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2025 | OriginalPaper | Chapter

A Low Power High Input Impedance CMOS Biopotential Integrated Preamplifier

Authors : Porika Nandini, Jatoth Deepak Naik, Pradeep Gorre, Alaaddin Al-Shidaifat, Mohammad Khaleqi Qaleh Jooq, Sandeep Kumar, Hanjung Song

Published in: Proceedings of Third International Conference on Computational Electronics for Wireless Communications

Publisher: Springer Nature Singapore

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Abstract

The front-end amplifier is an essential component in neurological monitoring systems for signal detection and preprocessing, affecting besides the quality of the biosignal but additionally detector size and usage of power. In this study, a unique dual feedback loop-controlled method is presented to account for both signal leakage through the input bias network and leakage currents produced by low-noise amplifiers when they are implemented as integrated circuits. The Front-End Amplifier (FEA) is guaranteed to retain a significant input impedance despite all manufacturing and operating changes thanks to this loop design. Results from simulations using the 65 nm CMOS technology are given. This FEA uses 3.14 μW and accomplishes an input impedance of 2 TΩ and input referred noise of 23 pV/√Hz.

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Literature
1.
go back to reference Grossberg ST (2012) Studies of mind and brain: neural principles of learning, perception, development, cognition, and motor control, vol 70. Springer Science & Business Media Grossberg ST (2012) Studies of mind and brain: neural principles of learning, perception, development, cognition, and motor control, vol 70. Springer Science & Business Media
2.
go back to reference Mohseni P, Najafi K (2004) A fully integrated neural recording amplifier with DC input stabilization. IEEE Trans Biomed Eng 51(5):832–837 Mohseni P, Najafi K (2004) A fully integrated neural recording amplifier with DC input stabilization. IEEE Trans Biomed Eng 51(5):832–837
3.
go back to reference Harrison R, Charles C (2003) A low-power low-noise CMOS amplifier for neural recording applications. IEEE J Solid-State Circ 38(6):958–965 Harrison R, Charles C (2003) A low-power low-noise CMOS amplifier for neural recording applications. IEEE J Solid-State Circ 38(6):958–965
4.
go back to reference Matteo V, Esposito E (2003) Biochemical and therapeutic effects of antioxidants in the treatment of Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis. Curr Drug Targets-CNS & Neurol Disorders 2(2):95–107CrossRef Matteo V, Esposito E (2003) Biochemical and therapeutic effects of antioxidants in the treatment of Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis. Curr Drug Targets-CNS & Neurol Disorders 2(2):95–107CrossRef
5.
go back to reference Pachitariu M et al (2016) Kilosort: realtime spike-sorting for extracellular electrophysiology with hundreds of channels. BioRxiv, 061481 Pachitariu M et al (2016) Kilosort: realtime spike-sorting for extracellular electrophysiology with hundreds of channels. BioRxiv, 061481
6.
go back to reference Song S, Rooijakkers M, Harpe P, Rabotti C, Mischi M, van Roermund A, Cantatore E (2015) A low-voltage chopper-stabilized amplifier for fetal ECG monitoring with a 1.41 power efficiency factor. IEEE Trans Biomed Circ Syst 9(2):237–247 Song S, Rooijakkers M, Harpe P, Rabotti C, Mischi M, van Roermund A, Cantatore E (2015) A low-voltage chopper-stabilized amplifier for fetal ECG monitoring with a 1.41 power efficiency factor. IEEE Trans Biomed Circ Syst 9(2):237–247
7.
go back to reference Toth L, Tsividis Y (2003) Generalization of the principle of chopper stabilization. IEEE Trans Circ Syst I Fundam Theory 50(8):975–983 Toth L, Tsividis Y (2003) Generalization of the principle of chopper stabilization. IEEE Trans Circ Syst I Fundam Theory 50(8):975–983
8.
go back to reference Destexhe A, Rudolph M, Paré D (2003) The high-conductance state of neocortical neurons in vivo. Nat Rev Neurosci 4(9):739–751CrossRef Destexhe A, Rudolph M, Paré D (2003) The high-conductance state of neocortical neurons in vivo. Nat Rev Neurosci 4(9):739–751CrossRef
9.
go back to reference Ratner BD (2011) The biocompatibility manifesto: biocompatibility for the twenty-first century. J Cardiovasc Transl Res 4:523–527 Ratner BD (2011) The biocompatibility manifesto: biocompatibility for the twenty-first century. J Cardiovasc Transl Res 4:523–527
10.
go back to reference Longden TA et al (2017) Capillary K+-sensing initiates retrograde hyperpolarization to increase local cerebral blood flow. Nat Neurosci 20(5):717–726 Longden TA et al (2017) Capillary K+-sensing initiates retrograde hyperpolarization to increase local cerebral blood flow. Nat Neurosci 20(5):717–726
11.
go back to reference Naik JD, Gorre P, Akuri NG et al (2022) High-performance graphene FET integrated front-end amplifier using pseudo-resistor technique for neuro-prosthetic diagnosis. BioChip J 16:270–279CrossRef Naik JD, Gorre P, Akuri NG et al (2022) High-performance graphene FET integrated front-end amplifier using pseudo-resistor technique for neuro-prosthetic diagnosis. BioChip J 16:270–279CrossRef
12.
go back to reference Zhou Z, Warr PA (2016) A high ınput ımpedance low noise ıntegrated front-end amplifier for neural monitoring. IEEE Trans Biomed Circ Syst 10(6):1079–1086 Zhou Z, Warr PA (2016) A high ınput ımpedance low noise ıntegrated front-end amplifier for neural monitoring. IEEE Trans Biomed Circ Syst 10(6):1079–1086
13.
go back to reference Chi Y, Maier C, Cauwenberghs G (2011) Ultra-high input impedance low noise integrated amplifier for noncontact biopotential sensing. IEEE Trans Emerg Sel Topics Circ Syst 1(4):526–535 Chi Y, Maier C, Cauwenberghs G (2011) Ultra-high input impedance low noise integrated amplifier for noncontact biopotential sensing. IEEE Trans Emerg Sel Topics Circ Syst 1(4):526–535
Metadata
Title
A Low Power High Input Impedance CMOS Biopotential Integrated Preamplifier
Authors
Porika Nandini
Jatoth Deepak Naik
Pradeep Gorre
Alaaddin Al-Shidaifat
Mohammad Khaleqi Qaleh Jooq
Sandeep Kumar
Hanjung Song
Copyright Year
2025
Publisher
Springer Nature Singapore
DOI
https://doi.org/10.1007/978-981-97-1943-3_23