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Published in: Journal of Scientific Computing 1/2017

28-09-2016

An Approximation of the \(M_2\) Closure: Application to Radiotherapy Dose Simulation

Authors: T. Pichard, G. W. Alldredge, S. Brull, B. Dubroca, M. Frank

Published in: Journal of Scientific Computing | Issue 1/2017

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Abstract

Particle transport in radiation therapy can be modelled by a kinetic equation which must be solved numerically. Unfortunately, the numerical solution of such equations is generally too expensive for applications in medical centers. Moment methods provide a hierarchy of models used to reduce the numerical cost of these simulations while preserving basic properties of the solutions. Moment models require a closure because they have more unknowns than equations. The entropy-based closure is based on the physical description of the particle interactions and provides desirable properties. However, computing this closure is expensive. We propose an approximation of the closure for the first two models in the hierarchy, the \(M_1\) and \(M_2\) models valid in one, two or three dimensions of space. Compared to other approximate closures, our method works in multiple dimensions. We obtain the approximation by a careful study of the domain of realizability and by invariance properties of the entropy minimizer. The \(M_2\) model is shown to provide significantly better accuracy than the \(M_1\) model for the numerical simulation of a dose computation in radiotherapy. We propose a numerical solver using those approximated closures. Numerical experiments in dose computation test cases show that the new method is more efficient compared to numerical solution of the minimum entropy problem using standard software tools.

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Appendix
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Metadata
Title
An Approximation of the Closure: Application to Radiotherapy Dose Simulation
Authors
T. Pichard
G. W. Alldredge
S. Brull
B. Dubroca
M. Frank
Publication date
28-09-2016
Publisher
Springer US
Published in
Journal of Scientific Computing / Issue 1/2017
Print ISSN: 0885-7474
Electronic ISSN: 1573-7691
DOI
https://doi.org/10.1007/s10915-016-0292-8

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