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1988 | OriginalPaper | Buchkapitel

Current Problems in Quantitative Structure Activity Relationships

verfasst von : Hugo Kubinyi

Erschienen in: Physical Property Prediction in Organic Chemistry

Verlag: Springer Berlin Heidelberg

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Quantitative structure activity relationships (QSAR) are to be understood as a consequence of the fact that the interactions of drugs with their biological counterparts are determined by intermolecular forces. Thus the structural dependence of biological activities can be described either by physicochemical parameters (Hansch analysis) or by indicator variables encoding different structural features (Free Wilson analysis, pattern recognition).

Metadaten
Titel
Current Problems in Quantitative Structure Activity Relationships
verfasst von
Hugo Kubinyi
Copyright-Jahr
1988
Verlag
Springer Berlin Heidelberg
DOI
https://doi.org/10.1007/978-3-642-74140-1_17