in orthopedic surgery or vascular stents, can often induce an immune reaction to their basic components. As a result, this book is also an important step towards coming to understand how to manipulate biomaterials to optimize their beneficial effects and downplay detrimental immune responses.

Inhaltsverzeichnis

Frontmatter

2015 | OriginalPaper | Buchkapitel

1. Role of Mesenchymal Stem Cells, Macrophages, and Biomaterials During Myocardial Repair

Isabella Pallotta, Emily A. Wrona, Bruce Sun, Donald O. Freytes

2015 | OriginalPaper | Buchkapitel

2. The Role of Macrophages in the Foreign Body Response to Implanted Biomaterials

Tony Yu, Valerie J. Tutwiler, Kara Spiller

2015 | OriginalPaper | Buchkapitel

3. Integrating Tissue Microenvironment with Scaffold Design to Promote Immune-Mediated Regeneration

Kaitlyn Sadtler, Franck Housseau, Drew Pardoll, Jennifer H. Elisseeff

2015 | OriginalPaper | Buchkapitel

4. Advances in Molecular Design of Polymer Surfaces with Antimicrobial, Anticoagulant, and Antifouling Properties

Marek W. Urban

2015 | OriginalPaper | Buchkapitel

5. Layer-by-Layer Coatings as Infection-Resistant Biomaterials

Svetlana A. Sukhishvili

2015 | OriginalPaper | Buchkapitel

6. Nature-Inspired Multifunctional Host Defense Peptides with Dual Antimicrobial-Immunomodulatory Activities

Jasmeet Singh Khara, Pui Lai Rachel Ee

2015 | OriginalPaper | Buchkapitel

7. Biomaterials-Based Strategies in Blood Substitutes

Anirban Sen Gupta

2015 | OriginalPaper | Buchkapitel

8. Biomaterials-Based Immunomodulation of Dendritic Cells

Evelyn Bracho-Sanchez, Jamal S. Lewis, Benjamin G. Keselowsky

2015 | OriginalPaper | Buchkapitel

9. Nanosystems for Immunotherapeutic Drug Delivery

Alex Schudel, Michael C. Bellavia, Susan N. Thomas

2015 | OriginalPaper | Buchkapitel

10. Biomaterial-Based Modulation of Cancer

Fnu Apoorva, Ankur Singh

2015 | OriginalPaper | Buchkapitel

11. Targeting Liposomes to Immune Cells

Matthew Levy, Deborah Palliser

2015 | OriginalPaper | Buchkapitel

12. Integrated Biomaterial Composites for Accelerated Wound Healing

Viness Pillay, Pradeep Kumar, Yahya E. Choonara

2015 | OriginalPaper | Buchkapitel

13. Adverse Effects of By-products from Polymers Used for Joint Replacement

Tzu-Hua Lin, Jukka Pajarinen, Florence Loi, Taishi Sato, Changchun Fan, Zhenyu Yao, Stuart Goodman

2015 | OriginalPaper | Buchkapitel

14. Artificial Antigen-Presenting Cells: Biomimetic Strategies for Directing the Immune Response

Randall A. Meyer, Jordan J. Green

Backmatter

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