Skip to main content

Surface activity

  • Chapter
Surfactant Systems

Abstract

A surface-active agent is, as the name implies, a compound which will adsorb at an air-water or oil-water interface and at the surface of solids. The structural features of these molecules which are responsible for surface activity are examined in this chapter and some of the factors which influence the extent of adsorption are considered. A study of the adsorption process is of fundamental importance in an understanding of the properties of surface-active compounds since, as we will discuss in later chapters, it is the change in interfacial free energy and surface charge resulting from adsorption which leads to the ability of these compounds to act as emulsifying and suspending agents. A survey of the wide variety of surfactants which are used in pharmaceutical systems is included in the chapter, together with a brief indication of the many and diverse uses of this versatile group of compounds.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 99.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 129.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. G. Némethy and H. S. Sheraga (1962) J. Chem. Phys. 36, 3382.

    Google Scholar 

  2. F. Franks, J. Ravenhill, P. A. Egelstaff and D. I Page (1970) Proc. Roy. Soc.(London) A 319, 189.

    Google Scholar 

  3. I. Danielsson, B. Lindman and L. Odberg (1969) Suomen Kemistilehti 42, 209.

    Google Scholar 

  4. H. Lange(1966) in Nonionic Surfactants, Ch. 14, (ed. M. J. Schick), Marcel Dekker, New York.

    Google Scholar 

  5. P. H. Elworthy and C. B. Macfarlane (1962) J. Pharm. Pharmac. 14, 100T.

    Google Scholar 

  6. N. Thoai (1977) J. Colloid Interface Sci. 62, 222.

    Google Scholar 

  7. D. Attwood (1969) Kolloid-Z., 232, 788.

    Google Scholar 

  8. M. J. Schick (1962) J. Colloid Sci. 17, 801.

    Google Scholar 

  9. L. Hsiao, H. N. Dunning and P. B. Lorenz (1956) J. Phys. Chem. 60, 657.

    Google Scholar 

  10. E. Ruckenstein and R. Krishnan (1980) J. Colloid Interface Sci. 76, 201.

    Google Scholar 

  11. R. N. Healy and R. L. Reed (1974) Soc. Petrol. Eng. J. 14, 491.

    Google Scholar 

  12. R. N. Healy, R. L. Reed and D. G. Stenmark (1976) Soc. Petrol. Eng. J. 16, 147.

    Google Scholar 

  13. J. L. Cayias, R. S. Schechter and W. H. Wade (1977) J. Colloid Interface Sci. 59, 31.

    Google Scholar 

  14. R. L Cash, J. L. Cayias, G. Fournier, D. Macallister, T. Schanes, R. S. Schechter and W. H. Wade (1977) J. Colloid Interface Sci., 59, 39.

