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Published in: International Journal of Computer Assisted Radiology and Surgery 8/2021

31-05-2021 | Short communication

3D axial-attention for lung nodule classification

Authors: Mundher Al-Shabi, Kelvin Shak, Maxine Tan

Published in: International Journal of Computer Assisted Radiology and Surgery | Issue 8/2021

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Abstract

Purpose

In recent years, Non-Local-based methods have been successfully applied to lung nodule classification. However, these methods offer 2D attention or limited 3D attention to low-resolution feature maps. Moreover, they still depend on a convenient local filter such as convolution as full 3D attention is expensive to compute and requires a big dataset, which might not be available.

Methods

We propose to use 3D Axial-Attention, which requires a fraction of the computing power of a regular Non-Local network (i.e., self-attention). Unlike a regular Non-Local network, the 3D Axial-Attention network applies the attention operation to each axis separately. Additionally, we solve the invariant position problem of the Non-Local network by proposing to add 3D positional encoding to shared embeddings.

Results

We validated the proposed method on 442 benign nodules and 406 malignant nodules, extracted from the public LIDC-IDRI dataset by following a rigorous experimental setup using only nodules annotated by at least three radiologists. Our results show that the 3D Axial-Attention model achieves state-of-the-art performance on all evaluation metrics, including AUC and Accuracy.

Conclusions

The proposed model provides full 3D attention, whereby every element (i.e., pixel) in the 3D volume space attends to every other element in the nodule effectively. Thus, the 3D Axial-Attention network can be used in all layers without the need for local filters. The experimental results show the importance of full 3D attention for classifying lung nodules.

