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Cell-Free Based Protein Array Technology

  • 2021
  • OriginalPaper
  • Chapter
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Abstract

The chapter delves into the significance of protein-protein interactomes in understanding biological functions and drug development. It introduces Cell-Free Based Protein Array Technology, highlighting its advantages over traditional methods. The technology enables high-throughput production of proteins and the identification of interacting proteins, such as E3 ubiquitin ligases. The chapter also showcases the application of this technology in antibody validation, providing a robust platform for screening cross-reactive antigens. The detailed exploration of these topics underscores the potential of cell-free protein array technology in advancing life science research and drug discovery.

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Title
Cell-Free Based Protein Array Technology
Authors
Ryo Morishita
Hirotaka Takahashi
Tatsuya Sawasaki
Copyright Year
2021
Publisher
Springer Singapore
DOI
https://doi.org/10.1007/978-981-16-4866-3_18
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