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Erschienen in:

2018 | OriginalPaper | Buchkapitel

3. Clinical Use and Hemostatic Application of Gelatin

verfasst von : Roberto Gazzeri, Marcelo Galarza, Marika Morabito, Alex Alfieri

Erschienen in: Polymer Gels

Verlag: Springer Singapore

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Abstract

Because of the potentially devastating consequences, adequate hemostasis is of paramount importance in all surgical procedures: generalized ooze hemorrhage from the surgical wall cavities, arising from the surface of different organs as liver, kidney, or nervous tissue, can result in considerable blood loss, prolonging surgical times, and with major risk for infection and mortality. Furthermore, hemorrhage may limit visualization in a confined operative field of view, as during endoscopic approaches. Blood-sparing procedures are required for blood loss control to arrest bleeding-related issues and the need for blood transfusions. Classical blood-sparing techniques, such as electrocauterization of the vessels and suturing, are in some cases ineffective. Matrix hemostatic agents are a mixture of a gelatin matrix (bovine or porcine) and a thrombin component mixed together at the time of use. Both components interact synergistically to raise hemostasis and make possible the development of the clot at the bleeding area. In this study, we compare the different hemostatic techniques using the gelatin hemostatic matrix sealant, investigating and reviewing its efficacy and safety in all surgical subspecialties.

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Vorheriges Kapitel Polymer Gels: Molecular Design and Practical Application

Nächstes Kapitel Polysaccharide-Based Polymer Gels and Their Potential Applications

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Titel: Clinical Use and Hemostatic Application of Gelatin
verfasst von: Roberto Gazzeri
Marcelo Galarza
Marika Morabito
Alex Alfieri
Verlag: Springer Singapore
Buch: Polymer Gels
Print ISBN: 978-981-10-6082-3

Electronic ISBN: 978-981-10-6083-0

Copyright-Jahr: 2018
DOI: https://doi.org/10.1007/978-981-10-6083-0_3

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