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Identification of Fungicide Targets in Pathogenic Fungi

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Physiology and Genetics

Part of the book series: The Mycota ((MYCOTA,volume 15))

Abstract

The rapid emergence of fungicide resistance has brought a strong demand for plant protectants with a new mode of action. One of the challenges for modern plant pathology research is the identification of genes and gene products essential for the establishment of pathogenic interactions between host and pathogen. Genome-wide technologies, such as transcriptomics, metabolomics, and proteomics represent a new opportunity to identify such targets in phytopathogenic fungi. This chapter reviews genome-wide approaches that have emerged in the post-genomics era, e.g. comparative genomics and gene expression profiling experiments such as microarray-based transcriptional profiling, serial analysis of gene expression, and massively parallel signature sequencing. It also discusses prospects for exploiting these modern technologies for the development of plant protectants and system biology.

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Authors and Affiliations

  1. Institut für Biotechnologie und Wirkstoff-Forschung e.V., Institute for Biotechnology and Drug Research, Erwin-Schrödinger-Strasse 56, 67663, Kaiserslautern, Germany

    Andrew J. Foster

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  1. Andrew J. Foster
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  2. Eckhard Thines
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Correspondence to Andrew J. Foster .

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Editors and Affiliations

  1. Inst. Biotechnologie und, TU Kaiserslautern, Erwin-Schrödinger-Str. 56, Kaiserslautern, 67663, Germany

    Timm Anke

  2. MIP Pharma GmbH, Mühlstr. 50, St.Ingbert, 66386, Germany

    Daniela Weber

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Foster, A.J., Thines, E. (2009). Identification of Fungicide Targets in Pathogenic Fungi. In: Anke, T., Weber, D. (eds) Physiology and Genetics. The Mycota, vol 15. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-00286-1_11

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