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Erschienen in:
Clinical and Biomedical Engineering in the Human Nose Kapitel lesen Erstes Kapitel lesen

2021 | OriginalPaper | Buchkapitel

8. Clinical Implications of Nasal Airflow Simulations

verfasst von : Dennis Onyeka Frank-Ito, Guilherme Garcia

Erschienen in: Clinical and Biomedical Engineering in the Human Nose

Verlag: Springer Singapore

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Abstract

This chapter provides an up-to-date literature review on the relevance of CFD modeling results in clinical settings and the efforts made in the field to establish normative ranges for some CFD-derived variables. We discuss the significance of CFD-derived variables such as unilateral nasal airflow partitioning, nasal airway resistance, heat flux and wall shear stress on nasal function or symptomatology, and the strong associations established with these variables. Two important issues are discussed: (i) a need to establish meaningful representation involving combinations of different computed variables in order to accurately capture the full dynamical nature of patient-reported symptomatology; (ii) a need to develop a robust database of normative values for CFD-derived variables since typical healthy human sinonasal airway anatomies are characterized by substantial intersubject variability that confound concise description of normal airflow profile.

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Vorheriges Kapitel Fundamentals of Fluid Dynamics
Nächstes Kapitel Clinical CFD Applications 1
Fußnoten
1
This relation is obtained using the definitions of airflow partitioning, nasal resistance, and the fact that the pressure drop is the same in the left and right cavities.
 
Literatur
1.
L. Akmenkalne, M. Prill, K. Vogt, Nasal valve elastography: quantitative determination of the mobility of the nasal valve. Rhinol. Online 2, 81–86 (2019)CrossRef
2.
J. Alberty, W. Stoll, C. Rudack, The effect of endogenous nitric oxide on mechanical ciliostimulation of human nasal mucosa. Clin. Exp. Allergy 36(10), 1254–1259 (2006)CrossRef
3.
R.F. Andre, H.D. Vuyk, A. Ahmed, K. Graamans, G.J. Nolst Trenite, Correlation between subjective and objective evaluation of the nasal airway. a systematic review of the highest level of evidence. Clin .Otolaryngol. 34(6), 518–25 (2009)
4.
W.T. Anselmo-Lima, V.J. Lund, The effects of endoscopic sinus surgery on the nasal cycle as assessed by acoustic rhinometry. Am. J. Rhinol. 15(3), 165–8 (2001)CrossRef
5.
M. Antosova, D. Mokra, I. Tonhajzerova, P. Mikolka, P. Kosutova, M. Mestanik, L. Pepucha, J. Plevkova, T. Buday, V. Calkovsky, Nasal nitric oxide in healthy adults-reference values and affecting factors. Physiolog. Res. 66, S247 (2017)CrossRef
6.
F.D. Babatola, Nasal resistance values in the adult negroid nigerian. Rhinology 28(4), 269–73 (1990)
7.
R.S. Bailey, K.P. Casey, S.S. Pawar, G.J. Garcia, Correlation of nasal mucosal temperature with subjective nasal patency in healthy individuals. JAMA Facial Plast. Surg. 19(1), 46–52 (2017)CrossRef
8.
E. Baraldi, M. Pasquale, A. Cangiotti, S. Zanconato, F. Zacchello, Nasal nitric oxide is low early in life: case study of two infants with primary ciliary dyskinesia. Eur. Respir. J. 24(5), 881–883 (2004)CrossRef
9.
G. Berger, I. Hammel, R. Berger, S. Avraham, D. Ophir, Histopathology of the inferior turbinate with compensatory hypertrophy in patients with deviated nasal septum. The laryngoscope 110(12), 2100–2105 (2000)CrossRef
10.
E.R. Berkinshaw, P.M. Spalding, P.S. Vig, The effect of methodology on the determination of nasal resistance (Am. J. Orthod. Dentofac, Orthop, 1987)CrossRef
11.
C. Bermüller, H. Kirsche, G. Rettinger, H. Riechelmann, Diagnostic accuracy of peak nasal inspiratory flow and rhinomanometry in functional rhinosurgery. The Laryngoscope 118(4), 605–610 (2008)CrossRef
12.
S. Blaney, Why paranasal sinuses? J. Laryngol. Otol. 104(9), 690–693 (1990)CrossRef
13.
P.L. Blanton, N.L. Biggs, Eighteen hundred years of controversy: the paranasal sinuses. Am. J. Anat. 124(2), 135–147 (1969)CrossRef
14.
A.A. Borojeni, G.J. Garcia, M.G. Moghaddam, D.O. Frank-Ito, J.S. Kimbell, P.W. Laud, L.J. Koenig, J.S. Rhee, Normative ranges of nasal airflow variables in healthy adults. International Journal of Computer Assisted Radiology and Surgery 1–12, (2019)
15.
