Skip to main content
Top
Published in:

01-02-2025

Design and optimization of a terahertz photonic crystal fiber based biosensor to detect malaria disease

Authors: Vishal Chaudhary, Sonal Singh

Published in: Journal of Computational Electronics | Issue 1/2025

Log in

Activate our intelligent search to find suitable subject content or patents.

search-config
loading …

Abstract

This study introduces a dual core photonic crystal fiber (DC-PCF) based biosensing approach for early detection of malaria in individuals by monitoring the variations in the red blood cells (RBCs). The proposed DC-PCF comprises four layers of a hexagonal lattice with circular air holes. In the proposed DC-PCF, we have used a central elliptical hole to infiltrate RBCs samples. The proposed study helps to detect various stages of malaria, such as infected RBCs, including the Ring stage, Trophozoite stage, and Schizont stage, by analyzing the changes in the peak wavelength. The proposed refractive index (RI) based sensor is designed to operate within an RI range of 1.33 to 1.41, enabling the detection of malaria. The numerical analysis indicate that our biosensor demonstrates significant sensitivity across different stages, such as 12,00000 nm/RIU for the ring stage, 11,15,263.15 nm/RIU for the trophozoite stage, and 11,13,793.10 nm/RIU for the schizont stage under x-polarization. Similarly, under y-polarization, the sensitivity is observed to be 10,50,000 nm/RIU for the ring stage, 10,54,736.84 nm/RIU for the trophozoite stage, and 10,32,758.62 nm/RIU for the schizont stage. The proposed DC-PCF-based biosensor is highly suitable for biological analysis and early malaria detection because it has a low detection limit and superior sensing performance.

Dont have a licence yet? Then find out more about our products and how to get one now:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

  • über 102.000 Bücher
  • über 537 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Maschinenbau + Werkstoffe
  • Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 390 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Maschinenbau + Werkstoffe




 

Jetzt Wissensvorsprung sichern!

Springer Professional "Wirtschaft"

Online-Abonnement

Mit Springer Professional "Wirtschaft" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 340 Zeitschriften

aus folgenden Fachgebieten:

  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Versicherung + Risiko




Jetzt Wissensvorsprung sichern!

Literature
14.
go back to reference Poonam, S., Preeta, S.: Design of photonic crystal-based biosensor for detection of glucose concentration in urine. IEEE Sens. J. 15, 1035–1042 (2015)CrossRefMATH Poonam, S., Preeta, S.: Design of photonic crystal-based biosensor for detection of glucose concentration in urine. IEEE Sens. J. 15, 1035–1042 (2015)CrossRefMATH
20.
go back to reference Liu, P.Y., Chin, L.K., Ser, W., Chen, H.F., Hsieh, C.M., Lee, C.H., Sung, K.B., Ayi, T.C., Yap, P.H., Liedberg, B., Wang, K., Bourouina, T., Leprince-Wang, Y.: Cell refractive index for cell biology and disease diagnosis: past, present and future. Lab Chip 16, 634–644 (2016). https://doi.org/10.1039/c5lc01445jCrossRef Liu, P.Y., Chin, L.K., Ser, W., Chen, H.F., Hsieh, C.M., Lee, C.H., Sung, K.B., Ayi, T.C., Yap, P.H., Liedberg, B., Wang, K., Bourouina, T., Leprince-Wang, Y.: Cell refractive index for cell biology and disease diagnosis: past, present and future. Lab Chip 16, 634–644 (2016). https://​doi.​org/​10.​1039/​c5lc01445jCrossRef
21.
Metadata
Title
Design and optimization of a terahertz photonic crystal fiber based biosensor to detect malaria disease
Authors
Vishal Chaudhary
Sonal Singh
Publication date
01-02-2025
Publisher
Springer US
Published in
Journal of Computational Electronics / Issue 1/2025
Print ISSN: 1569-8025
Electronic ISSN: 1572-8137
DOI
https://doi.org/10.1007/s10825-024-02255-5