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Erschienen in: Journal of Coatings Technology and Research 6/2022

13.07.2022

Effects of hydroxyapatite coatings on enhanced corrosion protection and cytocompatibility of high-purity magnesium

verfasst von: Qingyun Fu, Mingcheng Feng, Jian Li, Nian He, Wenjing Li, Jingyao Li, Junjie Yang, Weihong Jin, Wei Li, Zhentao Yu

Erschienen in: Journal of Coatings Technology and Research | Ausgabe 6/2022

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Abstract

Magnesium (Mg) and its alloys are promising materials for temporary biomedical implants such as bone fracture fixation devices. Unfortunately, rapid degradation in the physiological environment and cytotoxicity have impeded their clinical use. Hydroxyapatite (HA) coatings synthesized via ethylenediaminetetraacetic acid calcium disodium salt hydrate (EDTA-Ca) and potassium dihydrogen phosphate (KH2PO4) have emerged as one effective strategy to enhance the corrosion resistance and biocompatibility of Mg and its alloys. However, effects of the concentrations of EDTA-Ca and KH2PO4 on the morphology, corrosion protection, and biocompatibility of HA coatings remain unclear. In this study, the morphology, thickness, corrosion protection, and cytocompatibility of the HA coatings fabricated on high-purity Mg with different concentrations of the synthetic solution are investigated. Our results show that the fabricated coatings are composed of a dome-shaped outer HA layer and an inner Mg(OH)2 layer. With decreasing the concentrations of the synthetic solution, the HA and Mg(OH)2 layers become thinner and thicker, respectively, and the corrosion resistance and cytocompatibility of the coated Mg become better. The formation mechanism of the prepared coatings and relationships between the concentrations of the synthetic solution and the corrosion and biological characteristics are also discussed.

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Metadaten
Titel
Effects of hydroxyapatite coatings on enhanced corrosion protection and cytocompatibility of high-purity magnesium
verfasst von
Qingyun Fu
Mingcheng Feng
Jian Li
Nian He
Wenjing Li
Jingyao Li
Junjie Yang
Weihong Jin
Wei Li
Zhentao Yu
Publikationsdatum
13.07.2022
Verlag
Springer US
Erschienen in
Journal of Coatings Technology and Research / Ausgabe 6/2022
Print ISSN: 1547-0091
Elektronische ISSN: 1935-3804
DOI
https://doi.org/10.1007/s11998-022-00646-6

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