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A Human-Centered Behavioral Informatics Read chapter Read first chapter

2019 | OriginalPaper | Chapter

12. Consciousness and the Archipelago of Functional Integration: On the Relation Between the Midbrain and the Ascending Reticular Activating System

Authors : Nelson Mauro Maldonato, Anna Esposito, Silvia Dell’Orco

Published in: Quantifying and Processing Biomedical and Behavioral Signals

Publisher: Springer International Publishing

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Abstract

Historically, the relation between consciousness and the brainstem has been demonstrated, on the one hand, by injuries to the upper brainstem that lead to minimum states of consciousness, comas and persistent vegetative states and, on the other hand, by electrophyisiological recordings that link the ascending reticular activating system (ARAS) with vigilance and attention, functions which are necessary for interpersonal relationships. With the advances made in the clarification of the connections between the brainstem and other regions of the brain there has been no corresponding conceptual revision of the functional context within which the ARAS performs its role of activation and way in which it activates the cerebral cortex, unlike other structures of the brain. In this paper we shall discuss the way in which the brainstem—(a) fundamental terminal of multiple ascending neural pathways—influences and modulates cortical activities; (b) the context of which the ARAS is a fundamental part—the centroencephalic archipelago of functional integration—for the transmission of contents to specific regions that generate the sensation of subjectivity.

