The paper reports the significance of bilayer lipid membranes on a solid support (sBLM) for the construction of biosensors. The methods of formation of lipid membranes on different solid supports including different metals (silver, gold, stainless steel), agar and conducting polymers are presented. Several examples of the application of electrostriction and dielectric relaxation methods for the study of mechanical properties and dynamics of solid supported bilayers have been shown. We demonstrated that these methods are usefull for determination of the binding of enzymes and antibodies to sBLM and for study physical properties of modified supported membranes.
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- Biosensors Based on Solid Supported Lipid Bilayers and Their Physical Properties
- Springer Netherlands
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