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01.06.2015 | Research Paper

Carboxymethylated chitosan-stabilized copper nanoparticles: a promise to contribute a potent antifungal and antibacterial agent

verfasst von: Sangeeta Tantubay, Sourav K. Mukhopadhyay, Himani Kalita, Suraj Konar, Satyahari Dey, Amita Pathak, Panchanan Pramanik

Erschienen in: Journal of Nanoparticle Research | Ausgabe 6/2015

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Abstract

Carboxymethylated chitosan (CMC)-stabilized copper nanoparticles (Cu-NPs) have been synthesized via chemical reduction of copper(II)–CMC complex in aqueous medium by hydrazine under microwave irradiation in ambient atmosphere. Structural morphology, phase, and chemical compositions of CMC-stabilized Cu-NPs (CMC–Cu-NPs) have been analyzed through high-resolution transmission electron microscopy, field emission scanning electron microscopy, X-ray diffraction, and X-ray photoelectron spectroscopy. Antifungal and antibacterial activities of CMC–Cu-NPs have been evaluated against Candida tropicalis and Escherichia coli through agar well diffusion method, broth microdilution assay, live–dead assay, and microscopic observation. Antimicrobial activity of spherical CMC–Cu-NPs (~4–15 nm of diameters) has been observed to be significant for both C. tropicalis and E. coli. The cytotoxicity study indicates that CMC–Cu-NPs have no significant toxic effect against normal cell line, L929.

Vorheriger Artikel Stable and solid pellets of functionalized multi-walled carbon nanotubes produced under high pressure and temperature

Nächster Artikel Effect of reduction enhancer on a radiolytic synthesis of carbon-supported Pt–Cu nanoparticles and their structural and electrochemical properties

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Titel: Carboxymethylated chitosan-stabilized copper nanoparticles: a promise to contribute a potent antifungal and antibacterial agent
verfasst von: Sangeeta Tantubay
Sourav K. Mukhopadhyay
Himani Kalita
Suraj Konar
Satyahari Dey
Amita Pathak
Panchanan Pramanik
Publikationsdatum: 01.06.2015
Verlag: Springer Netherlands
Erschienen in: Journal of Nanoparticle Research / Ausgabe 6/2015
Print ISSN: 1388-0764
Elektronische ISSN: 1572-896X
DOI: https://doi.org/10.1007/s11051-015-3047-9

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