    Google Scholar 

  15. P. M. Dunlap Wilson and C. F. Bradner (1977) J. Colloid Interface Sci. 60, 473.

    Google Scholar 

  16. C. A. Miller, R-N. Hwan, W. J. Benton and T. Fort (1977) J. Colloid Interface Sci. 61, 554.

    Google Scholar 

  17. E. I. Franses, J. E. Pulg, Y. Talmon, W. G. Miller, L. E. Scriven and H. T. Davis(1980), J. Phys. Chem. 84, 1547.

    Google Scholar 

  18. H. Schott (1980) J. Pharm. Sci. 69, 852.

    Google Scholar 

  19. B. A. Pethica (1954) Trans. Faraday Soc. 50, 413.

    Google Scholar 

  20. K. Tajima (1970) Bull. Chem. Soc. Japan 43, 3063.

    Google Scholar 

  21. A. P. Brady (1949) J. Colloid Sci. 4, 417.

    Google Scholar 

  22. E. G. Cockbain and A. I. Mcmullen (1951) Trans. Faraday Soc. 47, 322.

    Google Scholar 

  23. E. G. Cockbain (1954) Trans. Faraday Soc. 50, 874.

    Google Scholar 

  24. D. J. Salley, A. and j. Weith, A. A. Argyle, and J. K. Dixon (1950) Proc. Roy. Soc. A 203, 42.

    Google Scholar 

  25. K. Tajima, M. Muramatsu and T. Sasaki (1970) Bull. Chem. Soc. Japan 43, 1991.

    Google Scholar 

  26. E. Matijevic and B. A. Pethica (1958) Trans. Faraday Soc. 54, 1382, 1390, 1400.

    Google Scholar 

  27. K. Tajima (1971) Bull. Chem. Soc. Japan 44, 1767.

    Google Scholar 

  28. S. Ozeki, M-A. Tsunoda and S. Ikeda (1978) J. Colloid Interface Sci. 64, 28.

    Google Scholar 

  29. S. Ikeda (1977) Bull. Chem. Soc. Japan 50, 1403.

    Google Scholar 

  30. B. Szyszkowski (1908) Z. phys. Chem. 64, 385.

    Google Scholar 

  31. E. H. Lucassen-Reynders and M. van der Tempel (1964) Proc. IVth Int. Cong. Surface Active Substances, Brussels, Vol. II, p. 779.

    Google Scholar 

  32. S. Hachisu (1970) J. Colloid Interface Sci. 33, 445.

    Google Scholar 

  33. J. T. Davies (1951) Proc. Roy. Soc. Ser A A208, 224.

    Google Scholar 

  34. E. H. Lucassen-Reynders (1972) J. Colloid Interface Sci. 41, 156.

    Google Scholar 

  35. M. J. Rosen (1978) Surfactants and Interfacial Phenomena, Ch. 2, Wiley, New York.

    Google Scholar 

  36. F. van Voorst Vader (1960) Trans. Faraday Soc. 56, 1067.

    Google Scholar 

  37. F. M. Menger and S. Wrenn (1974) J. Phys. Chem. 78, 1387.

    Google Scholar 

  38. M. Donbrow (1975) J. Colloid Interfac. Sci. 53, 145.

    Google Scholar 

  39. J. M. Corkill, J. F. Goodman and S. P. Harrold (1964) Trans. Faraday Soc. 60, 202.

    Google Scholar 

  40. R. A. Hudson and B. A. Pethica (1964) Proc. IVth Int. Congr. Surface Active Substances, Brussels, Vol. II, p. 631.

    Google Scholar 

  41. H. Schott (1969) J. Pharm. Sci. 58, 1521.

    Google Scholar 

  42. J. J. Betts and B. A. Pethica (1960) Trans. Faraday Soc. 56, 1515.

    Google Scholar 

  43. J. M. Corkill, J. F. Goodman and J. R. Tate (1966) Trans. Faraday Soc. 62, 979.

    Google Scholar 

  44. H. Kuno and R. Abe (1961) Kolloid-Z. 177, 40.

    Google Scholar 

  45. R. Abe and H. Kuno (1962) Kolloid-Z. 181, 70.

    Google Scholar 

  46. P. H. Elworthy and W. G. Guthrie (1970) J. Pharm. Pharmacol. 22, 114S.

    Google Scholar 

  47. H. Lange (1960) J. Phys. Chem. 64, 538.

    Google Scholar 

  48. K. G. Mathai and R. H. Ottewill (1962) Kolloid-Z. 185, 55.

    Google Scholar 

  49. K. G. Mathai and R. H. Ottewill (1966) Trans. Faraday Soc. 62, 750, 759.

    Google Scholar 

  50. F. G. Greenwood, G. D. Parfitt, N. H. Picton and D. G. Wharton (1968) in Adsorption from Aqueous Solution (eds. W. J. Weber and E. Matijevic) American Chemical Society, Washington DC, p. 135.

    Google Scholar 

  51. P. Connor and R. H. Ottewill (1971) J. Colloid Interface Sci. 37, 642.

    Google Scholar 

  52. P. Mukerjee and A. Anavil (1975) in Adsorption at Interfaces, ACS Symposium Series No. 8. American Chemical Society, Washington, p. 107.

