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Cellulose

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31.01.2021 | Original Research

Carbazate functionalized cellulose beads as potential scavengers specific for carbonylated proteins

verfasst von: Lanli Huang, Xiuqiong Zhou, Xianjing Feng, Jieou Nong, Guohua Yan, Li Zheng, Ming Gao

Erschienen in: Cellulose | Ausgabe 5/2021

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Abstract

Scavenging carbonylated proteins that are toxic substances inducing various diseases attract the most attention in the field of blood purification. In our study, functionalized cellulose beads modified by carbazate groups as affinity ligands of carbonyls were prepared for specific scavenging of carbonylated proteins based on the carbazate-aldehyde/ ketone reaction. Results showed that the carbazate-functionalized cellulose beads with different degrees of substitution (DS) maintained the original multi-porous structure with the diameter of about 50 μm and thermal stability. Spectroscopic and gel electrophoresis analysis indicated that the modified cellulose beads could effectively scavenge carbonylated proteins and the scavenging effects increased with the increase of DS. Thus, the carbazate functionalized cellulose beads may be developed as fillers in the column for the scavenging of carbonylated proteins.

Vorheriger Artikel Making security glazing from modified TEMPO oxidized nanofibers and poly vinylbutyral

Nächster Artikel A novel waste paper cellulose-based Cu-MOF hybrid material threaded by PSS for lithium extraction with high adsorption capacity and selectivity

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Aldini G, Dalle-Donne I, Facino RM, Milzani A, Carini M (2007) Intervention strategies to inhibit protein carbonylation by lipoxidation-derived reactive carbonyls. Med Res Rev 27:817–868. https://doi.org/10.1002/med.20073CrossRefPubMed

Bethell GS, Ayers JS, Hearn MTW, Hancock WS (1987) Investigation of the activation of various insoluble polysaccharides with 1,1′-carbonyldiimidazole and of the properties of the activated matrices. J Chromatogr A 219:361–371. https://doi.org/10.1016/S0021-9673(00)80379-9CrossRef

Baker G, Matveychuk D, MacKenzie EM, Holt A, Wang Y, Kar S (2019) Attenuation of the effects of oxidative stress by the MAO-inhibiting antidepressant and carbonyl scavenger phenelzine. Chem Biol Interact 304:139–147. https://doi.org/10.1016/j.cbi.2019.03.003CrossRefPubMed

Chen J et al (2017) Non-ionic macroporous polystyrene adsorbents for removal of serum toxins in liver failure by hemoperfusion Artif Cells Nanomed. Biotechnol 45:174–183. https://doi.org/10.3109/21691401.2016.1138494CrossRef

Dibbert N, Krause A, Rios-Camacho JC, Gruh I, Kirschning A, Drager G (2016) A synthetic toolbox for the in situ formation of functionalized homo- and heteropolysaccharide-based hydrogel libraries. Chemistry 22:18777–18786. https://doi.org/10.1002/chem.201603748CrossRefPubMed

Fedorova M, Bollineni RC, Hoffmann R (2014) Protein carbonylation as a major hallmark of oxidative damage: update of analytical strategies. Mass Spectrom Rev 33:79–97. https://doi.org/10.1002/mas.21381CrossRefPubMed

Fernando N et al (2016) Protein carbonyl as a biomarker of oxidative stress in severe leptospirosis, and its usefulness in differentiating leptospirosis from dengue infections. PLoS ONE 11:e0156085. https://doi.org/10.1371/journal.pone.0156085CrossRefPubMedPubMedCentral

Girardot T, Schneider A, Rimmelé T (2019) Blood purification techniques for sepsis and septic aki. Semin Nephrol 39:505–514. https://doi.org/10.1016/j.semnephrol.2019.06.010CrossRefPubMed

Hauck AK, Huang Y, Hertzel AV, Bernlohr DA (2019) Adipose oxidative stress and protein carbonylation. J Biol Chem 294:1083–1088CrossRef

Hecker M, Wagner AH (2018) Role of protein carbonylation in diabetes. J Inherit Metab Dis 41:29–38. https://doi.org/10.1007/s10545-017-0104-9CrossRefPubMed

Kolawole TA, Ilochi ON, Oluwatayo BO, Chuemere AN, Dapper DV (2019) Tissue protein carbonylation in aging: A strategic analysis of age-related protein modification. J Adv Med Pharm Sci 20:1–5. https://doi.org/10.9734/jamps/2019/v20i330111CrossRef

Kolmel DK, Kool ET (2017) Oximes and hydrazones in bioconjugation: mechanism and catalysis. Chem Rev 117:10358–10376. https://doi.org/10.1021/acs.chemrev.7b00090CrossRefPubMedPubMedCentral

Kecili R, Nivhede D, Billing J, Leeman M, Sellergren B, Yilmaz E (2012) Removal of acrolein from active pharmaceutical ingredients using aldehyde scavengers. Org Process Res Dev 16:1225–1229. https://doi.org/10.1021/op3000459CrossRef