A. Burrow, R. Eccles, A.S. Jones, The effects of camphor, eucalyptus and menthol vapour on nasal resistance to airflow and nasal sensation. Acta Otolaryngol. 96(1–2), 157–61 (1983)CrossRef
16.
O. Cakmak, E. Tarhan, M. Coskun, M. Cankurtaran, H. Celik, Acoustic rhinometry: accuracy and ability to detect changes in passage area at different locations in the nasal cavity. Ann. Otol. Rhinol. Laryngol. 114(12), 949–57 (2005)CrossRef
17.
K.H. Calhoun, W. House, J.A. Hokanson, F.B. Quinn, Normal nasal airway-resistance in noses of different sizes and shapes. Otolaryngol. Head Neck Surg. 103(4), 605–609 (1990)CrossRef
18.
K.P. Casey, A.A. Borojeni, L.J. Koenig, J.S. Rhee, G.J. Garcia, Correlation between subjective nasal patency and intranasal airflow distribution. Otolaryngol. Head Neck Surg. (United States) (2017)
19.
R.K. Chandra, M.O. Patadia, J. Raviv, Diagnosis of nasal airway obstruction. Otolaryngol. Clin. N. Am. 42(2), 207–225 (2009)CrossRef
20.
G.B. Cherobin, R.L. Voegels, E. Gebrim, G.J.M. Garcia, Sensitivity of nasal airflow variables computed via computational fluid dynamics to the computed tomography segmentation threshold. PLoS One 13(11), e0207178 (2018)CrossRef
21.
S. Chung, H. Dhong, D. Na, Mucus circulation between accessory ostium and natural ostium of maxillary sinus. J. Laryngol. Otol. 113(9), 865–867 (1999)CrossRef
22.
S.-K. Chung, D.Y. Cho, H.J. Dhong, Computed tomogram findings of mucous recirculation between the natural and accessory ostia of the maxillary sinus. Am. J. Rhinol. 16(5), 265–268 (2002)CrossRef
23.
S.E. Churchill, L.L. Shackelford, J.N. Georgi, M.T. Black, Morphological variation and airflow dynamics in the human nose. Am. J. Hum. Biol.: Off. J. Hum. Biol. Assoc. 16(6), 625–638 (2004)
24.
P.A. Clement, F. Gordts, Standardisation Committee on Objective Assessment of the Nasal Airway, I. R. S., Ers. Consensus report on acoustic rhinometry and rhinomanometry. Rhinology 43(3), 169–79 (2005)
25.
P. Clements, F. Gortds, Standardisation committee on objective assessment of the nasal airway, irs, and ers consensus report on acoustic rhinometry and rhinomanometry. Rhynology 43(3), 169–179 (2005)
26.
P. Cole, Physiology of the nose and paranasal sinuses. Clin. Rev. Allergy Immunol. 16(1–2), 25–54 (1998)CrossRef
27.
R. Corbelli, J. Hammer, Measurement of nasal nitric oxide. Paediatr. Respir. Rev. 8(3), 269–272 (2007)CrossRef
28.
J.P. Corey, Acoustic rhinometry: should we be using it? Curr. Opin. Otolaryngol. Head Neck Surg. 14(1), 29–34 (2006)CrossRef
29.
B.A. Craven, T. Neuberger, E.G. Paterson, A.G. Webb, E.M. Josephson, E.E. Morrison, G.S. Settles, Reconstruction and morphometric analysis of the nasal airway of the dog (canis familiaris) and implications regarding olfactory airflow. Anat. Rec. (Hoboken) 290(11), 1325–40 (2007)CrossRef
30.
E. Crognier, Climate and anthropometric variations in Europe and the mediterranean area. Ann. Hum. Biol. 8(2), 99–107 (1981)CrossRef
31.
R.K. Daniel, Hispanic rhinoplasty in the united states, with emphasis on the Mexican American nose. Plast. Reconstr. Surg. 112(1), 244–56; discussion 257–8 (2003)
32.
A. Davies, A re-survey of the morphology of the nose in relation to climate. J. R. Anthropol. Inst. G. B. Irel. 62, 337–359 (1932)
33.
W.B. Davis, Lv. anatomy of the nasal accessory sinuses in infancy and childhood. Ann. Otol. Rhinol. Laryngol. 27(3), 940–967 (1918)
34.
A. Dayal, J.S. Rhee, G.J. Garcia, Impact of middle versus inferior total turbinectomy on nasal aerodynamics. Otolaryngol. Head Neck Surg. 155(3), 518–25 (2016)CrossRef
35.
