Zusammenfassung
Schlafstörungen sind häufige Beschwerden älterer Menschen. Die Therapie geriatrischer Patienten sollte sich anhand einer differenzierten Erhebung der nächtlichen Probleme an den spezifischen Schlafstörungen orientieren. Hier stehen vor allem Einschlafstörungen (Insomnie), Durchschlafstörungen und Störungen der Tagesrhythmik im Vordergrund, gefolgt von den Symptomen eines Restless-Legs-Syndroms, das häufig bei über 65-Jährigen und bei zunehmenden Komorbiditäten auftritt. Bei einer Tagesschläfrigkeit, oft bedingt durch ein obstruktives Schlaf-Apnoe-Syndrom, muss ggf. mit einer CPAP-Therapie behandelt werden. Eine allgemeine abendliche oder nächtliche Unruhe geriatrischer Patienten (häufig bei Patienten mit Demenz) sollte von Schlafstörungen und Störungen der Tagesrhythmik abgegrenzt werden, da die Behandlung unterschiedlich ist. Eine differenzierte Betrachtung nächtlicher Störungen in der Neurogeriatrie ist deshalb essentielle Voraussetzung jeglicher psychopharmakologischer Therapie.
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Literatur
Allen RP, Walter AS, Montaplaisir J, Hening W, Myers A, Bell TJ, Ferini-Strambi L (2005) Restless legs syndrome prevalence and impact: rest general population study. Arch Intern Med 165(11):1286–1292
Allen R, Oertel W, Walters A, Benes H, Schollmayer E, Grieger F, Moran K, Kohnen R (2013) Relation of the international restless legs syndrome study group rating scale with the clinical global impression severity scale, the restless legs syndrome 6-item questionnaire, and the restless legs syndrome-quality of life questionnaire. Sleep Med 14(12):1375–1380
Allen RP, Picchietti DL, Garcia-Borreguero D, Ondo WG, Walter AS, Winkelman JW, Zucconi M, Ferri R, Trenkwalder C, Lee HB (2014) Restless legs syndrome/Willis-Ekbom disease diagnostic criteria: updated International Restless Legs Syndrome Study Group (IRLSSG) consensus criteria–history, rationale, description, and significance. Sleep Med 15(8):860–873
Ancoli Israel S, Martin JL, Kripke DF, Marler M, Klauber MR (2002) Effect of light treatment on sleep and circadian rhythms in demented nursing home patients. J Am Geriatr Soc 50(2):282–289
Ancoli-Israel S, Kripke DF, Klauber MR, Mason WJ, Fell R, Kaplan O (1991) Sleep-disordered breathing in community-dwelling elderly. Sleep 14(6):486–495
Ancoli-Israel S, Ayalon L, Salzman C (2008) Sleep in the elderly: normal variations and common sleep disorders. Harv Rev Psychiatry 16(5):279–286
Berger K, Luedemann J, Trenkwalder C, John U, Kessler C (2004) Sex and the risk of restless legs syndrome in the general population. Arch Intern Med 164(2):196–202
Bjornsdottir E, Keenan BT, Eysteinsdottir B, Arnadottir ES, Janson C, Gislason T, Sigurdsson JF, Kuna ST, Pack AI, Benediktsdottir B (2015) Quality of life among untreated sleep apnea patients compared with the general population and changes after treatment with positive airway pressure. J Sleep Res 24(3):328–338
Bloom HG, Ahmed I, Alessi CA, Ancoli-Israel S, Buysse DJ, Kryger MH, Phillips BA, Thorpy MJ, Vitiello MV, Zee PC (2009) Evidence-based recommendations for the assessment and management of sleep disorders in older persons. J Am Geriatr Soc 57(5):761–789
Buysse DJ, Reynolds CF 3rd, Monk TH, Berman SR, Kupfer DJ (1989) The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Res 28(2):193–213
Cao W, Edery I (2015) A novel pathway for sensory-mediated arousal involves splicing of an intron in the period clock gene. Sleep 38(1):41–51
Chaperon CM, Farr LA, LoChiano E (2007) Sleep disturbance of residents in a continuing care retirement community. J Gerontol Nurs 33(10):21–28 (quiz 30–31)
Cipriani G, Lucetti C, Danti S, Nuti A (2015) Sleep disturbances and dementia. Psychogeriatr 15(1):65–74
Cochen V, Arbus C, Soto ME, Villars H, Tiberge M, Montemayor T, Hein C, Veccherini MF, Onen SH, Ghorayeb I, Verny M, Fitten LJ, Savage J, Dauvilliers Y, Vellas B (2009) Sleep disorders and their impacts on healthy, dependent, and frail older adults. J Nutr Health Aging 13(4):322–329
