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2014 | OriginalPaper | Buchkapitel

2. Development of Patch Clamping

verfasst von : Majid Malboubi, Kyle Jiang

Erschienen in: Gigaseal Formation in Patch Clamping

Verlag: Springer Berlin Heidelberg

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Abstract

Patch clamping was first introduced into biophysical studies by Neher and Sakmann [1] in 1976 and was soon expanded to many other fields such as biology and medicine. The technique not only allowed the detection of single-channel currents in biological membranes for the first time but also enabled higher current resolution, direct membrane patch potential control, and physical isolation of membrane patches [2]. The development of the patch clamp method was honoured with a Nobel Prize in 1991.

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Metadaten
Titel
Development of Patch Clamping
verfasst von
Majid Malboubi
Kyle Jiang
Copyright-Jahr
2014
Verlag
Springer Berlin Heidelberg
DOI
https://doi.org/10.1007/978-3-642-39128-6_2

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