2010 | OriginalPaper | Chapter
Bone Remodelling: A Complex Automata-Based Model Running in BioShape
Authors : Diletta Cacciagrano, Flavio Corradini, Emanuela Merelli
Published in: Cellular Automata
Publisher: Springer Berlin Heidelberg
Activate our intelligent search to find suitable subject content or patents.
Select sections of text to find matching patents with Artificial Intelligence. powered by
Select sections of text to find additional relevant content using AI-assisted search. powered by
Bone remodelling, as many biological phenomena, is inherently multi-scale, i.e. it is characterised by interactions involving different scales at the same time. At this aim, we exploit the
Complex Automata
paradigm and the
BioShape
3D spatial simulator respectively (i) for describing the bone remodelling process in terms of a 2-scale aggregation of
uniform
Cellular Automata
coupled by a
well-established
composition pattern, and (ii) for executing them in a
uniform
and integrated way in terms of shapes equipped with perception and movement capabilities.
On the one hand, the proposed model confirms the high expressiveness degree of Complex Automata to describe multi-scale phenomena. On the other hand, the possibility of executing such a model in
BioShape
highlights the existence of a general mapping - from Complex Automata into the
BioShape
native modelling paradigm - also enforced by the fact that both approaches result to be suitable for handling different scales in a uniform way, for including spatial information and for bypassing inter-scale homogenization problems.