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α-d-Phosphoglucomutase: A Promising Target in Carbohydrate Formation

  • 2025
  • OriginalPaper
  • Chapter
Published in:
Authors
Gabriel Alves De Jong
Carlos Henrique Tomich de Paula da Silva
Published in
Computational Intelligence in Drug Development
Publisher
Springer Nature Switzerland

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Abstract

This chapter delves into the critical role of α-d-Phosphoglucomutase (PGM) in carbohydrate metabolism, highlighting its potential as a drug target. The text explores the enzyme's catalytic mechanism, sequence, and structural features, as well as its association with virulence in various pathogenic organisms. It also discusses the enzyme's potential in cancer pathogenesis and the development of effective inhibitors. The chapter concludes with insights into the future of PGM-targeted therapies, making it a comprehensive resource for professionals in the field.
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previous chapter Enzymes as Targets for Disease Control: From Discovery to Application
Title
α-d-Phosphoglucomutase: A Promising Target in Carbohydrate Formation
Authors
Gabriel Alves De Jong
Carlos Henrique Tomich de Paula da Silva
Copyright Year
2025
Book
Computational Intelligence in Drug Development

Print ISBN: 978-3-032-07365-5

Electronic ISBN: 978-3-032-07366-2

Copyright Year: 2025

DOI
https://doi.org/10.1007/978-3-032-07366-2_9
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