01-07-2022 | Research paper
Carbon dots and gold nanocluster–based hybrid microgels and their application in cells imaging
Longping Zhou, Bo Liao, Shilin Yang, Shoujun Yi
Journal of Nanoparticle Research
Login to get access
The hybrid microgels of carbon dots (CDs) and gold nanoclusters (AuNCs) have been prepared with precipitation polymerization. This hybrid microgels exhibited dual emissions thanks to organic integration of CDs and AuNCs for their unique fluorescence properties maintained in the microgel system. The fluorescence intensity ratio at 570 nm and 450 nm of the dual-emitting has a good linear response to temperature varying at the range of 20–50 °C. In addition, the ratio of the dual emissions intensity of the hybrid microgel shows well linear relationship at pH range between 9.0 and 11.0, which promises to be used as pH sensor. Furthermore, this hybrid microgel is inherently non-cytotoxic, which could be used as high efficient fluorescent probes in living cell with dual colors. Thus, this novel dual-emission hybrid microgel system can be used not only as a multifunctional sensor, but also to expand potential applications in biomedical engineering.