H.P.L. De Yun Wang, B.R. Gordon, Impacts of fluid dynamics simulation in study of nasal airflow physiology and pathophysiology in realistic human three-dimensional nose models. Clin. Exp. Otorhinolaryngol. 5(4), 181 (2012)
36.
N.M. Doddi, R. Eccles, The relationship between nasal index and nasal airway resistance, and response to a topical decongestant. Rhinology 49(5), 583–6 (2011)
37.
J. Dong, J. Ma, Y. Shang, K. Inthavong, D. Qiu, J. Tu, D. Frank-Ito, Detailed nanoparticle exposure analysis among human nasal cavities with distinct vestibule phenotypes. J. Aerosol Sci. 121, 54–65 (2018)CrossRef
38.
D.J. Doorly, D.J. Taylor, R.C. Schroter, Mechanics of airflow in the human nasal airways. Respir. Physiol. Neurobiol. 163(1–3), 100–10 (2008)CrossRef
39.
J. Earwaker, Anatomic variants in sinonasal ct. Radiographics 13(2), 381–415 (1993)CrossRef
40.
R. Eccles, A role for the nasal cycle in respiratory defence. Eur. Respir. J. 9(2), 371–376 (1996)CrossRef
41.
R. Eccles, Nasal airflow in health and disease. Acta Otolaryngol. 120(5), 580–595 (2000)CrossRef
42.
R. Eccles, D.H. Griffiths, C.G. Newton, N.S. Tolley, The effects of menthol isomers on nasal sensation of airflow. Clin. Otolaryngol. Allied Sci. 13(1), 25–9 (1988)CrossRef
43.
R. Eccles, A.S. Jones, The effect of menthol on nasal resistance to air flow. J. Laryngol. Otol. 97(8), 705–9 (1983)CrossRef
44.
T.P. Eiting, J.B. Perot, E.R. Dumont, How much does nasal cavity morphology matter? patterns and rates of olfactory airflow in phyllostomid bats. Proc. Biol. Sci. 282(1800), 20142161 (2015)
45.
T.P. Eiting, T.D. Smith, J.B. Perot, E.R. Dumont, The role of the olfactory recess in olfactory airflow. J. Exp. Biol. 217(Pt 10), 1799–803 (2014)CrossRef
46.
D. Elad, R. Liebenthal, B.L. Wenig, S. Einav, Analysis of air flow patterns in the human nose. Med. Biol. Eng. Comput. 31(6), 585–92 (1993)CrossRef
47.
E.W. Fisher, D.P. Morris, J.M. Biemans, C.R. Palmer, V.J. Lund, Practical aspects of acoustic rhinometry: problems and solutions. Rhinology 33(4), 219–23 (1995)
48.
P. Flanagan, R. Eccles, Spontaneous changes of unilateral nasal airflow in man. a re-examination of the ‘nasal cycle’. Acta Otolaryngol. 117(4), 590–595 (1997)
49.
50.
A.M. Gambaruto, D.J. Taylor, D.J. Doorly, Decomposition and description of the nasal cavity form. Ann. Biomed. Eng. 40(5), 1142–59 (2012)CrossRef
51.
G.J. Garcia, E.W. Tewksbury, B.A. Wong, J.S. Kimbell, Interindividual variability in nasal filtration as a function of nasal cavity geometry. J. Aerosol. Med. Pulm. Drug Deliv. 22(2), 139–55 (2009)CrossRef
52.
G.J.M. Garcia, B.M. Hariri, R.G. Patel, J.S. Rhee, The relationship between nasal resistance to airflow and the airspace minimal cross-sectional area. J. Biomech. 49(9), 1670–1678 (2016)CrossRef
53.
G. Garcia, G. Mitchell, B. N. T. D. W. J. K. J. Visualization of nasal airflow patterns in a patient affected with atrophic rhinitis using particle image velocimetry. J. Phys.: Conf. Ser. 85 (2007)
54.
Q.J. Ge, K. Inthavong, J.Y. Tu, Local deposition fractions of ultrafine particles in a human nasal-sinus cavity cfd model. Inhal. Toxicol. 24(8), 492–505 (2012)CrossRef
55.
A.N. Gilbert, Reciprocity versus rhythmicity in spontaneous alternations of nasal airflow. Chronobiol. Int. 6(3), 251–257 (1989)CrossRef
56.
S. Granqvist, J. Sundberg, J.O. Lundberg, E. Weitzberg, Paranasal sinus ventilation by humming. J. Acoust. Soc. Am. 119(5), 2611–2617 (2006)CrossRef
57.
L.F. Grymer, P. Illum, O. Hilberg, Septoplasty and compensatory inferior turbinate hypertrophy: a randomized study evaluated by acoustic rhinometry. J. Laryngol. Otol. 107(5), 413–7 (1993)CrossRef
58.
