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Erschienen in: Journal of Materials Science 5/2019

19.11.2018 | Materials for life sciences

Characterization and antimicrobial activity of a 2-O-methyl-β-cyclodextrin inclusion complex containing hexahydro-β-acids

verfasst von: Na Lu, Haining Xu, Yumei Liu

Erschienen in: Journal of Materials Science | Ausgabe 5/2019

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Abstract

An inclusion complex of hexahydro-β-acids (HBA) and 2-O-methyl-β-cyclodextrin (M-β-CD) was prepared using the grinding method to improve the water solubility of HBA. Complex formation was assessed using ultraviolet and visible light (UV–Vis) spectroscopy, Fourier transform infrared spectroscopy (FT-IR), X-ray diffractometry (XRD), nuclear magnetic resonance (1HNMR), and scanning electron microscopy (SEM). Results showed that the HBA molecule resided within the M-β-CD cavity. The water solubility test indicated that the effect of the M-β-CD encapsulation extended beyond increasing the solubility of HBA. Furthermore, the antibacterial activity of the HBA/M-β-CD inclusion complex, pure HBA, and M-β-CD against different food-related microorganisms was determined by an agar diffusion assay. Particularly, the HBA/M-β-CD inclusion complex exhibited better antibacterial activity against Listeria monocytogenes. These results suggest that incorporation of the HBA/M-β-CD inclusion complex in food might effectively inhibit L. monocytogenes growth.

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Metadaten
Titel
Characterization and antimicrobial activity of a 2-O-methyl-β-cyclodextrin inclusion complex containing hexahydro-β-acids
verfasst von
Na Lu
Haining Xu
Yumei Liu
Publikationsdatum
19.11.2018
Verlag
Springer US
Erschienen in
Journal of Materials Science / Ausgabe 5/2019
Print ISSN: 0022-2461
Elektronische ISSN: 1573-4803
DOI
https://doi.org/10.1007/s10853-018-3148-9

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