6. Biofunctionalization and Surface Chemistry

This chapter delves into the intricate world of biofunctionalization, focusing on the immobilization of biomolecules onto solid supports. It explores various covalent and non-covalent coupling strategies, such as carbodiimide and glutaraldehyde coupling, highlighting their efficiency and stability. The text also discusses the importance of surface chemistry in fields like heterogeneous biocatalysis and biosensors, providing a summary of main surface modification strategies. Additionally, it covers the specifics of nanomaterials biofunctionalization, emphasizing their unique properties and potential in electronic and optical signal transduction. The chapter concludes with an overview of the applications of biofunctionalized nanomaterials in biosensing and bioanalysis, offering insights into their remarkable selectivity and reproducibility. Readers will gain a comprehensive understanding of the methods and principles behind biofunctionalization, making this chapter an essential read for those interested in advancing their knowledge in this cutting-edge field.