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Erschienen in:
2010 | OriginalPaper | Buchkapitel
Clustering of Protein Substructures for Discovery of a Novel Class of Sequence-Structure Fragments
verfasst von : Ivana Rudolfova, Jaroslav Zendulka, Matej Lexa
Erschienen in: Information Technology in Bio- and Medical Informatics, ITBAM 2010
Verlag: Springer Berlin Heidelberg
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In this paper, we propose a novel method for clustering of protein substructures that we developed to study the relationships between protein sequences and their corresponding structures. We show the results of the comparison to other commonly used methods for clustering of protein structures. Finally, we outline a procedure for finding sequence profiles that tend to occur in more than one structural conformation but the number of their structural conformations is limited. This procedure is based on our method for protein substructure clustering.