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A Novel Method for Pathogen Detection by Using Evanescent-Wave-Based Microscopy

  • 2021
  • OriginalPaper
  • Chapter
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Abstract

The chapter explores the challenge of detecting colorless pathogens like viruses and bacteria, which are invisible under conventional microscopes. It introduces the principle of Total Internal Reflection Fluorescence Microscopy (TIRF) and its application in imaging nanoscale biological specimens. The core innovation is a wearable microscopic belt that uses graphene aerogel and fluorescent light to generate evanescent waves, making pathogens visible. The device includes optical sensors and nano-projecting units to capture and display the pathogens, offering a practical solution for rapid and effective pathogen detection. Preliminary results demonstrate the device's potential, highlighting its advantages over traditional microscopes in terms of cost and portability.

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Title
A Novel Method for Pathogen Detection by Using Evanescent-Wave-Based Microscopy
Author
Vijay A. Kanade
Copyright Year
2021
Publisher
Springer Singapore
DOI
https://doi.org/10.1007/978-981-15-9509-7_42
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