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Literature
1.
Maldonato, N.M.: From neuron to consciousness: for an experience-based neuroscience. World Futures 65(2), 80–93 (2009)CrossRef
2.
Maldonato N. M. Embodied Consciousness. World Futures, Special Issue, 2(65) (2009)CrossRef
3.
Koch, C.: The Quest for Consciousness: A Neurobiological Approach. Roberts and Company Publishers, Englewood, CO (2004)
4.
Penfield, W.: The Mystery of the Mind: A Critical Study of Consciousness and the Human Brain. Princeton, Princeton University Press (1975)
5.
Goldberg, M.E.: The control of gaze. In: Kandel, E.R., Schwartz, J.H., Jessel, J.H. (eds.) Principles of Neuroscience, 4th edn, pp. 782–800. McGraw Hill, New York (2000)
6.
McNarry, A.F., Goldhill, D.R.: Simple bedside assessment of level of consciousness: comparison of two simple assessment scales with the Glasgow Coma scale. Anaesthesia 59, 34–37 (2004)CrossRef
7.
Parvizi, J., Damasio, A.R.: Neuroanatomical correlates of brainstem coma. Brain 126, 1524–1536 (2003)CrossRef
8.
Moruzzi, G., Magoun, H.W.: Brain stem reticular formation and activation of the EEG. Electroencephalogr. Clin. Neurophysiol. 1, 455–473 (1949)CrossRef
9.
Magoun, H.W.: An ascending reticular activating system in the brain stem. Arch. Neurol. Psychiatry 67(2), 145–154 (1952)CrossRef
10.
Batini, C., Moruzzi, G., Palestino, M., Rossi, G.F., Zanchetti, A.: Persistent patterns of wakefulness in the pretrigeminal midpontine preparation. Science 128, 30 (1958)CrossRef
11.
Mai, J., Paxinos, G.: The Human Nervous System. Elsevier, Amsterdam (2011)
12.
Kandel, E.R., Schwartz, J.H., Jessell, T.M., Siegelbaum, S.A., Hudspeth, A.J.: Principles of Neural Science. McGraw-Hill, New York (2012)
13.
Posner, J.B., Clifford, B.S., Schiff, N.D., Plum, F.: Plum and Posner’s Diagnosis of Stupor and Coma, 4th edn. Oxford University Press, New York (2007)
14.
Laureys, S., Gosseries, O., Tononi, G. (eds.): The Neurology of Consciousness: Cognitive Science and Neuropathology, 2nd edn. Waltham, MA, New York (2016)
15.
Bloom, F.E.: What is the role of general activating systems in cortical function? In: Rakic, P., Singer, W. (eds.) Neurobiology of Neocortex, pp. 407–421. Wiley, New York (1997)
16.
Hirata, A., Castro-Alamancos, M.A.: Neocortex network activation and deactivation states controlled by the thalamus. J. Neurophysiol. 103, 1147–1157 (2010)CrossRef
17.
Damasio, A.R., Grabowski, T.J., Bechara, A., Damasio, H., Ponto, L.L., Parvizi, J., Hichwa, R.D.: Distinctive patterns of subcortical and cortical brain activation associated with self-generated emotions and feelings. Nat. Neurosci. 3(10), 1049–1056 (2000)CrossRef
18.
Llinas, R., Ribury, U., Contreras, D., Pedroarena, C.: The neuronal basis of consciousness. Philos. Trans. R. Soc. Lond. B Biol. Sci. 353, 1841–1849 (1998)CrossRef
19.
Dehaene, S., Changeux, J.P.: Neural mechanisms for access to consciousness. In: Gazanniga, M.S. (ed.) The Cognitive Neurosciences, pp. 1145–1147. Norton, New York (2004)
20.
Crick, F.: Function of the thalamic reticular complex: The searchlight hypothesis. Proc. Natl. Acad. Sci. U.S.A. 81, 4586–4590 (1984)CrossRef
21.
Koyama, T., McHaffie, J.G., Luarienti, P.J., Coghill, R.C.: The subjective experience of pain: Where expectations become reality. Proc. Natl. Acad. Sci. U.S.A. 102, 12950–12955 (2005)CrossRef
22.
Steriade, M.: Neuromodulatory Systems of Thalamus and Neocortex. Semi. Neurosci. 7(5), 361–370 (1995)CrossRef
23.
Hirata, A., Castro-Alamancos, M.A.: Neocortex network activation and deactivation states controlled by the thalamus. J. Neurophysiol. 103, 1147–1157 (2010)CrossRef
24.
Harris, K.D., Thiele, A.: Cortical state and attention. Nat. Rev. Neurosci. 12, 509–523 (2011)CrossRef
25.
Maldonato, N.M.: The Ascending Reticular Activating System. The Common Root of Consciousness and Attention, vol. 26, pp. 333–344. Springer, Berlin (2014)
26.
Rigas, P., Castro-Alamancos, M.A.: Thalamocortical up states: differential effects of intrinsic and extrinsic cortical inputs on persistent activity. J. Neurosci. 27, 4261–4272 (2007)CrossRef
27.
Penfield, W.: Lights in the great darkness. Harvey cushing oration. J. Neurosurg. 35, 377–383 (1971)CrossRef
28.
Penfield, W.: Some observations on the cerebral cortex of man. In: Proceedings of the Royal Society of London. Series B, Biological Sciences, vol. 134, pp. 329–47 (1947)
29.
Yeo, S.S., Chang, P.H., Jang, S.H.: The ascending reticular activating system from pontine reticular formation to the thalamus in the human brain. Front Hum Neurosci 7, 416 (2013)CrossRef
30.
