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Erschienen in:
2008 | OriginalPaper | Buchkapitel
Effects of electromagnetic pulse on the vimentin of mice testes
verfasst von : Xiao-Wu Wang, Chang-Hong Shi, Gui-Rong Ding, Tao Zhao, Li-Hua Zeng, Jie Zhang, Xue-Jun Xie, Guo-Zhen Guo
Erschienen in: 7th Asian-Pacific Conference on Medical and Biological Engineering
Verlag: Springer Berlin Heidelberg
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AIM To investigate the changes of the mice testes and the tight junction (Tj) relative molecular and to identify the molecular mechanisms of the mice blood-testis-barrier (BTB) permea-bility increasing after the mice were exposed to electromagnetic pulse (EMP). METHODS Observe the changes vimentin of the mice testes by laser scanning confocal technique. RESULTS After the 200kVm
−1
EMP (the accumulative pulse times was 200) exposure, the vimentin in sustentacular cells of testis became irregularly shortened and derangement, and the intensity of immuno-fluorescence also showed ununiformity compared with control. CONCLUSION The increasing of mice BTB permeability perhaps caused by the changing of vimentin.