    Google Scholar 

  53. B. Tamamushi and K. Tamaki (1957) Proc. Ilnd Intern. Cong. Surface Activity London, Vol. III. Butterworths, London, p. 449.

    Google Scholar 

  54. T. Wakamatsu and D. W. Fuerstenau (1968) in Adsorption from Aqueous Solution, (eds. W. J. Weber and E. Matijevic) American Chem. Society, Washington DC, p. 161.

    Google Scholar 

  55. S. G. Dick, D. W. Fuerstenau and T. W. Healy (1971) J. Colloid Interface Sci. 37, 595.

    Google Scholar 

  56. D. W. Fuerstenau (1956) J. Phys. Chem. 60, 981.

    Google Scholar 

  57. P. Somasundaran, T. W. Healy and D. W. Fuerstenau (1964) J. Phys. Chem. 68, 3562.

    Google Scholar 

  58. P. Somasundaran and D. W. Fuerstenau (1966) J. Phys. Chem. 70, 90.

    Google Scholar 

  59. D. J. Wilson and R. Moffatt Kennedy (1979) Sepn. Sci. Techn. 14, 319.

    Google Scholar 

  60. M. L. Corrin, E. L. Lind, A. Roginsky, and W. D. Harkins (1949) J. Colloid Sci. 4, 485.

    Google Scholar 

  61. R. D. Vold and N. H. Sivaramakrishnan (1958) J. Phys. Chem. 62, 984.

    Google Scholar 

  62. R. D. Vold and A. K. Phansalkar (1955) Ree. trav. chim. 74, 41.

    Google Scholar 

  63. A. Fava and H. Eyring (1956) J. Phys. Chem. 60, 890.

    Google Scholar 

  64. A. T. Florence and D. Attwood (1981) Physicochemical Principles of Pharmacy, ch. 9, Macmillan, London.

    Google Scholar 

  65. H. Nogami, T. Nagai and S. Wada (1970) Chem. Pharm. Bull. 18, 342, 348.

    Google Scholar 

  66. H. Nogami, T. Nagai and H. Uchida (1969) Chem. Pharm. Bull. 17, 176.

    Google Scholar 

  67. H. Nogami, T. Nagai and N. Nambu (1970) Chem. Pharm. Bull. 18, 1643.

    Google Scholar 

  68. H. nogami, S. Sakurai and T. Nagai (1975) Chem. Pharm. Bull. 23, 1404.

    Google Scholar 

  69. S. El-Masry and S. A. H. Khalil (1974) J. Pharm. Pharmacol. 26, 243.

    Google Scholar 

  70. S. A. H. Khalil and M. Iwuagwa (1978) J. Pharm. Sci. 67, 287.

    Google Scholar 

  71. B. Tamamushi and K. Tamaki (1959) Trans. Faraday Soc. 55, 1007.

    Google Scholar 

  72. G. R. F. Rose, A. S. Weatherburn and C. H. Bayley (1951) Textile Research J. 22, 797.

    Google Scholar 

  73. H. Rupprecht (1978) Progr. Colloid and Polymer Sci. 65, 29.

    Google Scholar 

  74. G. Bauer and E. Ullmann (1973) Arch. Pharmazie 306, 86.

    Google Scholar 

  75. K. Kakemi, H. Sezaki, E. Arakawa, K. Kimura and K. Ikeda (1971) Chem. Pharm. Bull. 19, 2523.

    Google Scholar 

  76. N. E. Richardson and B. J. Meakin (1974) J. Pharm. Pharmacol. 26, 166.

    Google Scholar 

  77. H. van Olphen (1976) Progr. Colloid and Polymer Sci. 61, 46.

    Google Scholar 

  78. J. E. Browne, J. R. Feldkamp, J. L. White and S. L. Hem (1980) J. Pharm. Sci. 69, 816.

    Google Scholar 

  79. J. C. Arnell and W. M. Barss. (1948) Can. J. Research 26A, 236.

    Google Scholar 

  80. P. H. Emmett (1948) Chem. Rev. 43, 69.

