Cortical activity exhibits complex, persistent self-sustained dynamics, which is hypothesised to support the brain’s sophisticated processing capabilities. Prior studies have shown how complex activity can be sustained for some time in spiking neural network models, but network activity in these models resembled high firing rate seizure which would eventually fail, leading to indefinite quiescence. We present a spiking network model of cortex innervated by diffuse thalamic projections, called the Complex Spiking Model (CSM). The model exhibits persistent, self-sustained, non-periodic, complex dynamics at low firing rates. Multiple network configurations were tested, systematically varying diffuse excitation from the thalamus, strength of the local cortical inhibition and excitation, neighbourhood diameters, synaptic efficacies and synaptic current time constants. Complex activity in all the network configurations depended strongly upon the strength of the diffuse excitation from the thalamus. We propose that diffuse thalamic projections to cortex facilitate complex cortical dynamics and are likely to be an important factor in the support of cognitive functions.
Weitere Kapitel dieses Buchs durch Wischen aufrufen
Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten
Sie möchten Zugang zu diesem Inhalt erhalten? Dann informieren Sie sich jetzt über unsere Produkte:
- Complex Spiking Models: A Role for Diffuse Thalamic Projections in Complex Cortical Activity
- Springer Berlin Heidelberg