R.A. Guilmette, Y.S. Cheng, W.C. Griffith, Characterising the variability in adult human nasal airway dimensions. Ann. Occup. Hyg. 41(1), 491–496 (1997)
59.
A. Gungor, R. Moinuddin, R.H. Nelson, J.P. Corey, Detection of the nasal cycle with acoustic rhinometry: techniques and applications. Otolaryngol. Head Neck Surg. 120(2), 238–47 (1999)CrossRef
60.
I. Hahn, P. Scherer, M. Mozell, Velocity profiles measured for air-flow through a large-scale model of the human nasal cavity. J. Appl. Physiol. 75(5), 2273–2287 (1993)CrossRef
61.
J.S. Haight, P. Djupesland, W. Qjan, J. Chatkin, H. Furlott, J. Irish, I. Witterick, P. McClean, R. Fenton, V. Hoffstein, Does nasal nitric oxide come from the sinuses? J. Otolaryngol. 28(4), 197–204 (1999)
62.
M. Hasegawa, E. Kern, Variations in nasal resistance in man: a rhinomanometric study of the nasal cycle in 50 human subjects. Rhinology 16(1), 19–29 (1978)
63.
M. Hasegawa, E.B. Kern, Variations in nasal resistance in man: a rhinomanometric study of the nasal cycle in 50 human subjects. Rhinology 16(1), 19–29 (1978)
64.
K. Hemtiwakorn, V. Mahasitthiwat, S. Tungjitkusolmun, K. Hamamoto, C. Pintavirooj, Patient-specific aided surgery approach of deviated nasal septum using computational fluid dynamics. IEEJ Trans. Electr. Electron. Eng. 10(3), 274–286 (2015)CrossRef
65.
J. Hiernaux, A. Froment, Correlations between anthropo-biological and climatic variables in sub-saharan Africa - revised estimates. Hum. Biol. 48(4), 757–767 (1976)
66.
O. Hilberg, A.C. Jackson, D.L. Swift, O.F. Pedersen, Acoustic rhinometry: evaluation of nasal cavity geometry by acoustic reflection. J. Appl. Physiol. (1985) 66(1), 295–303 (1989)
67.
W.E. Holden, J.P. Wilkins, M. Harris, H.A. Milczuk, G.D. Giraud, Temperature conditioning of nasal air: effects of vasoactive agents and involvement of nitric oxide. J. Appl. Physiol. (1985) 87(4), 1260–5 (1999)
68.
C. Hood, R. Schroter, D. Doorly, E. Blenke, N. Tolley, Computational modeling of flow and gas exchange in models of the human maxillary sinus. J. Appl. Physiol. 107, 1195–1203 (2009)CrossRef
69.
K. Inthavong, J. Ma, Y. Shang, J. Dong, A.S. Chetty, J. Tu, D. Frank-Ito, Geometry and airflow dynamics analysis in the nasal cavity during inhalation. Clinical Biomechanics (2017)
70.
K. Inthavong, J. Wen, J.Y. Tu, Z.F. Tian, From ct scans to cfd modelling - fluid and heat transfer in a realistic human nasal cavity. Eng. Appl. Comput. Fluid Mech. 3(3), 321–335 (2009)
71.
M. Jog, G. McGarry, How frequent are accessory sinus ostia? J. Laryngol. Otol. 117(4), 270–272 (2003)CrossRef
72.
T. Keck, R. Leiacker, A. Heinrich, S. Kuhnemann, G. Rettinger, Humidity and temperature profile in the nasal cavity. Rhinology 38(4), 167–71 (2000)
73.
J.A. Keeler, A. Patki, C.R. Woodard, D.O. Frank-Ito, A computational study of nasal spray deposition pattern in four ethnic groups. J. Aerosol. Med. Pulm. Drug Deliv. 29(2), 153–66 (2016)CrossRef
74.
J. Keir, Why do we have paranasal sinuses? J. Laryngol. Otol. 123(1), 4–8 (2009)CrossRef
75.
R.M. Kellman, C. Schmidt, The paranasal sinuses as a protective crumple zone for the orbit. The Laryngoscope 119(9), 1682–1690 (2009)CrossRef
76.
K. Keyhani, P.W. Scherer, M.M. Mozell, Numerical simulation of airflow in the human nasal cavity. J. Biomech. Eng. 117(4), 429–41 (1995)CrossRef
77.
K. Keyhani, P.W. Scherer, M.M. Mozell, A numerical model of nasal odorant transport for the analysis of human olfaction. J. Theor. Biol. 186(3), 279–301 (1997)CrossRef
78.
