Design of a Device for Recording Bioelectric Signals with Surface Electrodes, in the Evaluation of the Effect of Ultraviolet Radiation on a Tissue

The accepted methodology by regulatory agencies to determine the efficacy of sunscreen products makes use of healthy human volunteers who are exposed to radiation. In order to find an alternative to these types of evaluations, the effect of exposure to UV radiation was investigated in an ex vivo pig skin model on the bioelectrical signals of the tissue in terms of energy and impedance. A system was implemented using the measurements configuration of 4 electrodes (Two electrostimulation electrodes and two electrodes for the signals acquisition all of them were silver cup electrodes) and a mathematical model was established in relation to electrical change as a function of exposure time. As a result, an attenuation of the energy response signal relative to the non-irradiated tissue was obtained, as well as impedance values after irradiation. This behavior is directly related to damage in the tissue structure. The results allow to conclude that the device can quantify the effect caused by radiation on the electrical properties of an ex vivo tissue and are promising in the understanding of the phenomena associated with the electrical response of a tissue to ultraviolet radiation.