Abstract
This study explored the effect of waterproofness, by using five commercially available polymers, on the clinical efficacy and irritation potential of sunscreen products. A marketed o/w SPF 30 sunscreen cream was selected as the model vehicle. To achieve the SPF 30 of the sunscreen formula, 7.5% octyl methoxycinnamate (Parsol MCX), 4.0% oxybenzone, and 3.0% octyl salicylate were the sunscreens chosen. Ganex V220, Pemulen TR1, PVP K-90, Polymer X, and Carboset XPD1616 were the polymers chosen in the study. The study results suggested that the release of sunscreens from the waterproof formula is the rate-limiting step in absorption process. It also suggested that the waterproofness may provide an alternative way of reducing the irritation potential of the sunscreen products, without detriment to its clinical efficacy.
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© 1991 Springer Science+Business Media New York
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Wang, J.C.T., Liu, JC., Dole, V., Tseng, Cy. (1991). Effects of Waterproofness on the Clinical Efficacy and Irritation Potential of Sunscreen Products. In: Gebelein, C.G., Cheng, T.C., Yang, V.C. (eds) Cosmetic and Pharmaceutical Applications of Polymers. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3858-5_8
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DOI: https://doi.org/10.1007/978-1-4615-3858-5_8
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-6722-2
Online ISBN: 978-1-4615-3858-5
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