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Single Use Bioreactors: Expressing Protein in Mammalian Cell Suspension

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Cells and Culture

Part of the book series: ESACT Proceedings ((ESACT,volume 4))

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Abstract

Pharmaceutical and biotechnology industries are experiencing increasing pressures with new drug development timelines. As well as securing a “first to market” commercial advantage, the ability to make rapid decisions during the development cycle of new molecules is crucial.

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Notes

  1. 1.

    Reif, O.-W. and Vogt, R. (2006) Innovations in Pharmaceutical Technology, 19, 61–64.

  2. 2.

    Cellexus Technical Note: Low Temperature Accessory – high yields of expressed protein in E.coli.

  3. 3.

    Cellexus Technical Note: Scale-up from a flask to 50 l in a single step using the CellMaker Lite.

  4. 4.

    Osman, et al. (1992) Lonza. Poster: Stirred Tank and Airlift Bioreactors are Interchangeable Systems for Mammalian Cell Culture.

  5. 5.

    Zhang, S., et al. (1992) J. Biotechnol. 25, 289–306.

  6. 6.

    Zhang, S., et al. (1992) J. Biotechnol. 25, 289–306.

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Correspondence to Kevin A. Auton .

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Auton, K.A. (2010). Single Use Bioreactors: Expressing Protein in Mammalian Cell Suspension. In: Noll, T. (eds) Cells and Culture. ESACT Proceedings, vol 4. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-3419-9_12

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