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Literature
1.
go back to reference American Cancer Society (2020) Cancer Facts & Figures American Cancer Society (2020) Cancer Facts & Figures
7.
10.
go back to reference Wang X, Girshick R, Gupta A, He K (2018) Non-local Neural Networks. In: 2018 IEEE/CVF Conference on Computer Vision and Pattern Recognition. IEEE, pp 7794–7803 Wang X, Girshick R, Gupta A, He K (2018) Non-local Neural Networks. In: 2018 IEEE/CVF Conference on Computer Vision and Pattern Recognition. IEEE, pp 7794–7803
11.
go back to reference Vaswani A, Shazeer N, Parmar N, Uszkoreit J, Jones L, Gomez AN, Kaiser Ł ukasz, Polosukhin I (2017) Attention is All you Need. In: Guyon I, Luxburg U V, Bengio S, Wallach H, Fergus R, Vishwanathan S, Garnett R (eds) Advances in Neural Information Processing Systems 30. Curran Associates, Inc., pp 5998–6008 Vaswani A, Shazeer N, Parmar N, Uszkoreit J, Jones L, Gomez AN, Kaiser Ł ukasz, Polosukhin I (2017) Attention is All you Need. In: Guyon I, Luxburg U V, Bengio S, Wallach H, Fergus R, Vishwanathan S, Garnett R (eds) Advances in Neural Information Processing Systems 30. Curran Associates, Inc., pp 5998–6008
12.
go back to reference Al-Shabi M, Shak K, Tan M (2020) ProCAN: Progressive Growing Channel Attentive Non-Local Network for Lung Nodule Classification. ArXiv:2010.15417 Al-Shabi M, Shak K, Tan M (2020) ProCAN: Progressive Growing Channel Attentive Non-Local Network for Lung Nodule Classification. ArXiv:​2010.​15417
13.
go back to reference Ho J, Kalchbrenner N, Weissenborn D, Salimans T (2019) Axial Attention in Multidimensional Transformers. ArXiv:1912.12180 Ho J, Kalchbrenner N, Weissenborn D, Salimans T (2019) Axial Attention in Multidimensional Transformers. ArXiv:​1912.​12180
14.
go back to reference Armato SG, McLennan G, Bidaut L, McNitt-Gray MF, Meyer CR, Reeves AP, Zhao B, Aberle DR, Henschke CI, Hoffman EA, Kazerooni EA, MacMahon H, Van Beek EJR, Yankelevitz D, Biancardi AM, Bland PH, Brown MS, Engelmann RM, Laderach GE, Max D, Pais RC, Qing DPY, Roberts RY, Smith AR, Starkey A, Batra P, Caligiuri P, Farooqi A, Gladish GW, Jude CM, Munden RF, Petkovska I, Quint LE, Schwartz LH, Sundaram B, Dodd LE, Fenimore C, Gur D, Petrick N, Freymann J, Kirby J, Hughes B, Vande Casteele A, Gupte S, Sallam M, Heath MD, Kuhn MH, Dharaiya E, Burns R, Fryd DS, Salganicoff M, Anand V, Shreter U, Vastagh S, Croft BY, Clarke LP (2011) The Lung Image Database Consortium (LIDC) and Image Database Resource Initiative (IDRI): a completed reference database of lung nodules on CT scans. Med Phys 38:915–931. https://doi.org/10.1118/1.3528204CrossRefPubMedPubMedCentral Armato SG, McLennan G, Bidaut L, McNitt-Gray MF, Meyer CR, Reeves AP, Zhao B, Aberle DR, Henschke CI, Hoffman EA, Kazerooni EA, MacMahon H, Van Beek EJR, Yankelevitz D, Biancardi AM, Bland PH, Brown MS, Engelmann RM, Laderach GE, Max D, Pais RC, Qing DPY, Roberts RY, Smith AR, Starkey A, Batra P, Caligiuri P, Farooqi A, Gladish GW, Jude CM, Munden RF, Petkovska I, Quint LE, Schwartz LH, Sundaram B, Dodd LE, Fenimore C, Gur D, Petrick N, Freymann J, Kirby J, Hughes B, Vande Casteele A, Gupte S, Sallam M, Heath MD, Kuhn MH, Dharaiya E, Burns R, Fryd DS, Salganicoff M, Anand V, Shreter U, Vastagh S, Croft BY, Clarke LP (2011) The Lung Image Database Consortium (LIDC) and Image Database Resource Initiative (IDRI): a completed reference database of lung nodules on CT scans. Med Phys 38:915–931. https://​doi.​org/​10.​1118/​1.​3528204CrossRefPubMedPubMedCentral
15.
go back to reference Ba J, Kiros J, Hinton GE (2016) Layer normalization. ArXiv:1607.06450 Ba J, Kiros J, Hinton GE (2016) Layer normalization. ArXiv:​1607.​06450
17.
go back to reference Kingma DP, Ba J (2015) Adam: A Method for Stochastic Optimization. In: Bengio Y, LeCun Y (eds) 3rd International Conference on Learning Representations, ICLR 2015,San Diego, CA, USA, May 7–9, 2015, Conference Track Proceedings Kingma DP, Ba J (2015) Adam: A Method for Stochastic Optimization. In: Bengio Y, LeCun Y (eds) 3rd International Conference on Learning Representations, ICLR 2015,San Diego, CA, USA, May 7–9, 2015, Conference Track Proceedings
18.
go back to reference Glorot X, Bengio Y (2010) Understanding the difficulty of training deep feedforward neural networks. In: Proceedings of the Thirteenth International Conference on Artificial Intelligence and Statistics. JMLR Workshop and Conference Proceedings, pp 249–256 Glorot X, Bengio Y (2010) Understanding the difficulty of training deep feedforward neural networks. In: Proceedings of the Thirteenth International Conference on Artificial Intelligence and Statistics. JMLR Workshop and Conference Proceedings, pp 249–256
Metadata
Title
3D axial-attention for lung nodule classification
Authors
Mundher Al-Shabi
Kelvin Shak
Maxine Tan
Publication date
31-05-2021
Publisher
Springer International Publishing
Published in
International Journal of Computer Assisted Radiology and Surgery / Issue 8/2021
Print ISSN: 1861-6410
Electronic ISSN: 1861-6429
DOI
https://doi.org/10.1007/s11548-021-02415-z

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