1996 | OriginalPaper | Buchkapitel
Determination of Elastic Parameters of Pharmaceutical Materials Using a Fiber Interferometer
verfasst von : Jarmo Hietanen, Markku Oksanen, Pekka Raatikainen, Mauri Luukkala, Pasi Raatikainen, Jarkko Ketolainen, Petteri Paronen
Erschienen in: Review of Progress in Quantitative Nondestructive Evaluation
Verlag: Springer US
Enthalten in: Professional Book Archive
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In the development of pharmaceutical products the elastic parameters of excipients are studied to assume drug safety. The excipients and their coating affect the emission properties of the drug. To determine the elastic parameters, the powder bond material is first pressed into the shape of a rectangular beam. In commonly used 3-point bending measurements, there is a tendency to move from the elastic bending regime to the plastic bending regime which necessarily changes the result for the elastic parameter in question [1]. Another available method is based on photoacoustics, but it is limited to the elastic regime [2]. The goal of this study is to create a system that would allow for high accuracy testing of these materials from the low force elastic to high force plastic regimes while using the same apparatus.