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Published in: International Journal of Computer Assisted Radiology and Surgery 4/2021

31-03-2021 | Original Article

A machine learning-based pulmonary venous obstruction prediction model using clinical data and CT image

Authors: Zeyang Yao, Xinrong Hu, Xiaobing Liu, Wen Xie, Yuhao Dong, Hailong Qiu, Zewen Chen, Yiyu Shi, Xiaowei Xu, Meiping Huang, Jian Zhuang

Published in: International Journal of Computer Assisted Radiology and Surgery | Issue 4/2021

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Abstract

Purpose

In this study, we try to consider the most common type of total anomalous pulmonary venous connection and established a machine learning-based prediction model for postoperative pulmonary venous obstruction by using clinical data and CT images jointly.

Method

Patients diagnosed with supracardiac TPAVC from January 1, 2009, to December 31, 2018, in Guangdong Province People’s Hospital were enrolled. Logistic regression were applied for clinical data features selection, while a convolutional neural network was used to extract CT images features. The prediction model was established by integrating the above two kinds of features for PVO prediction. And the proposed methods were evaluated using fourfold cross-validation.

Result

Finally, 131 patients were enrolled in our study. Results show that compared with traditional approaches, the machine learning-based joint method using clinical data and CT image achieved the highest average AUC score of 0.943. In addition, the joint method also achieved a higher sensitivity of 0.828 and a higher positive prediction value of 0.864.

Conclusion

Using clinical data and CT images jointly can improve the performance significantly compared with other methods that using only clinical data or CT images. The proposed machine learning-based joint method demonstrates the practicability of fully using multi-modality clinical data.

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Metadata
Title
A machine learning-based pulmonary venous obstruction prediction model using clinical data and CT image
Authors
Zeyang Yao
Xinrong Hu
Xiaobing Liu
Wen Xie
Yuhao Dong
Hailong Qiu
Zewen Chen
Yiyu Shi
Xiaowei Xu
Meiping Huang
Jian Zhuang
Publication date
31-03-2021
Publisher
Springer International Publishing
Published in
International Journal of Computer Assisted Radiology and Surgery / Issue 4/2021
Print ISSN: 1861-6410
Electronic ISSN: 1861-6429
DOI
https://doi.org/10.1007/s11548-021-02335-y

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