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2013 | OriginalPaper | Chapter

6. Allogeneic Blood Transfusion for Surgical and Traumatic Hemorrhage

Authors : Mercy Kuriyan, Jeffrey L. Carson

Published in: Hemoglobin-Based Oxygen Carriers as Red Cell Substitutes and Oxygen Therapeutics

Publisher: Springer Berlin Heidelberg

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Abstract

Blood transfusion is an essential treatment for patients suffering blood loss associated with trauma and surgery. This chapter discusses the goal and rationale for allogeneic red cell transfusion in surgical and traumatic hemorrhage in a hospital setting. A large number of patients have now been enrolled in clinical trials. This experience provides high quality evidence to inform the transfusion decision. A restrictive transfusion has been established to be safe in adult and pediatric patients in many clinical settings. The criteria used for making the decision to transfuse and current clinical practice guidelines and evidence-based recommendations are provided.

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Blair SD, Janvrin SB, McCollum CN, Greenhalgh RM (1986) Effect of early blood transfusion on gastrointestinal haemorrhage. Br J Surg 73:783–785CrossRef

Bracey AW, Radovancevic R, Riggs SA et al (1999) Lowering the hemoglobin threshold for transfusion in coronary artery bypass procedures: effect on patient outcome. Transfusion 39:1070–1077CrossRef

Bush RL, Pevec WC, Holcroft JW (1997) A Prospective, randomized trial limiting perioperative red blood cell transfusions in vascular patients. Am J Surg 174:143–148CrossRef

Carson JLC, Carless PA, Hebert PC (2013) Outcomes using lower versus higher hemoglobin thresholds for red blood cell transfusion. JAMA

Carson JL, Carless PA, Hebert PC (2012) Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion. Cochrane Database of Syst Rev 4:CD002042

Carson JL, Duff A, Poses RM et al (1996) Effect of anaemia and cardiovascular disease on surgical mortality and morbidity. Lancet 348:1055–1060CrossRef

Carson JL, Noveck H, Berlin JA, Gould SA (2002) Mortality and morbidity in patients with very low postoperative Hb levels who decline blood transfusion. Transfusion 42:812–818CrossRef

Carson JL, Terrin ML, Noveck H et al (2011) Liberal or restrictive transfusion in high-risk patients after hip surgery. N Engl J Med 365:2453–2462CrossRef

Carson JL, Grossman BJ, Kleinman S et al (2012b) Red blood cell transfusion: a clinical practice guideline from the AABB*. Ann Intern Med 157:49–58CrossRef

Carson JL, Terrin ML, Barton FB et al (1998) A pilot randomized trial comparing symptomatic fMeta-Analysis of Clinical Trial versus hemoglobin-level-driven red blood cell transfusions following hip fracture. Transfusion 38:522–529CrossRef

Colomo A, Hernandez-Gea V, Madoz P et al (2009) Hemodynamic changes and transfusion strategies in cirrhotic patiens with acute variceal bleeding. Hepatology 50:403A

Cooper HA, Rao SV, Greenberg MD et al (2011) Conservative versus liberal red cell transfusion in acute myocardial infarction (the CRIT Randomized Pilot Study). Am J Cardiol 108:1108–1111CrossRef

Fortune JB, Feustel PJ, Saifi J, Stratton HH, Newell JC, Shah DM (1987) Influence of hematocrit on cardiopulmonary function after acute hemorrhage. J Trauma 27:243–249CrossRef

Foss NB, Kristensen MT, Jensen PS, Palm H, Krasheninnikoff M, Kehlet H (2009) The effects of liberal versus restrictive transfusion thresholds on ambulation after hip fracture surgery. Transfusion 49:227–234CrossRef

Grover M, Talwalkar S, Casbard A et al (2006) Silent myocardial ischaemia and haemoglobin concentration: a randomized controlled trial of transfusion strategy in lower limb arthroplasty. Vox Sang 90:105–112CrossRef

Hajjar LA, Vincent JL, Galas FR et al (2010) Transfusion requirements after cardiac surgery: the TRACS randomized controlled trial. JAMA 304:1559–1567CrossRef

Hebert PC, Wells G, Blajchman MA et al (1999) A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group [see comments]. N Engl J Med 340:409–417CrossRef

Hebert PC, Wells G, Marshall J et al (1995) Transfusion requirements in critical care. a pilot study. Canadian critical care trials group [published erratum appears in JAMA 1995 Sep 27;274(12):944]. Jthe Am Med Assoc 273:1439–44

