Skip to main content

2016 | OriginalPaper | Buchkapitel

Complex Biological Systems

verfasst von : Andrew J. Spakowitz

Erschienen in: Handbook of Science and Technology Convergence

Verlag: Springer International Publishing

Aktivieren Sie unsere intelligente Suche um passende Fachinhalte oder Patente zu finden.

search-config
loading …

Abstract

Biological entities range in scale and complexity from the simplest viruses to multicellular organisms with specialized cells, tissues, and organs. Within a cell of any organism, there are an enormous number of biomolecular complexes that perform physical and chemical tasks with remarkable speed and fidelity. The goals in many nanoscale engineering applications mirror the major challenges that Nature has overcome in the engineering of biomolecular systems. As such, there exist some basic paradigms of biological design that can either be mimicked or exploited for nanoengineering applications. In this chapter, several paradigms for biological control at the nanoscale are identified, and several key examples are leveraged to identify how these ideas can be used in a range of engineered systems.

Sie haben noch keine Lizenz? Dann Informieren Sie sich jetzt über unsere Produkte:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

  • über 102.000 Bücher
  • über 537 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Maschinenbau + Werkstoffe
  • Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 390 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Maschinenbau + Werkstoffe




 

Jetzt Wissensvorsprung sichern!

Springer Professional "Wirtschaft"

Online-Abonnement

Mit Springer Professional "Wirtschaft" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 340 Zeitschriften

aus folgenden Fachgebieten:

  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Versicherung + Risiko




Jetzt Wissensvorsprung sichern!

