2011 | OriginalPaper | Chapter
Beat-by-Beat Variability of QT ECG-Interval Holds a Well-Founded Promise for Clinical Cardiology: A Review
Author : R. Negoescu
Published in: International Conference on Advancements of Medicine and Health Care through Technology
Publisher: Springer Berlin Heidelberg
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The advent of reliable software access to beat-by-beat QT interval series opened a novel insight to sympathetic control of ventricular myocardium.
Experimental measurement of time constant in the RR-QT system (
τ
QT
) using pharmacological or electrophysiological manipulations of heart rate (HR) has documented that
τ
QT
size may introduce in borderline subjects in normal life settings episodes of functional long-QT syndrome.
In type I young diabetics in the earliest phase of autonomic dysfunction, spectral QT and RR analyses suggest preferential vagal down-regulation but preservation of sympathetic responsiveness of ventricles to life challenges.
Both findings signal an early risk worth to be dealt with by specific preventive steps.