D.W. Kim, S.K. Chung, Y. Na, Numerical study on the air conditioning characteristics of the human nasal cavity. Comput. Biol. Med. 86, 18–30 (2017)CrossRef
79.
S.K. Kim, G.E. Heo, A. Seo, Y. Na, S.K. Chung, Correlation between nasal airflow characteristics and clinical relevance of nasal septal deviation to nasal airway obstruction. Respir. Physiol. Neurobiol. 192, 95–101 (2014)CrossRef
80.
S.K. Kim, Y. Na, J.-I. Kim, S.-K. Chung, Patient specific cfd models of nasal airflow: overview of methods and challenges. J. Biomech. 46(2), 299–306 (2013)CrossRef
81.
S.W. Kim, J.H. Mo, J.W. Kim, D.Y. Kim, C.S. Rhee, C.H. Lee, Y.G. Min, Change of nasal function with aging in Korean. Acta Otolaryngol. Suppl. 558, 90–4 (2007)
82.
J. Kimbell, D. Frank, P. Laud, G. Garcia, J. Rhee, Changes in nasal airflow and heat transfer correlate with symptom improvement after surgery for nasal obstruction. J. Biomech. 46(15), 2634–2643 (2013)CrossRef
83.
J.S. Kimbell, S. Basu, G.J. Garcia, D.O. Frank-Ito, F. Lazarow, E. Su, D. Protsenko, Z. Chen, J.S. Rhee, B.J. Wong, Upper airway reconstruction using long-range optical coherence tomography: effects of airway curvature on airflow resistance (Lasers Surg, Med, 2019)
84.
J.S. Kimbell, R.A. Segal, B. Asgharian, B.A. Wong, J.D. Schroeter, J.P. Southall, C.J. Dickens, G. Brace, F.J. Miller, Characterization of deposition from nasal spray devices using a computational fluid dynamics model of the human nasal passages. J. Aerosol Med. 20(1), 59–74 (2007)CrossRef
85.
T. KjÆrgaard, M. Cvancarova, S.K. SteinsvÅg, Relation of nasal air flow to nasal cavity dimensions. Arch. Otolaryngol. Head Neck Surg. 135(6), 565–570 (2009)CrossRef
86.
H. Kumar, R. Jain, R.G. Douglas, M.H. Tawhai, Airflow in the human nasal passage and sinuses of chronic rhinosinusitis subjects. PloS one 11(6), e0156379 (2016)CrossRef
87.
D. Lal, M.L. Gorges, G. Ungkhara, P.M. Reidy, J.P. Corey, Physiological change in nasal patency in response to changes in posture, temperature, and humidity measured by acoustic rhinometry. Am. J. Rhinol. 20(5), 456–62 (2006)CrossRef
88.
C. Lang, S. Grutzenmacher, B. Mlynski, S. Plontke, G. Mlynski, Investigating the nasal cycle using endoscopy, rhinoresistometry, and acoustic rhinometry. Laryngoscope 113(2), 284–9 (2003)CrossRef
89.
T.B. Le, M.G. Moghaddam, B.T. Woodson, G.J.M. Garcia, Airflow limitation in a collapsible model of the human pharynx: physical mechanisms studied with fluid-structure interaction simulations and experiments. Physiol. Rep. 7(10), e14099 (2019)CrossRef
90.
J. Leach, Aesthetics and the hispanic rhinoplasty. Laryngoscope 112(11), 1903–16 (2002)CrossRef
91.
S.C. Leong, X.B. Chen, H.P. Lee, D.Y. Wang, A review of the implications of computational fluid dynamic studies on nasal airflow and physiology. Rhinology 48(2), 139–45 (2010)
92.
S.C. Leong, R. Eccles, A systematic review of the nasal index and the significance of the shape and size of the nose in rhinology. Clin. Otolaryngol. 34(3), 191–198 (2009)CrossRef
93.
C. Li, J. Jiang, H. Dong, K. Zhao, Computational modeling and validation of human nasal airflow under various breathing conditions. J. Biomech. (2017)
94.
J. Lindemann, R. Leiacker, G. Rettinger, T. Keck, Nasal mucosal temperature during respiration. Clin. Otolaryngol. Allied Sci. 27(3), 135–9 (2002)CrossRef
95.
J. Lu, D. Han, L. Zhang, Accuracy evaluation of a numerical simulation model of nasal airflow. Acta Otolaryngol. 134(5), 513–9 (2014)CrossRef
96.
J. Lundberg, G. Settergren, S. Gelinder, J. Lundberg, K. Alving, E. Weitzberg, Inhalation of nasally derived nitric oxide modulates pulmonary function in humans. Acta Physiol. Scandinavica 158(4), 343–347 (1996)CrossRef
97.