Johnson RG, Thurer RL, Kruskall MS et al (1992) Comparison of two transfusion strategies after elective operations for myocardial revascularization. J Thorac Cardiovasc Surg 104:307–314

Lacroix J, Hebert PC, Hutchison JS et al (2007) Transfusion strategies for patients in pediatric intensive care units. N Engl J Med 356:1609–1619CrossRef

Leung JM, Weiskopf RB, Feiner J et al (2000) Electrocardiographic ST-segment changes during acute, severe isovolemic hemodilution in humans [In Process Citation]. Anesthesiology 93:1004–1010CrossRef

Lotke PA, Barth P, Garino JP, Cook EF (1999) Predonated autologous blood transfusions after total knee arthroplasty: immediate versus delayed administration. J Arthroplasty 14:647–650CrossRef

Mathru M, Kleinman B, Blakeman B, Dries D, Zecca A, Rao T (1991) Cardiovascular adjustments and gas exchange during extreme hemodilution in humans. Crit Care Med 19:700–704CrossRef

Middelburg RA, van de Watering LM, van der Bom JG (2010) Blood transfusions: good or bad? confounding by indication, an underestimated problem in clinical transfusion research. Transfusion 50:1181–1183CrossRef

Napolitano LM, Kurek S, Luchette FA et al (2009) Clinical practice guideline: red blood cell transfusion in adult trauma and critical care. Crit Care Med 37:3124–3157CrossRef

PROPPR—Pragmatic (2012) Randomized optimal platelet and plasma ratios. http://cetir-tmc.org/research/proppr Accessed 30 Nov 2012

Ranucci M, Di Dedda U, Castelvecchio S et al (2012) Impact of preoperative anemia on outcome in adult cardiac surgery: a propensity-matched analysis. Ann Thorac Surg 94:1134–1141CrossRef

Repine TB, Perkins JG, Kauvar DS, Blackborne L (2006) The use of fresh whole blood in massive transfusion. J Trauma 60:S59–S69CrossRef

Shehata N, Burns LA, Nathan H et al (2012) A randomized controlled pilot study of adherence to transfusion strategies in cardiac surgery. Transfusion 52:91–99CrossRef

So-Osman C, Nelissen R, Te Slaa R, Coene L, Brand R, Brand A (2010) A randomized comparison of transfusion triggers in elective orthopaedic surgery using leucocyte-depleted red blood cells. Vox Sang 98:56–64CrossRef

Spinella PC, Perkins JG, Grathwohl KW, Beekley AC, Holcomb JB (2009) Warm fresh whole blood is independently associated with improved survival for patients with combat-related traumatic injuries. J Trauma 66:S69–S76CrossRef

Theusinger OM, Madjdpour C, Spahn DR (2012) Resuscitation and transfusion management in trauma patients: emerging concepts. Current Opin Crit Care 18:661–670CrossRef

Topley E, Fischer MR (1956) The illness of trauma. Br J Clin Pract 1:770–776

Tien H, Nascimento B Jr, Callum J, Rizoli S (2007) An approach to transfusion and hemorrhage in trauma: current perspectives on restrictive transfusion strategies. Can J surg J canadien de chirurgie 50:202–209

Villanueva C, Colomo A, Bosch A et al (2013) Transfusion strategies for acute upper gastrointestinal bleeding. N Engl J Med 368:11–21

Weiskopf RB, Viele MK, Feiner J et al (1998) Human cardiovascular and metabolic response to acute, severe isovolemic anemia. J Am Med Assoc 279:217–221CrossRef

Weiskopf RB, Kramer JH, DP et al (2000) Acute severe isovolemic anemia impairs cognitive function and memory in humans. Anesthesiology 92:1646–52

Wu WC, Schifftner TL, Henderson WG et al (2007) Preoperative hematocrit levels and postoperative outcomes in older patients undergoing noncardiac surgery. JAMA 297:2481–2488CrossRef

Title: Allogeneic Blood Transfusion for Surgical and Traumatic Hemorrhage
Authors: Mercy Kuriyan
Jeffrey L. Carson
Publisher: Springer Berlin Heidelberg
Book: Hemoglobin-Based Oxygen Carriers as Red Cell Substitutes and Oxygen Therapeutics
Print ISBN: 978-3-642-40716-1

Electronic ISBN: 978-3-642-40717-8

Copyright Year: 2013
DOI: https://doi.org/10.1007/978-3-642-40717-8_6

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