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Risk of Transferring Malignant Cells with Transplanted Frozen-Thawed Ovarian Tissue

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Gonadal Tissue Cryopreservation in Fertility Preservation

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Abstract

Although ovarian tissue cryopreservation and transplantation have emerged as a real option to preserve and restore fertility in young cancer patients, there is a legitimate concern regarding the possible presence of malignant cells in the ovarian tissue, which could lead to recurrence of the disease after reimplantation. The present chapter reviews the existing literature on the subject to evaluate the risk of transplanting malignant cells in case of the main malignant indications for ovarian tissue cryopreservation.

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Acknowledgments

The authors thank Mira Hryniuk, B.A., for reviewing the English language of the manuscript.

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Authors and Affiliations

  1. Pôle de Recherche en Gynécologie, Institut de Recherche Expérimentale et Clinique (IREC), Cliniques Universitaires Saint Luc, Avenue Mounier 52, B1.52.02, 1200, Brussels, Belgium

    Marie-Madeleine Dolmans & Michelle Soares

  2. Département de Gynécologie, Cliniques Universitaires Saint-Luc, 1200, Brussels, Belgium

    Marie-Madeleine Dolmans

Authors
  1. Marie-Madeleine Dolmans
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  2. Michelle Soares
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Correspondence to Marie-Madeleine Dolmans .

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Editors and Affiliations

  1. Department of Obstetrics and Gynecology, St. Marianna University School of Medici, Kawasaki, Kanagawa, Japan

    Nao Suzuki

  2. Societe de Recherche pour l'Inferti, Brussels, Belgium

    Jacques Donnez

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Dolmans, MM., Soares, M. (2016). Risk of Transferring Malignant Cells with Transplanted Frozen-Thawed Ovarian Tissue. In: Suzuki, N., Donnez, J. (eds) Gonadal Tissue Cryopreservation in Fertility Preservation. Springer, Tokyo. https://doi.org/10.1007/978-4-431-55963-4_11

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  • DOI: https://doi.org/10.1007/978-4-431-55963-4_11

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  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-55961-0

  • Online ISBN: 978-4-431-55963-4

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