    Google Scholar 

  81. W. F. Wolff (1958) J. Phys. Chem. 62, 829.

    Google Scholar 

  82. J. S. Mattson and H. B. Mark (1969) J. Colloid Interface Sci. 31, 131.

    Google Scholar 

  83. A. J. Kapadia, W. L. Guess and J. Autian (1964) J. Pharm. Sci. 53, 28.

    Google Scholar 

  84. A W. Neumann (1974) Adv. Colloid Interface Sci. 4, 105.

    Google Scholar 

  85. B. A Pethica (1977) J. Colloid Interface Sci. 62, 568.

    Google Scholar 

  86. R. E. Johnson and R. H. Dettre (1969) Surface and Colloid Science, (ed. E. Matijevic) Vol. 2, Wiley-Interscience, p. 85.

    Google Scholar 

  87. E. W. Washburn (1921) Phys. Rev. 17, 273.

    Google Scholar 

  88. F. E. Bartell and H. J. Osterhof (1927) Ind. Eng. Chem. 19, 1277.

    Google Scholar 

  89. G. Zografi and S. Tam (1976) J. Pharm. Sci. 65, 1145.

    Google Scholar 

  90. P. M. Heertjes and N. W. F. Kossen (1965) Chem. Eng. Sci. 20, 593.

    Google Scholar 

  91. C. F. Lerk, A. J. M. Schoonen and J. T. Fell (1976) J. Pharm. Sci. 65, 843.

    Google Scholar 

  92. C. F. Lerk, M. Lagas, J. P. Boelstra and P. Broersma (1977) J. Pharm. Sci. 66, 1480.

    Google Scholar 

  93. M. L. A. Studebaker and C W. Snow (1955) J. Phys. Chem. 59, 973.

    Google Scholar 

  94. D. T. Hansford, D. J. W. Grant and J. M. Newton (1980) Powder Technol. 26, 119.

    Google Scholar 

  95. G. D. Parfitt (1973) Dispersion of Powders in Liquids, 2nd edn., Applied Science, London, Ch. 1.

    Google Scholar 

  96. W. A. Zisman (1964) Adv. Chem. 43, 1.

    Google Scholar 

  97. H. W. Fox and W. A. Zisman (1952) J. Colloid. Sci. 7, 428.

    Google Scholar 

  98. J. T. Fell and E. Efentakis (1978) J. Pharm. Pharmacol. 30, 538.

    Google Scholar 

  99. E. G. Shafrin and W. A. Zisman (1960) J. Phys. Chem. 64, 519.

    Google Scholar 

  100. S. W. Harder, D. A. Zuck and J. A. Wood (1970) J. Pharm. Sci. 59, 1787.

    Google Scholar 

  101. G. D. Parfitt and D. G. Wharton (1972) J. Colloid Interface Sci. 38, 431.

    Google Scholar 

  102. G A. H. Elton (1957) Proc. Ilnd Int. Cong. Surface Activity, London, vol. III, p. 161.

    Google Scholar 

  103. D. P. Benton and B. D. Sparks (1966) Trans. Faraday Soc. 62, 3244.

    Google Scholar 

  104. J. Powney and L. J. Wood (1941) Trans. Faraday Soc. 37, 220.

    Google Scholar 

  105. D. W Fuerstenau (1957) Trans. A.I.M.E. 208, 1365.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 1983 D. Attwood and A. T. Florence

About this chapter

Cite this chapter

Attwood, D., Florence, A.T. (1983). Surface activity. In: Surfactant Systems. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-5775-6_1

Download citation

  • DOI: https://doi.org/10.1007/978-94-009-5775-6_1

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-009-5777-0

  • Online ISBN: 978-94-009-5775-6

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics