Abstract
A surface-active agent is, as the name implies, a compound which will adsorb at an air-water or oil-water interface and at the surface of solids. The structural features of these molecules which are responsible for surface activity are examined in this chapter and some of the factors which influence the extent of adsorption are considered. A study of the adsorption process is of fundamental importance in an understanding of the properties of surface-active compounds since, as we will discuss in later chapters, it is the change in interfacial free energy and surface charge resulting from adsorption which leads to the ability of these compounds to act as emulsifying and suspending agents. A survey of the wide variety of surfactants which are used in pharmaceutical systems is included in the chapter, together with a brief indication of the many and diverse uses of this versatile group of compounds.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
G. Némethy and H. S. Sheraga (1962) J. Chem. Phys. 36, 3382.
F. Franks, J. Ravenhill, P. A. Egelstaff and D. I Page (1970) Proc. Roy. Soc.(London) A 319, 189.
I. Danielsson, B. Lindman and L. Odberg (1969) Suomen Kemistilehti 42, 209.
H. Lange(1966) in Nonionic Surfactants, Ch. 14, (ed. M. J. Schick), Marcel Dekker, New York.
P. H. Elworthy and C. B. Macfarlane (1962) J. Pharm. Pharmac. 14, 100T.
N. Thoai (1977) J. Colloid Interface Sci. 62, 222.
D. Attwood (1969) Kolloid-Z., 232, 788.
M. J. Schick (1962) J. Colloid Sci. 17, 801.
L. Hsiao, H. N. Dunning and P. B. Lorenz (1956) J. Phys. Chem. 60, 657.
E. Ruckenstein and R. Krishnan (1980) J. Colloid Interface Sci. 76, 201.
R. N. Healy and R. L. Reed (1974) Soc. Petrol. Eng. J. 14, 491.
R. N. Healy, R. L. Reed and D. G. Stenmark (1976) Soc. Petrol. Eng. J. 16, 147.
J. L. Cayias, R. S. Schechter and W. H. Wade (1977) J. Colloid Interface Sci. 59, 31.
R. L Cash, J. L. Cayias, G. Fournier, D. Macallister, T. Schanes, R. S. Schechter and W. H. Wade (1977) J. Colloid Interface Sci., 59, 39.
P. M. Dunlap Wilson and C. F. Bradner (1977) J. Colloid Interface Sci. 60, 473.
C. A. Miller, R-N. Hwan, W. J. Benton and T. Fort (1977) J. Colloid Interface Sci. 61, 554.
E. I. Franses, J. E. Pulg, Y. Talmon, W. G. Miller, L. E. Scriven and H. T. Davis(1980), J. Phys. Chem. 84, 1547.
H. Schott (1980) J. Pharm. Sci. 69, 852.
B. A. Pethica (1954) Trans. Faraday Soc. 50, 413.
K. Tajima (1970) Bull. Chem. Soc. Japan 43, 3063.
A. P. Brady (1949) J. Colloid Sci. 4, 417.
E. G. Cockbain and A. I. Mcmullen (1951) Trans. Faraday Soc. 47, 322.
E. G. Cockbain (1954) Trans. Faraday Soc. 50, 874.
D. J. Salley, A. and j. Weith, A. A. Argyle, and J. K. Dixon (1950) Proc. Roy. Soc. A 203, 42.
K. Tajima, M. Muramatsu and T. Sasaki (1970) Bull. Chem. Soc. Japan 43, 1991.
E. Matijevic and B. A. Pethica (1958) Trans. Faraday Soc. 54, 1382, 1390, 1400.
K. Tajima (1971) Bull. Chem. Soc. Japan 44, 1767.
S. Ozeki, M-A. Tsunoda and S. Ikeda (1978) J. Colloid Interface Sci. 64, 28.
S. Ikeda (1977) Bull. Chem. Soc. Japan 50, 1403.
B. Szyszkowski (1908) Z. phys. Chem. 64, 385.
E. H. Lucassen-Reynders and M. van der Tempel (1964) Proc. IVth Int. Cong. Surface Active Substances, Brussels, Vol. II, p. 779.
S. Hachisu (1970) J. Colloid Interface Sci. 33, 445.
J. T. Davies (1951) Proc. Roy. Soc. Ser A A208, 224.
E. H. Lucassen-Reynders (1972) J. Colloid Interface Sci. 41, 156.
M. J. Rosen (1978) Surfactants and Interfacial Phenomena, Ch. 2, Wiley, New York.
F. van Voorst Vader (1960) Trans. Faraday Soc. 56, 1067.
F. M. Menger and S. Wrenn (1974) J. Phys. Chem. 78, 1387.
M. Donbrow (1975) J. Colloid Interfac. Sci. 53, 145.
J. M. Corkill, J. F. Goodman and S. P. Harrold (1964) Trans. Faraday Soc. 60, 202.
R. A. Hudson and B. A. Pethica (1964) Proc. IVth Int. Congr. Surface Active Substances, Brussels, Vol. II, p. 631.
H. Schott (1969) J. Pharm. Sci. 58, 1521.
J. J. Betts and B. A. Pethica (1960) Trans. Faraday Soc. 56, 1515.
J. M. Corkill, J. F. Goodman and J. R. Tate (1966) Trans. Faraday Soc. 62, 979.
H. Kuno and R. Abe (1961) Kolloid-Z. 177, 40.
R. Abe and H. Kuno (1962) Kolloid-Z. 181, 70.
P. H. Elworthy and W. G. Guthrie (1970) J. Pharm. Pharmacol. 22, 114S.
H. Lange (1960) J. Phys. Chem. 64, 538.
K. G. Mathai and R. H. Ottewill (1962) Kolloid-Z. 185, 55.
K. G. Mathai and R. H. Ottewill (1966) Trans. Faraday Soc. 62, 750, 759.
F. G. Greenwood, G. D. Parfitt, N. H. Picton and D. G. Wharton (1968) in Adsorption from Aqueous Solution (eds. W. J. Weber and E. Matijevic) American Chemical Society, Washington DC, p. 135.
P. Connor and R. H. Ottewill (1971) J. Colloid Interface Sci. 37, 642.
P. Mukerjee and A. Anavil (1975) in Adsorption at Interfaces, ACS Symposium Series No. 8. American Chemical Society, Washington, p. 107.
B. Tamamushi and K. Tamaki (1957) Proc. Ilnd Intern. Cong. Surface Activity London, Vol. III. Butterworths, London, p. 449.
T. Wakamatsu and D. W. Fuerstenau (1968) in Adsorption from Aqueous Solution, (eds. W. J. Weber and E. Matijevic) American Chem. Society, Washington DC, p. 161.
