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Journal of Sol-Gel Science and Technology
Erschienen in: Journal of Sol-Gel Science and Technology 1/2018

18.02.2017 | Original Paper: Sol-gel and hybrid materials for biological and health (medical) applications

Effect of polyethylene glycol additives on structure, stability, and biocatalytic activity of ormosil sol–gel encapsulated yeast cells

verfasst von: D. G. Lavrova, O. A. Kamanina, A. V. Machulin, N. E. Suzina, V. A. Alferov, O. N. Ponamoreva

Erschienen in: Journal of Sol-Gel Science and Technology | Ausgabe 1/2018

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Abstract

Biohybrid materials based on ormosil encapsulated yeast cells were synthesized through a one-step sol–gel route with base-catalyst (NaF) using tetraethoxysilane (TEOS), methyltriethoxysilane (MTES) and polyethylene glycol (PEG) with different molar weights as a structure-controlling agent. Phase contrast microscopy and scanning electron microscopy were employed to evidence possible structures of the materials. The addition of PEG during cell encapsulation has induced structural changes within the biohybrids, which depend on PEG molecular weights. The biocatalytic activity of the living hybrids has been investigated by a biosensor which was based on the Clark-type oxygen electrode.

Graphical Abstract

https://static-content.springer.com/image/art%3A10.1007%2Fs10971-017-4333-z/MediaObjects/10971_2017_4333_Figa_HTML.gif
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Metadaten
Titel
Effect of polyethylene glycol additives on structure, stability, and biocatalytic activity of ormosil sol–gel encapsulated yeast cells
verfasst von
D. G. Lavrova
O. A. Kamanina
A. V. Machulin
N. E. Suzina
V. A. Alferov
O. N. Ponamoreva
Publikationsdatum
18.02.2017
Verlag
Springer US
Erschienen in
Journal of Sol-Gel Science and Technology / Ausgabe 1/2018
Print ISSN: 0928-0707
Elektronische ISSN: 1573-4846
DOI
https://doi.org/10.1007/s10971-017-4333-z

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