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Published in: Cellulose 15/2020

04-08-2020 | Original Research

Cellulose nanofibers electrospun from aqueous conditions

Authors: Hui Zhang, Yan Liu, Sisi Cui, Yifa Zhou, Junli Hu, Jiangang Ma, Yichun Liu

Published in: Cellulose | Issue 15/2020

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Abstract

Electrospun cellulose nanofibers are promising biomaterials but are suffering from the use of unfavorable organic solvents during the electrospinning process. In this manuscript, we used the periodate oxidation—adipic acid dihydrazide crosslinking strategy to fabricate electrospun cellulose nanofibers. Periodate oxidation of cellulose generated water soluble aldehyde cellulose, which thus allowed for the electrospinning in aqueous solution and avoided the use of unfavorable organic solvents. The following crosslinking with adipic acid dihydrazide made the nanofibers water resistant. The results show that the prepared cellulose nanofiber mats show moderate wet mechanical strength around 1 MPa, are able to absorb water equal to 30 times of their own weight, can degrade gradually by hydrolysis, and are cytocompatible. These cellulose nanofibers are expected to find applications in biomedical fields such as wound healing and tissue regeneration.

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Literature
go back to reference Gabriel A, Barrett C, Cullen B et al (2020) Infection and inflammation in the wound environment: addressing issues of delayed wound healing with advanced wound dressings. Wounds 32:S1–S17PubMed Gabriel A, Barrett C, Cullen B et al (2020) Infection and inflammation in the wound environment: addressing issues of delayed wound healing with advanced wound dressings. Wounds 32:S1–S17PubMed
go back to reference Khan TA, Peh KK, Ch'ng HS (2000) Mechanical, bioadhesive strength and biological evaluations of chitosan films for wound dressing. J Pharm Pharm Sci 3:303–311PubMed Khan TA, Peh KK, Ch'ng HS (2000) Mechanical, bioadhesive strength and biological evaluations of chitosan films for wound dressing. J Pharm Pharm Sci 3:303–311PubMed
Metadata
Title
Cellulose nanofibers electrospun from aqueous conditions
Authors
Hui Zhang
Yan Liu
Sisi Cui
Yifa Zhou
Junli Hu
Jiangang Ma
Yichun Liu
Publication date
04-08-2020
Publisher
Springer Netherlands
Published in
Cellulose / Issue 15/2020
Print ISSN: 0969-0239
Electronic ISSN: 1572-882X
DOI
https://doi.org/10.1007/s10570-020-03366-5

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