J. Lundberg, E. Weitzberg, S. Nordvall, R. Kuylenstierna, J. Lundberg, K. Alving, Primarily nasal origin of exhaled nitric oxide and absence in kartagener’s syndrome. Eur. Respir. J. 7(8), 1501–1504 (1994)CrossRef
98.
J.O. Lundberg, Nitric oxide and the paranasal sinuses. Anat. Rec.: Adv. Integr. Anat. Evol. Biol.: Adv. Integr. Anat. Evol.y Biol. 291(11), 1479–1484 (2008)
99.
J. Ma, J. Dong, Y. Shang, K. Inthavong, J. Tu, D.O. Frank-Ito, Air conditioning analysis among human nasal passages with anterior anatomical variations. Med. Eng. Phys. 57, 19–28 (2018)CrossRef
100.
Maalouf, R., Bequignon, E., Devars du Mayne, M., Zerah-Lancner, F., Isabey, D., Coste, A., Louis, B., and Papon, J. F. A functional tool to differentiate nasal valve collapse from other causes of nasal obstruction: the fried test. J Appl Physiol (1985) 121, 1 (2016), 343–7
101.
M. Maniscalco, E. Weitzberg, J. Sundberg, M. Sofia, J. Lundberg, Assessment of nasal and sinus nitric oxide output using single-breath humming exhalations. Eur. Respir. J. 22(2), 323–329 (2003)CrossRef
102.
W.T. Mcnicholas, M. Coffey, T. Boyle, Effects of nasal airflow on breathing during sleep in normal human. Am. Rev. Respir. Dis. 147, 620–620 (1993)CrossRef
103.
L. Menzel, A. Hess, W. Bloch, O. Michel, K.-D. Schuster, R. Gabler, W. Urban, Temporal nitric oxide dynamics in the paranasal sinuses during humming. J. Appl. Physiol. 98(6), 2064–2071 (2005)CrossRef
104.
Y.G. Min, Y.J. Jang, Measurements of cross-sectional area of the nasal cavity by acoustic rhinometry and ct scanning. Laryngoscope 105(7 Pt 1), 757–9 (1995)CrossRef
105.
R. Moinuddin, B. Mamikoglu, S. Barkatullah, J.P. Corey, Detection of the nasal cycle. Am. J. Rhinol. 15(1), 35–9 (2001)CrossRef
106.
M. Myerson, Natural orifice of the maxillary sinus: Ii. clinical studies. Arch. Otolaryngol. 15(5), 716–733 (1932)
107.
N. Mygind, R. Dahl, Anatomy, physiology and function of the nasal cavities in health and disease. Adv. Drug Deliv. Rev. 29(1–2), 3–12 (1998)CrossRef
108.
Y. Na, K. Kim, S.K. Kim, S.-K. Chung, The quantitative effect of an accessory ostium on ventilation of the maxillary sinus. Respir. Physiol. Neurobiol. 181(1), 62–73 (2012)CrossRef
109.
M.L. Noback, K. Harvati, F. Spoor, Climate-related variation of the human nasal cavity. Am. J. Phys. Anthropol. 145(4), 599–614 (2011)CrossRef
110.
J. Numminen, P. Dastidar, T. Heinonen, T. Karhuketo, M. Rautiainen, Reliability of acoustic rhinometry. Respir. Med. 97(4), 421–7 (2003)
111.
M. Ohki, K. Naito, P. Cole, Dimensions and resistances of the human nose - racial-differences. Laryngoscope 101(3), 276–278 (1991)CrossRef
112.
G. O’Neill, N.S. Tolley, The complexities of nasal airflow - theory and practice. J. Appl. Physiol. (1985) (2019)
113.
J. Osman, F. Großmann, K. Brosien, U. Kertzscher, L. Goubergrits, T. Hildebrandt, Assessment of nasal resistance using computational fluid dynamics. Curr. Dir. Biomed. Eng. 2(1), 617–621 (2016)CrossRef
114.
H.E. Ozel, F. Ozdogan, E. Esen, M.G. Genc, S. Genc, A. Selcuk, The association between septal deviation and the presence of a maxillary accessory ostium. In: International Forum of Allergy & Rhinology, vol. 5, pp. 1177–1180. Wiley Online Library
115.
R.G. Patel, G.J. Garcia, D.O. Frank-Ito, J.S. Kimbell, J.S. Rhee, Simulating the nasal cycle with computational fluid dynamics. Otolaryngol. Head Neck Surg. (2014)
116.
A. Patki, D.O. Frank-Ito, Characterizing human nasal airflow physiologic variables by nasal index. Respir. Physiol. Neurobiol. 232, 66–74 (2016)CrossRef
117.