Connor JR, Patton SM, Oexle K, Allen RP (2017) Iron and restless legs syndrome: treatment, genetics and pathophysiology. Sleep Med 31:61–70
Cooke JR, Ancoli-Israel S (2011) Normal and abnormal sleep in the elderly. Handb Clin Neurol 98:653–665
DGSM (2009) S3-Leitlinie Nicht erholsamer Schlaf/Schlafstörungen. Somnologie – Schlafforschung und Schlafmedizin 13(S1):1–160 (ICF 2005)
Duffy JF, Zitting KM, Chinoy ED (2015) Aging and circadian rhythms. Sleep Med Clin 10(4):423–434
Foley DJ, Monjan AA, Brown SL, Simonsick EM, Wallace RB, Blazer DG (1995) Sleep complaints among elderly persons: an epidemiologic study of three communities. Sleep 18(6):425–432
Frei P, Mohler E, Roosli M (2014) Effect of nocturnal road traffic noise exposure and annoyance on objective and subjective sleep quality. Int J Hyg Environ Health 217(2–3):188–195
Frohnhofen H, Schlitzer J (2014) Sleep and sleep disorders in the elderly: Part 1: epidemiology and diagnostics. Z Gerontol Geriatr 47(6):527–537
Furihata R, Hall MH, Stone KL, Ancoli-Israel S, Smagula SF, Cauley JA, Kaneita Y, Uchiyama M, Buysse DJ (2017) An aggregate measure of sleep health is associated with prevalent and incident clinically significant depression symptoms among community-dwelling older women. Sleep 40(3):1–11
Gagnon C, Bélanger L, Ivers H, Morin CM (2013) Validation of the Insomnia Severity Index in primary care. J Am Board Fam Med 26(6):701–710
Garbarino S, Lanteri P, Durando P, Magnavita N, Sannita WG (2016) Co-morbidity, mortality, quality of life and the healthcare/welfare/social costs of disordered sleep: a rapid review. Int J Environ Res Public Health 13(8):1–15
Garcia-Borreguero D, Cano-Pumarega I (2017) New concepts in the management of restless legs syndrome. BMJ 356:j104
Guo S, Huang J, Jiang H, Han C, Li J, Xu X, Zhang G, Lin Z, Xiong N, Wang T (2017) Restless legs syndrome: from pathophysiology to clinical diagnosis and management. Front Aging Neurosci 9, Article 171:1–14
Happe S, Vennemann M, Evers S, Berger K (2008) Treatment wish of individuals with known and unknown restless legs syndrome in the community. J Neurol 255(9):1365–1371
Hogl B, Stefani A, Videnovic A (2018) Idiopathic REM sleep behaviour disorder and neurodegeneration – an update. Nat Rev Neurol 14(1):40–55
Kang K, Park KS, Kim JE, Kim SW, Kim YT, Kim JS, Lee HW (2013) Usefulness of the Berlin questionnaire to identify patients at high risk for obstructive sleep apnea: a population-based door-to-door study. Sleep Breath 17(2):803–810
Kendzerska TB, Smith PM, Brignardello-Petersen R, Leung RS, Tomlinson GA (2014) Evaluation of the measurement properties of the Epworth sleepiness scale: a systematic review. Sleep Med Rev 18(4):321–331
Kohnen R, Martinez-Martin P, Benes H, Trenkwalder C, Högl B, Dunkl E, Walters AS (2016) Validation of the Kohnen Restless Legs Syndrome-Quality of Life instrument. Sleep Med 24:10–17
Kotagal P, Costa M, Wyllie, Wolgamuth B (2002) Paroxysmal nonepileptic events in children and adolescents. Pediatrics 110(4):e46
Lam S, Macina LO (2017) Therapy update for insomnia in the elderly. Consult Pharm 32(10):610–622
Mehmood T Auerbach M, Earley CJ, Allen RP (2014) Response to intravenous iron in patients with iron deficiency anemia (IDA) and restless leg syndrome (Willis-Ekbom disease). Sleep Med 15(12):1473–1476
Mehmood T, Auerbach M, Earley CJ, Allen RP (2017) Sleep in the aging population. Sleep Med Clin 12(1):31–38
Muntean ML, Benes H, Sixel-Döring F, Chaudhuri KR, Suzuki K, Hirata K, Zimmermann J, Trenkwalder C (2016) Clinically relevant cut-off values for the Parkinson’s Disease Sleep Scale-2 (PDSS-2): a validation study. Sleep Med 24:87–92
N.S. Foundation, Sleep in America Poll. 2003. National Sleep Foundation. https://sleepfoundation.org/sites/default/files/2003SleepPollExecSumm.pdf. Zugegriffen: 13. Juli 2016