Literatur
Zurück zum Zitat Baneyx F (1999) Recombinant protein expression in Escherichia coli. Curr Opin Biotechnol 10(5):411–421CrossRef Baneyx F (1999) Recombinant protein expression in Escherichia coli. Curr Opin Biotechnol 10(5):411–421CrossRef
Zurück zum Zitat Bustamante C, Bryant Z, Smith SB (2003) Ten years of tension: single-molecule DNA mechanics. Nature 421(6921):423–427CrossRef Bustamante C, Bryant Z, Smith SB (2003) Ten years of tension: single-molecule DNA mechanics. Nature 421(6921):423–427CrossRef
Zurück zum Zitat Cordella N, Lampo TJ, Melosh N, Spakowitz AJ (2015) Membrane indentation triggers clathrin lattice reorganization and fluidization. Soft Matter 11(3):439–448CrossRef Cordella N, Lampo TJ, Melosh N, Spakowitz AJ (2015) Membrane indentation triggers clathrin lattice reorganization and fluidization. Soft Matter 11(3):439–448CrossRef
Zurück zum Zitat de Gennes P-G (1971) Reptation of a polymer chain in the presence of fixed obstacles. J Chem Phys 55(2):572–579CrossRef de Gennes P-G (1971) Reptation of a polymer chain in the presence of fixed obstacles. J Chem Phys 55(2):572–579CrossRef
Zurück zum Zitat Doi M, Edwards SF (1999) The theory of polymer dynamics. Oxford University Press, New York Doi M, Edwards SF (1999) The theory of polymer dynamics. Oxford University Press, New York
Zurück zum Zitat Euler L. Elementa doctrine solidorum. Novi comm. acad. scientiarum imperialis petropolitanae 4:109–160, 1752–1753 Euler L. Elementa doctrine solidorum. Novi comm. acad. scientiarum imperialis petropolitanae 4:109–160, 1752–1753
Zurück zum Zitat Flory PJ (1953) Principles of polymer chemistry. Cornell University Press, Ithaca Flory PJ (1953) Principles of polymer chemistry. Cornell University Press, Ithaca
Zurück zum Zitat Greenleaf WJ, Woodside MT, Block SM (2007) High-resolution, single-molecule measurements of biomolecular motion. Annu Rev Biophys Biomol Struct 36:171CrossRef Greenleaf WJ, Woodside MT, Block SM (2007) High-resolution, single-molecule measurements of biomolecular motion. Annu Rev Biophys Biomol Struct 36:171CrossRef
Zurück zum Zitat Karunakaran A (2007) Single molecule studies of a viral DNA packaging motor. University of California, Berkeley Karunakaran A (2007) Single molecule studies of a viral DNA packaging motor. University of California, Berkeley
Zurück zum Zitat Langer R, Tirrell DA (2004) Designing materials for biology and medicine. Nature 428(6982):487–492CrossRef Langer R, Tirrell DA (2004) Designing materials for biology and medicine. Nature 428(6982):487–492CrossRef
Zurück zum Zitat Liu W, Brock A, Chen S, Chen S, Schultz PG (2007) Genetic incorporation of unnatural amino acids into proteins in mammalian cells. Nat Methods 4(3):239–244CrossRef Liu W, Brock A, Chen S, Chen S, Schultz PG (2007) Genetic incorporation of unnatural amino acids into proteins in mammalian cells. Nat Methods 4(3):239–244CrossRef
Zurück zum Zitat Marras AE, Zhou L, Hai-Jun S, Castro CE (2015) Programmable motion of DNA origami mechanisms. Proc Natl Acad Sci 112(3):713–718CrossRef Marras AE, Zhou L, Hai-Jun S, Castro CE (2015) Programmable motion of DNA origami mechanisms. Proc Natl Acad Sci 112(3):713–718CrossRef
Zurück zum Zitat Park PJ (2009) Chip-seq: advantages and challenges of a maturing technology. Nat Rev Genet 10(10):669–680CrossRef Park PJ (2009) Chip-seq: advantages and challenges of a maturing technology. Nat Rev Genet 10(10):669–680CrossRef
Zurück zum Zitat Pavani SRP, Thompson MA, Biteen JS, Lord SJ, Liu N, Twieg RJ, Rafael P, Moerner WE (2009) Three-dimensional, single-molecule fluorescence imaging beyond the diffraction limit by using a double-helix point spread function. Proc Natl Acad Sci 106(9):2995–2999CrossRef Pavani SRP, Thompson MA, Biteen JS, Lord SJ, Liu N, Twieg RJ, Rafael P, Moerner WE (2009) Three-dimensional, single-molecule fluorescence imaging beyond the diffraction limit by using a double-helix point spread function. Proc Natl Acad Sci 106(9):2995–2999CrossRef
Zurück zum Zitat Qi LS, Larson MH, Gilbert LA, Doudna JA, Weissman JS, Arkin AP, Lim WA (2013) Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression. Cell 152(5):1173–1183CrossRef Qi LS, Larson MH, Gilbert LA, Doudna JA, Weissman JS, Arkin AP, Lim WA (2013) Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression. Cell 152(5):1173–1183CrossRef
Zurück zum Zitat Reece RJ, Maxwell A, Wang JC (1991) DNA gyrase: structure and function. Crit Rev Biochem Mol Biol 26(3–4):335–375CrossRef Reece RJ, Maxwell A, Wang JC (1991) DNA gyrase: structure and function. Crit Rev Biochem Mol Biol 26(3–4):335–375CrossRef
Zurück zum Zitat Rothemund PWK (2006) Folding DNA to create nanoscale shapes and patterns. Nature 440(7082):297–302CrossRef Rothemund PWK (2006) Folding DNA to create nanoscale shapes and patterns. Nature 440(7082):297–302CrossRef
Zurück zum Zitat Schoen AP, Schoen DT, Huggins KNL, Arunagirinathan MA, Heilshorn SC (2011) Template engineering through epitope recognition: a modular, biomimetic strategy for inorganic nanomaterial synthesis. J Am Chem Soc 133(45):18202–18207CrossRef Schoen AP, Schoen DT, Huggins KNL, Arunagirinathan MA, Heilshorn SC (2011) Template engineering through epitope recognition: a modular, biomimetic strategy for inorganic nanomaterial synthesis. J Am Chem Soc 133(45):18202–18207CrossRef
Zurück zum Zitat Seeman NC, Belcher AM (2002) Emulating biology: building nanostructures from the bottom up. Proc Natl Acad Sci U S A 99(Suppl 2):6451–6455CrossRef Seeman NC, Belcher AM (2002) Emulating biology: building nanostructures from the bottom up. Proc Natl Acad Sci U S A 99(Suppl 2):6451–6455CrossRef
Zurück zum Zitat Shtengel G, Galbraith JA, Galbraith CG, Lippincott-Schwartz J, Gillette JM, Manley S, Sougrat R, Waterman CM, Kanchanawong P, Davidson MW et al (2009) Interferometric fluorescent super-resolution microscopy resolves 3D cellular ultrastructure. Proc Natl Acad Sci 106(9):3125–3130CrossRef Shtengel G, Galbraith JA, Galbraith CG, Lippincott-Schwartz J, Gillette JM, Manley S, Sougrat R, Waterman CM, Kanchanawong P, Davidson MW et al (2009) Interferometric fluorescent super-resolution microscopy resolves 3D cellular ultrastructure. Proc Natl Acad Sci 106(9):3125–3130CrossRef
Zurück zum Zitat Smith DE, Tans SJ, Smith SB, Grimes S, Anderson DL, Bustamante C (2001) The bacteriophage ϕ29 portal motor can package DNA against a large internal force. Nature 413(6857):748–752CrossRef Smith DE, Tans SJ, Smith SB, Grimes S, Anderson DL, Bustamante C (2001) The bacteriophage ϕ29 portal motor can package DNA against a large internal force. Nature 413(6857):748–752CrossRef
Zurück zum Zitat Wang JC, Giaever GN (1988) Action at a distance along a DNA. Science 240(4850):300–304CrossRef Wang JC, Giaever GN (1988) Action at a distance along a DNA. Science 240(4850):300–304CrossRef
Zurück zum Zitat Weiner S, De Yoreo JJ, Dove PM (2003) Biomineralization. Mineralogical Society of America Weiner S, De Yoreo JJ, Dove PM (2003) Biomineralization. Mineralogical Society of America
Metadaten
Titel
Complex Biological Systems
verfasst von
Andrew J. Spakowitz
Copyright-Jahr
2016
DOI
https://doi.org/10.1007/978-3-319-07052-0_81