M. Quadrio, C. Pipolo, S. Corti, R. Lenzi, F. Messina, C. Pesci, G. Felisati, Review of computational fluid dynamics in the assessment of nasal air flow and analysis of its limitations. Eur. Arch. Oto-Rhino-Laryngol. 271(9), 2349–2354 (2014)CrossRef
118.
C.W. Quammen, R.M. Taylor, P. Krajcevski, S. Mitran, A. Enquobahrie, R. Superfine, B. Davis, S. Davis, C. Zdanski, The virtual pediatric airways workbench. In: Studies in Health Technology and Informatics (2016)
119.
T. Radulesco, L. Meister, G. Bouchet, A. Varoquaux, J. Giordano, J. Mancini, P. Dessi, P. Perrier, J. Michel, Correlations between computational fluid dynamics and clinical evaluation of nasal airway obstruction due to septal deviation: An observational study. Clin. Otolaryngol. 44(4), 603–611 (2019)CrossRef
120.
V.H. Ramprasad, D.O. Frank-Ito, A computational analysis of nasal vestibule morphologic variabilities on nasal function. J. Biomech. 49(3), 450–7 (2016)CrossRef
121.
C.E. Rennie, C.M. Hood, E.J. Blenke, R.S. Schroter, D.J. Doorly, H. Jones, D. Towey, N.S. Tolley, Physical and computational modeling of ventilation of the maxillary sinus. Otolaryngol. Head Neck Surg. 145(1), 165–170 (2011)CrossRef
122.
J.S. Rhee, C.D. Sullivan, D.O. Frank, J.S. Kimbell, G.J. Garcia, A systematic review of patient-reported nasal obstruction scores: defining normative and symptomatic ranges in surgical patients. JAMA Facial Plast. Surg. 16(3), 219–25; quiz 232 (2014)
123.
D.G. Roblin, R. Eccles, Normal range for nasal partitioning of airflow determined by nasal spirometry in 100 healthy subjects. Am. J. Rhinol. 17(4), 179–83 (2003)CrossRef
124.
E. Sanmiguel-Rojas, M.A. Burgos, F. Esteban-Ortega, Nasal surgery handled by cfd tools. Int. J. Numer. Method Biomed. Eng. 34(10), e3126 (2018)CrossRef
125.
M.J. Schumacher, Nasal congestion and airway obstruction: The validity of available objective and subjective measures. Curr. Allergy Asthma Rep. 2(3), 245–51 (2002)CrossRef
126.
M.J. Schumacher, Nasal dyspnea: the place of rhinomanometry in its objective assessment. Am. J. Rhinol. 18(1), 41–46 (2004)CrossRef
127.
R.A. Segal, G.M. Kepler, J.S. Kimbell, Effects of differences in nasal anatomy on airflow distribution: a comparison of four individuals at rest. Ann. Biomed. Eng. 36(11), 1870–82 (2008)CrossRef
128.
K.T. Shanley, P. Zamankhan, G. Ahmadi, P.K. Hopke, Y.S. Cheng, Numerical simulations investigating the regional and overall deposition efficiency of the human nasal cavity. Inhal. Toxicol. 20(12), 1093–100 (2008)CrossRef
129.
J. Sozansky, S.M. Houser, The physiological mechanism for sensing nasal airflow: a literature review. Int. Forum Allergy Rhinol. 4(10), 834–8 (2014)CrossRef
130.
F. Stehling, C. Roll, F. Ratjen, H. Grasemann, Nasal nitric oxide to diagnose primary ciliary dyskinesia in newborns. Arch. Dis. Childhood-Fetal Neonatal Ed. 91(3), F233–F233 (2006)CrossRef
131.
R. Subramaniam, R. Richardson, K. Morgan, R. Guilmette, J. Kimbell, Computational fluid dynamics simulations of inspiratory airflow in the human nose and nasopharynx. Inhal. Toxicol. 10, 91–120 (1998)CrossRef
132.
C.D. Sullivan, G.J. Garcia, D.O. Frank-Ito, J.S. Kimbell, J.S. Rhee, Perception of better nasal patency correlates with increased mucosal cooling after surgery for nasal obstruction. Otolaryngol. Head Neck Surg. 150(1), 139–47 (2014)CrossRef
133.
J. Tan, D. Han, J. Wang, T. Liu, T. Wang, H. Zang, Y. Li, X. Wang, Numerical simulation of normal nasal cavity airflow in Chinese adult: a computational flow dynamics model. Eur. Arch. Otorhinolaryngol. 269(3), 881–9 (2012)CrossRef
134.
E. Tarhan, M. Coskun, O. Cakmak, H. Celik, M. Cankurtaran, Acoustic rhinometry in humans: accuracy of nasal passage area estimates, and ability to quantify paranasal sinus volume and ostium size. J. Appl. Physiol. (1985) 99(2), 616–23 (2005)
135.