Pandey S, Bajaj BK, Wadhwa A, Anand KS (2016) Impact of sleep quality on the quality of life of patients with Parkinson’s disease: a questionnaire based study. Clin Neurol Neurosurg 148:29–34
Partinen M (2011) Epidemiology of sleep disorders. Handb Clin Neurol 98:275–314
Phillips B (2016) Obstructive sleep apnea in the elderly. In: Kryger MH, Roth T, Dement WC (Hrsg) Principles and practices of sleep medicine, 6. Aufl. Elsevier, Amsterdam
Porter VR, Buxton WG, Avidan AY (2015) Sleep, cognition and dementia. Curr Psychiatry Rep 17(12):97
Rodriguez JC, Dzierzewski JM, Alessi CA (2015) Sleep problems in the elderly. Med Clin North Am 99(2):431–439
Rothschild-Fuentes B, Roche A, Jiménez-Genchi A, Sánchez-Ferrer JC, Fresan A, Muñoz-Delgado J (2013) Effects of mirtazapine on the sleep wake rhythm of geriatric patients with major depression: an exploratory study with actigraphy. Pharmacopsychiatry 46(2):59–62
Ruwe F, IJzerman-Boon P, Roth T, Zammit G, Ivgy-May N (2016) A phase 2 randomized dose-finding study with Esmirtazapine in patients with primary insomnia. J Clin Psychopharmacol 36(5):457–464
Savaskan E, Bopp-Kistler I, Buerge M, Fischlin R, Georgescu D, Giardini U, Hatzinger M, Hemmeter M, Justiniano I, Kressig RW, Monsch A, Mosimann UP, Mueri R, Munk A, Popp J, Schmid R, Wollmer MA (2014) Recommendations for diagnosis and therapy of Behavioral and Psychological Symptoms in Dementia (BPSD). Praxis (Bern 1994) 103(3):135–148
Schenck CH (2013) Rapid eye movement sleep behavior disorder: current knowledge and future directions. Sleep Med 14(8):699–702
Silva GE, Goodwin JL, Vana KD, Quan SF (2016) Obstructive sleep apnea and quality of life: comparison of the SAQLI, FOSQ, and SF-36 questionnaires. Southwest J Pulm Crit Care 13(3):137–149
Skottheim A, Lövheim H, Isaksson U, Sandman PO, Gustafsson M (2018) Insomnia symptoms among old people in nursing homes. Int Psychogeriatr 30(1):77–85
Talarska D, Kropińska S, Strugała M, Szewczyczak M, Tobis S, Wieczorowska-Tobis K (2017) The most common factors hindering the independent functioning of the elderly at home by age and sex. Eur Rev Med Pharmacol Sci 21(4):775–785
Trenkwalder C, Kohnen R, Högl B, Metta V, Sixel-Döring F, Frauscher B, Hülsmann J, Martinez-Martin P, Chaudhur KR (2011) Parkinson’s disease sleep scale–validation of the revised version PDSS-2. Mov Disord 26(4):644–652
Trenkwalder C, Beneš H, Grote L, García-Borreguero D, Högl B, Hopp M, Bosse B, Oksche A, Reimer K, Winkelmann J, Allen RP, Kohnen R (2013) Prolonged release oxycodone-naloxone for treatment of severe restless legs syndrome after failure of previous treatment: a double-blind, randomised, placebo-controlled trial with an open-label extension. Lancet Neurol 12(12):1141–1150
Trenkwalder C, Winkelmann J, Inoue Y, Paulus W (2015) Restless legs syndrome-current therapies and management of augmentation. Nat Rev Neurol 11(8):434–445
Videnovic A, Golombek D (2013) Circadian and sleep disorders in Parkinson’s disease. Exp Neurol 243:45–56
Wallace DM, Ramos AR, Rundek T (2012) Sleep disorders and stroke. Int J Stroke 7(3):231–242
Walter AS, Frauscher B, Allen R, Benes H, Chaudhuri KR, Garcia-Borreguero D, Lee HB, Picchietti DL, Trenkwalder C, Martinez-Martin P, Stebbins GT, Schrag A (2014) Review of quality of life instruments for the restless legs syndrome/Willis-Ekbom Disease (RLS/WED): critique and recommendations. J Clin Sleep Med 10(12):1351–1357
WHO D (2017) Internationale statistische Klassifikation der Krankheiten und verwandter Gesundheitsprobleme 10. Revision German Modification Version 2018. WHO, Genf
Ylikoski A, Martikainen K, Sieminski M, Partinen M (2015) Parkinson’s disease and insomnia. Neurol Sci 36(11):2003–2010
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Trenkwalder, C., Bartl, M., Sixel-Döring, F. (2019). Schlafstörungen. In: Maetzler, W., Dodel, R., Jacobs, A. (eds) Neurogeriatrie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-57358-7_15
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