S. G. Dick, D. W. Fuerstenau and T. W. Healy (1971) J. Colloid Interface Sci. 37, 595.
D. W. Fuerstenau (1956) J. Phys. Chem. 60, 981.
P. Somasundaran, T. W. Healy and D. W. Fuerstenau (1964) J. Phys. Chem. 68, 3562.
P. Somasundaran and D. W. Fuerstenau (1966) J. Phys. Chem. 70, 90.
D. J. Wilson and R. Moffatt Kennedy (1979) Sepn. Sci. Techn. 14, 319.
M. L. Corrin, E. L. Lind, A. Roginsky, and W. D. Harkins (1949) J. Colloid Sci. 4, 485.
R. D. Vold and N. H. Sivaramakrishnan (1958) J. Phys. Chem. 62, 984.
R. D. Vold and A. K. Phansalkar (1955) Ree. trav. chim. 74, 41.
A. Fava and H. Eyring (1956) J. Phys. Chem. 60, 890.
A. T. Florence and D. Attwood (1981) Physicochemical Principles of Pharmacy, ch. 9, Macmillan, London.
H. Nogami, T. Nagai and S. Wada (1970) Chem. Pharm. Bull. 18, 342, 348.
H. Nogami, T. Nagai and H. Uchida (1969) Chem. Pharm. Bull. 17, 176.
H. Nogami, T. Nagai and N. Nambu (1970) Chem. Pharm. Bull. 18, 1643.
H. nogami, S. Sakurai and T. Nagai (1975) Chem. Pharm. Bull. 23, 1404.
S. El-Masry and S. A. H. Khalil (1974) J. Pharm. Pharmacol. 26, 243.
S. A. H. Khalil and M. Iwuagwa (1978) J. Pharm. Sci. 67, 287.
B. Tamamushi and K. Tamaki (1959) Trans. Faraday Soc. 55, 1007.
G. R. F. Rose, A. S. Weatherburn and C. H. Bayley (1951) Textile Research J. 22, 797.
H. Rupprecht (1978) Progr. Colloid and Polymer Sci. 65, 29.
G. Bauer and E. Ullmann (1973) Arch. Pharmazie 306, 86.
K. Kakemi, H. Sezaki, E. Arakawa, K. Kimura and K. Ikeda (1971) Chem. Pharm. Bull. 19, 2523.
N. E. Richardson and B. J. Meakin (1974) J. Pharm. Pharmacol. 26, 166.
H. van Olphen (1976) Progr. Colloid and Polymer Sci. 61, 46.
J. E. Browne, J. R. Feldkamp, J. L. White and S. L. Hem (1980) J. Pharm. Sci. 69, 816.
J. C. Arnell and W. M. Barss. (1948) Can. J. Research 26A, 236.
P. H. Emmett (1948) Chem. Rev. 43, 69.
W. F. Wolff (1958) J. Phys. Chem. 62, 829.
J. S. Mattson and H. B. Mark (1969) J. Colloid Interface Sci. 31, 131.
A. J. Kapadia, W. L. Guess and J. Autian (1964) J. Pharm. Sci. 53, 28.
A W. Neumann (1974) Adv. Colloid Interface Sci. 4, 105.
B. A Pethica (1977) J. Colloid Interface Sci. 62, 568.
R. E. Johnson and R. H. Dettre (1969) Surface and Colloid Science, (ed. E. Matijevic) Vol. 2, Wiley-Interscience, p. 85.
E. W. Washburn (1921) Phys. Rev. 17, 273.
F. E. Bartell and H. J. Osterhof (1927) Ind. Eng. Chem. 19, 1277.
G. Zografi and S. Tam (1976) J. Pharm. Sci. 65, 1145.
P. M. Heertjes and N. W. F. Kossen (1965) Chem. Eng. Sci. 20, 593.
C. F. Lerk, A. J. M. Schoonen and J. T. Fell (1976) J. Pharm. Sci. 65, 843.
C. F. Lerk, M. Lagas, J. P. Boelstra and P. Broersma (1977) J. Pharm. Sci. 66, 1480.
M. L. A. Studebaker and C W. Snow (1955) J. Phys. Chem. 59, 973.
D. T. Hansford, D. J. W. Grant and J. M. Newton (1980) Powder Technol. 26, 119.
G. D. Parfitt (1973) Dispersion of Powders in Liquids, 2nd edn., Applied Science, London, Ch. 1.
W. A. Zisman (1964) Adv. Chem. 43, 1.
H. W. Fox and W. A. Zisman (1952) J. Colloid. Sci. 7, 428.
J. T. Fell and E. Efentakis (1978) J. Pharm. Pharmacol. 30, 538.
E. G. Shafrin and W. A. Zisman (1960) J. Phys. Chem. 64, 519.
S. W. Harder, D. A. Zuck and J. A. Wood (1970) J. Pharm. Sci. 59, 1787.
G. D. Parfitt and D. G. Wharton (1972) J. Colloid Interface Sci. 38, 431.
G A. H. Elton (1957) Proc. Ilnd Int. Cong. Surface Activity, London, vol. III, p. 161.
D. P. Benton and B. D. Sparks (1966) Trans. Faraday Soc. 62, 3244.
J. Powney and L. J. Wood (1941) Trans. Faraday Soc. 37, 220.
D. W Fuerstenau (1957) Trans. A.I.M.E. 208, 1365.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 1983 D. Attwood and A. T. Florence
About this chapter
Cite this chapter
Attwood, D., Florence, A.T. (1983). Surface activity. In: Surfactant Systems. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-5775-6_1
Download citation
DOI: https://doi.org/10.1007/978-94-009-5775-6_1
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-009-5777-0
Online ISBN: 978-94-009-5775-6
eBook Packages: Springer Book Archive