A. Thomson, L.H.D. Buxton, Man’s nasal index in relation to certain climatic conditions. J. R. Anthropol. Inst. G. B. Ireland 53, 92–122 (1923)
136.
D.L. Vanhille, G.J.M. Garcia, O. Asan, A.A.T. Borojeni, D.O. Frank-Ito, J.S. Kimbell, S.S. Pawar, J.S. Rhee, Virtual surgery for the nasal airway: a preliminary report on decision support and technology acceptance. JAMA Facial Plast. Surg. 20(1), 63–69 (2018)CrossRef
137.
K. Vogt, A.A. Jalowayski, W. Althaus, C. Cao, D. Han, W. Hasse, H. Hoffrichter, R. Mosges, J. Pallanch, K. Shah-Hosseini, K. Peksis, K.D. Wernecke, L. Zhang, P. Zaporoshenko, 4-phase-rhinomanometry (4pr)-basics and practice 2010. Rhinol. Suppl. 21, 1–50 (2010)
138.
D.W. Warren, A.F. Drake, J.U. Davis, Nasal airway in breathing and speech. Cleft Palate-Craniofacial J. 29(6), 511–519 (1992)CrossRef
139.
J.S. Weiner, Nose shape and climate. Am. J. Phys. Anthropol. New Ser. 12(4), 615–618 (1954)CrossRef
140.
E. Weitzberg, J.O. Lundberg, Humming greatly increases nasal nitric oxide. Am. J. Respir. Critical Care Med. 166(2), 144–145 (2002)CrossRef
141.
J. Wen, K. Inthavong, J. Tu, S.M. Wang, Numerical simulations for detailed airflow dynamics in a human nasal cavity. Respir. Physiol. Neurobiol. 161(2), 125–135 (2008)CrossRef
142.
D. Willatt, The evidence for reducing inferior turbinates. Rhinology 47(3), 227–236 (2009)CrossRef
143.
M.H. Wolpoff, Climatic influence on the skeletal nasal aperture. Am. J. Phys. Anthropol. 29(3), 405–23 (1968)CrossRef
144.
D.M. Wootton, H. Luo, S.C. Persak, S. Sin, J.M. McDonough, C.R. Isasi, R. Arens, Computational fluid dynamics endpoints to characterize obstructive sleep apnea syndrome in children. J. Appl. Physiol. (1985) 116(1), 104–12 (2014)
145.
G.-X. Xiong, J.-M. Zhan, H.-Y. Jiang, J.-F. Li, L.-W. Rong, G. Xu, Computational fluid dynamics simulation of airflow in the normal nasal cavity and paranasal sinuses. Am. J. Rhinol. 22, 477–482 (2008)CrossRef
146.
T.R. Yokley, Ecogeographic variation in human nasal passages. Am. J. Phys. Anthropol. 138(1), 11–22 (2009)CrossRef
147.
S. Yu, Y. Liu, X. Sun, S. Li, Influence of nasal structure on the distribution of airflow in nasal cavity. Rhinology 46(2), 137–143 (2008)
148.
K. Zhao, J. Jiang, What is normal nasal airflow? a computational study of 22 healthy adults. Int. Forum Allergy Rhinol. 4(6), 435–46 (2014)CrossRef
149.
K. Zhao, J. Jiang, K. Blacker, B. Lyman, P. Dalton, B.J. Cowart, E.A. Pribitkin, Regional peak mucosal cooling predicts the perception of nasal patency. Laryngoscope 124(3), 589–95 (2014)CrossRef
150.
J.H. Zhu, H.P. Lee, K.M. Lim, B.R. Gordon, D.Y. Wang, Effect of accessory ostia on maxillary sinus ventilation: a computational fluid dynamics (cfd) study. Respir. Physiol. Neurobiol. 183(2), 91–99 (2012)CrossRef
151.
J.H. Zhu, H.P. Lee, K.M. Lim, S.J. Lee, D.Y. Wang, Evaluation and comparison of nasal airway flow patterns among three subjects from caucasian, chinese and indian ethnic groups using computational fluid dynamics simulation. Respir. Physiol. Neurobiol. 175(1), 62–69 (2011)CrossRef
Metadaten
Titel
Clinical Implications of Nasal Airflow Simulations
verfasst von
Dennis Onyeka Frank-Ito
Guilherme Garcia
Copyright-Jahr
2021
Verlag
Springer Singapore
Buch
Clinical and Biomedical Engineering in the Human Nose

Print ISBN: 978-981-15-6715-5

Electronic ISBN: 978-981-15-6716-2

Copyright-Jahr: 2021

DOI
https://doi.org/10.1007/978-981-15-6716-2_8

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