Using Biocompatible Hot-Melt Adhesives to Close Large Wounds
In most cases, large open wounds are still closed using stitches or staples. Researchers at the Technion – Israel Institute of Technology have developed a medical hot-melt adhesive system for sealing these types of wounds in the future. It will also speed up the healing process.
The system comprises a type of glue gun and a skin-friendly hot-melt adhesive. The adhesive has been developed such that it stays flexible while the wound is healing and decomposes within a few weeks without leaving a residue.
The innovative adhesive – a biocompatible, biodegradable and elastic polymer based on polycaprolactone – melts at temperatures just above body temperature, meaning it can be handled without the risk of burns. In order to achieve the desired mechanical properties, durability and tissue compatibility, scientists experimented with the physical structure but left the chemical characteristics unchanged.
Speeding up the healing process
The polymer melts at minimal pressure and can be applied directly onto the wound using a special medical glue gun. It hardens quickly, binding itself firmly to the edges of the wound. Remarkably, the glued tissue remains flexible throughout the entire healing process. After a few weeks, the biocompatible adhesive completely decomposes. In addition, the material is said to be four times as strong as existing wound adhesives.
The biocompatibility of the adhesive procedure has already been confirmed in relevant laboratory tests. In the future, this should lead to a reduction in the use of staples and needles, a faster healing process and smaller scars.