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Erschienen in:
2010 | OriginalPaper | Buchkapitel
Double Network Hydrogels as Tough, Durable Tissue Substitutes
verfasst von : Takayuki Murosaki, Jian Ping Gong
Erschienen in: Biomedical Applications of Hydrogels Handbook
Verlag: Springer New York
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Abstract
Hydrogels are soft and wet materials with a wide range of biomedical applications to make tissue due to their unique properties, such as phase-transition, chemo-mechanical behavior, stimuli-responsiveness, and low surface friction. However, most hydrogels are mechanically too weak to be used practically in load-bearing applications. Double Network (DN) hydrogels are composed of both rigid and soft hydrogels networks, and are expected to perform better under mechanical loads. The DN gels exhibit a 0.1–1 MPa elastic modulus, 60 MPa compressive fracture stress, 3,000% of tensile strain, and 2,500 J/m2 of fracture energy. These soft and wet gels materials with high mechanical strength, low surface friction, and high deterioration-resistance properties are good candidates as load-bearing tissue substitutes, such as auricular cartilage.