Maldonato, N.M., Dell’Orco, S., Springer, M.: Rethinking consciousness: some hypothesis on the role of the ascending reticular activating system in global workspace. In: Apolloni, B. (ed.) Neural Nets WIRN11. IOS Press, Amsterdam (2011)
31.
Damasio, A.R., Grabowski, T.J., Bechara, A., Damasio, H., Ponto, L.L., Parvizi, J., Hichwa, R.D.: Distinctive patterns of subcortical and cortical brain activation associated with self-generated emotions and feelings. Nat. Neurosci. 3(10), 1049–1056 (2000)CrossRef
32.
Oliverio, A., Maldonato, N.M.: The creative brain. In: CogInfoCom, 5th IEEE International Conference on Cognitive Infocommunications, November 5–7, pp. 527–532 (2014)
33.
Maldonato, N.M.: From Neuron to Consciousness: For an Experience-Based Neuroscience. World Futures 65(2), 80–93 (2009)CrossRef
34.
Kocsis, B., Varga, V., Dahan, L., Sik, A.: Serotonergic neuron diversity: identification of raphe neurons with discharges time-locked to the hippocampal theta rhythm. Proc. Natl. Acad. Sci. U.S.A. 103, 1059–1064 (2006)CrossRef
35.
Grzanna, R., Molliver, M.E.: Cytoarchitecture and dendritic morphology of central noradrenergic neurons. In: Hobson, J.A., Brazier, M.A.B. (eds.) The Reticular Formation Revisited: Specifying Function for a Nonspecific System, pp. 83–97. Raven Press, New York (1980)
36.
Monti, J.M., Jantos, H.C.: The roles of dopamine and serotonin, and of their receptors, in regulating sleep and waking. Prog. Brain Res. 172, 625–646 (2008)CrossRef
37.
Parvizi, J., Damasio, A.: Consciousness and the brainstem. Cognition 79, 135–160 (2001)CrossRef
38.
Maldonato, N.M., Oliverio, A., Esposito, A.: Neuronal symphonies: musical improvisation and the centrencephalic space of functional integration. World Futures 73, 1–20 (2017)CrossRef
39.
Damasio, A., Carvalho, G.B.: The nature of feelings: Evolutionary and neurobiological origins. Nat. Rev. Neurosci. 14(2), 143–152 (2013)CrossRef
40.
Zeki, S., Bartels, A.: The asynchrony of consciousness. Proc. Roy. Soc. London 265, 1583–1585 (1998)CrossRef
41.
Libet, B.: Mind Time. Harvard University Press, Cambridge Mass (2004)
42.
Haggard, P., Clark, S., Kalogeras, J.: Voluntary action and conscious awareness. Nat. Neurosci. 5(4), 382–385 (2002)CrossRef
43.
Berlucchi, G., Aglioti, S.M.: The body in the brain. Exp. Brain Res. 200, 25–35 (2010)CrossRef
44.
Ey, H.: Conscioussnes: A Phenomenological Study of Being Conscious and Becoming Conscious. Indiana University Press, Bloomington (1978)
45.
Changeux, J.P.: Conscious processing: implications for general anesthesia. Curr Opin Anaesthesiol. 25, 397–404 (2012)CrossRef
46.
Mashour, G.A., Alkire, M.T.: Evolution of consciousness: phylogeny, ontogeny, and emergence from general anesthesia. Proc. Natl. Acad. Sci. U.S.A. 110(Suppl. 2), 10357–10364 (2013)CrossRef
47.
Posner, J.B., Clifford, B.S., Schiff, N.D., Plum, F.: Plum and Posner’s Diagnosis of Stupor and Coma, 4th edn. Oxford University Press, New York (2007)
48.
Sanders, R.D., Tononi, G., Laureys, S., Sleigh, J.: Unresponsiveness not equal Unconsciousness. Anesthesiology 116, 946–959 (2012)CrossRef
49.
Långsjö, J.W., Alkire, M.T., Kaskinoro, K., Hayama, H., Maksimow, A., Kaisti, K.K., Aalto, S., Aantaa, R., Jääskeläinen, S.K., Revonsuo, A., Scheinin, H.: Returning from Oblivion: Imaging the neural core of consciousness. J. Neurosci. 32(14), 4935–4943 (2012)CrossRef
50.
Guldenmund, P., Vanhaudenhuyse, A., Boly, M., Laureys, S., Soddu, A.: A default mode of brain function in altered states of consciousness. Arch. Ital. Biol. 150(2–3), 107–121 (2012)
51.
Boly, M., Phillips, C., Tshibanda, L., Vanhaudenhuyse, A., Schabus, M., Dang-Vu, T.T., et al.: Intrinsic brain activity in altered states of consciousness: how conscious is the default mode of brain function? Ann NY Acad Sci 1129, 119–129 (2008)CrossRef
52.
Maldonato, N.M., Anzoise, A.: Homo-Machina Visual Metaphors. Representations of Consciousness and Scientific thinking, pp. 437–451. Springer, Berlin, Heidelberg (2013)
53.
Maldonato, N.M., Valerio, P.: Artificial entities or moral agents? How AI is changing human evolution. In: Esposito, A., Faundez-Zanuy, M., Morabito, F.C., Pasero, E. (eds.) Multidisciplinary Approaches to Neural Computing. Series: Smart Innovation, Systems and Technologies, vol. 69. Springer, Berlin (2017)
Metadata
Title
Consciousness and the Archipelago of Functional Integration: On the Relation Between the Midbrain and the Ascending Reticular Activating System
Authors
Nelson Mauro Maldonato
Anna Esposito
Silvia Dell’Orco
Copyright Year
2019
Book
Quantifying and Processing Biomedical and Behavioral Signals

Print ISBN: 978-3-319-95094-5

Electronic ISBN: 978-3-319-95095-2

Copyright Year: 2019

DOI
https://doi.org/10.1007/978-3-319-95095-2_12

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