Li Y, Han M, Wang Y, Liu Q, Zhao W, Su B, Zhao C (2018) A mussel-inspired approach towards heparin-immobilized cellulose gel beads for selective removal of low density lipoprotein from whole blood. Carbohydr Polym 202:116–124. https://doi.org/10.1016/j.carbpol.2018.08.118CrossRefPubMed

Lanzillotto M, Konnert L, Lamaty F, Martinez J, Colacino E (2015) Mechanochemical 1,1′-carbonyldiimidazole-mediated synthesis of carbamates. ACS Sustain Chem Eng 3:2882–2889. https://doi.org/10.1021/acssuschemeng.5b0081CrossRef

Malik DJ et al (2009) Synthesis and characterization of size-selective nanoporous polymeric adsorbents for blood purification. Sep Purif Technol 66:578–585. https://doi.org/10.1016/j.seppur.2009.01.016CrossRef

Ngamcherdtrakul W, Morry J, Sangvanich T, Reda M, Bejan DS, Fryxell GE, Yantasee W (2019) Removal of a gadolinium based contrast agent by a novel sorbent hemoperfusion in a chronic kidney disease (ckd) rodent model. Sci Rep 9:709. https://doi.org/10.1038/s41598-018-37348-2CrossRefPubMedPubMedCentral

Oommen OP, Wang SJ, Kisiel M, Sloff M, Hilborn J, Varghese OP (2013) Smart design of stable extracellular matrix mimetic hydrogel: Synthesis, characterization, and in vitro and in vivo evaluation for tissue engineering. Adv Funct Mater 23:1273–1280. https://doi.org/10.1002/adfm.201201698CrossRef

Puleo DA, Kissling RA, Sheu MS (2002) A technique to immobilize bioactive proteins, includingbone morphogenetic protein-4 (BMP-4), on titanium alloy. Biomaterials 23(9):2079–2087. https://doi.org/10.1016/s0142-9612(01)00339-8CrossRefPubMed

Peng B et al (2019) Tuned cationic dendronized polymer: Molecular scavenger for rheumatoid arthritis treatment. Angew Chem Int Ed Engl 58:4254–4258. https://doi.org/10.1002/anie.201813362CrossRefPubMed

Rani V, Deep G, Singh RK, Palle K, Yadav UCS (2016) Oxidative stress and metabolic disorders: pathogenesis and therapeutic strategies. Life Sci 148:183–193. https://doi.org/10.1016/j.lfs.2016.02.002CrossRefPubMed

Rocha I, Ferraz N, Mihranyan A, Strømme M, Lindh J (2018) Sulfonated nanocellulose beads as potential immunosorbents. Cellulose 25:1899–1910. https://doi.org/10.1007/s10570-018-1661-2CrossRef

Ruan CQ, Stromme M, Lindh J (2018) Preparation of porous 2,3-dialdehyde cellulose beads crosslinked with chitosan and their application in adsorption of Congo red dye. Carbohydr Polym 181:200–207. https://doi.org/10.1016/j.carbpol.2017.10.072CrossRefPubMed

Su X, Aprahamian I (2014) Hydrazone-based switches, metallo-assemblies and sensors. Chem Soc Rev 43:1963–1981. https://doi.org/10.1039/c3cs60385gCrossRefPubMed

Sharma PK, Singh Y (2019) Glyoxylic hydrazone linkage-based peg hydrogels for covalent entrapment and controlled delivery of doxorubicin. Biomacromol 20:2174–2184. https://doi.org/10.1021/acs.biomac.9b00020CrossRef

Yu Y (2013) Adsorbents in blood purification: from lab search to clinical therapy. Chin Sci Bul 558:4357–4361CrossRef

Yang YF, Gao M, Zhou B, Cai PA, Larsson TE, Zhao JM, Bowden TM (2020) Weak acidic stable carbazate modified cellulose membranes target for scavenging carbonylated proteins in hemodialysis. Carbohydr polym 231:115727. https://doi.org/10.1016/j.carbpol.2019.115727CrossRefPubMed

Yang XF et al (2017) Highly efficient self-healable and dual responsive cellulose-based hydrogels for controlled release and 3d cell culture. Adv Funct Mater. https://doi.org/10.1002/adfm.201703174CrossRefPubMedPubMedCentral

Yamamoto S et al (2018) Adsorption of protein-bound uremic toxins through direct hemoperfusion with hexadecyl-immobilized cellulose beads in patients undergoing hemodialysis. Artif Organs 42:88–93. https://doi.org/10.1111/aor.12961CrossRefPubMed

Zhou B et al. (2020) Carbazate modified dextrans as scavengers for carbonylated proteins. Carbohydrate Polymers 232: 115802. http://www.sciencedirect.com/science/article/pii/S0144861719314705

Titel: Carbazate functionalized cellulose beads as potential scavengers specific for carbonylated proteins
verfasst von: Lanli Huang
Xiuqiong Zhou
Xianjing Feng
Jieou Nong
Guohua Yan
Li Zheng
Ming Gao
Publikationsdatum: 31.01.2021
Verlag: Springer Netherlands
Erschienen in: Cellulose / Ausgabe 5/2021
Print ISSN: 0969-0239
Elektronische ISSN: 1572-882X
DOI: https://doi.org/10.1007/s10570-020-03659-9

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