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Integrable Sensor System for Live Monitoring of Loudspeaker Performances Read chapter Read first chapter

2018 | OriginalPaper | Chapter

Detection of Tumor Markers and Cell Metabolites in Cell Cultures, Using Nanostructured Chemoresistive Sensors

Authors : N. Landini, B. Fabbri, A. Gaiardo, S. Gherardi, V. Guidi, G. Rispoli, M. Valt, G. Zonta, C. Malagù

Published in: Sensors and Microsystems

Publisher: Springer International Publishing

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Abstract

Nowadays, tumor markers detection is one of the most dynamic field of research for medical technologies, as it seems a reliable source of screening technologies able to both detect neoplasms before their degeneration into malignant forms, and monitor possible relapses after the main cancer removal. On the other hand, studying neoplastic cell cultures behaviour, and their vitality in real time, places problems given to the high proliferation rate of the tumor cells. In this work, nanostructured chemoresistive sensors, sensing unit able to detect volatile chemicals in concentrations up to part per billions, have been used to detect neoplastic markers, with the idea to develop a technology able to follow in real time cell cultures and neoplasms growth, for both research and application in the medical field.

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Literature
1.
Peng, G., Hakim, M., Broza, Y.Y., Billan, S., Abdah-Bortnyak, R., Kuten, A., Tish, U., Haick, H.: Detection of lung, breast, colorectal, and prostate cancers from exhaled breath using a single array of nanosensors. Brit. J. Cancer 103, 542–551 (2010)CrossRef
2.
Altomare, D.F., Di Lena, M., Porcelli, F., Trizio, L., Travaglio, E., Tutino, M., Dragonieri, S., Memeo, V., de Gennaro, G.: Exhaled volatile organic compounds identify patients with colorectal cancer. Brit. J. Surg. 100, 144–150 (2013)CrossRef
3.
Cairns, R.A., Harris, I.S., Mak, T.W.: Regulation of cancer cell metabolism. Nat. Rev. Cancer 11, 85–95 (2011)CrossRef
4.
Qiu, Y., Cai, G., Su, M., Chen, T., Zheng, X., Xu, Y., et al.: Serum metabolite profiling of human colorectal cancer using GC—TOFMS and UPLC—QTOFMS. J. Proteome Res. 8(10), 4844–4850 (2009)CrossRef
5.
Chan, E.C.Y., Koh, P.K., Mal, M., Cheah, P.Y., Eu, K.W., Backshall, A., et al.: Metabolic profiling of human colorectal cancer using high-resolution magic angle spinning nuclear magnetic resonance (HR-MAS NMR) spectroscopy and gas chromatography mass spectrometry (GC/MS). J. Proteome Res. 8(1), 352–361 (2009)CrossRef
6.
Phillips, M., Gleeson, K., Hughes, J.M.B., Greenberg, J., Cataneo, R.N., Baker, L., et al.: Volatile organic compounds in breath as markers of lung cancer: a cross-sectional study. Lancet 353(9168), 1930–1933 (1999)CrossRef
7.
Probert, C.S.J., Ahmed, I., Khalid, T., Johnson, E., Smith, S., Ratcliffe, N.: Volatile organic compounds as diagnostic biomarkers in gastrointestinal and liver diseases. J. Gastrointestin. Liver Dis. 8(3), 337–343 (2009)
8.
Zonta, G., Anania, G., Fabbri, B., Gaiardo, A., Gherardi, S., Giberti, A., Guidi, V., Landini, N., Malagù, C.: Detection of colorectal cancer biomarkers in the presence of interfering gases. Sens. Actuators B Chem. 218, 289–295 (2015)CrossRef
9.
Malagù, C., Fabbri, B., Gherardi, S., Giberti, A., Guidi, V., Landini, N., Zonta, G.: Chemoresistive Gas Sensors for the Detection of Colorectal Cancer Biomarkers. Sensors 14(10), 18982–18992 (2014)CrossRef
10.
Landini, N., Zonta, G., Malagù, C.: Detection of tumor markers on feces with nanostructured sensors. Scholar’s Press (2015)
11.
Zonta, G., Anania, G., Fabbri, B., Gaiardo, A., Gherardi, S., Giberti, A., Landini, N., Malagù, C., Scagliarini, L., Guidi, V.: Preventive screening of colorectal cancer with a device based on chemoresistive sensors. Sens. Actuators B Chem. 238, 1098–1101 (2017)CrossRef
12.
Carotta, M.C., Martinelli, G., Sadaoka, Y., Nunziante, P., Traversa, E.: Gas-sensitive electrical properties of perovskite-type SmFeO3 thick films. Sens. Actuators B Chem. 48(1–3), 270–276 (1998)CrossRef
13.
Carotta, M.C., Ferroni, M., Gnani, D., Guidi, V., Merli, M., Martinelli, G., et al.: Nanostructured pure and Nb-doped TiO2as thick film gas sensors for environmental monitoring. Sens. Actuators B Chem. 58(1–3), 310–317 (1999)CrossRef
14.
Carotta, M.C., Benetti, M., Guidi, V., Gherardi, S., Malagù, C., Vendemiati, B., et al.: Nanostructured (Sn, Ti, Nb)O2 solid solutions for hydrogen sensing. Proc. Mater. Res. Societ. 915, 68210 (2000)
15.
Carotta, M.C., Gherardi, S., Guidi, V., Malagù, C., Martinelli, G., Vendemiati, B., et al.: (Ti, Sn)O2 binary solid solutions for gas sensing: Spectroscopic, optical and transport properties. Sens. Actuators B Chem. 130(1), 38–45 (2008)CrossRef
16.
Carotta, M.C., Cervi, A., Giberti, A., Guidi, V., Malagù, C., Martinelli, G., et al.: Metal–oxide solid solutions for light alkane sensing. Sens. Actuators B Chem. 133(2), 516–520 (2008)CrossRef
17.
Carotta, M.C., Cervi, A., di Natale, V., Gherardi, S., Giberti, A., Guidi, V., et al.: ZnO gas sensors: a comparison between nanoparticles and nanotetrapods-based thick films. Sens. Actuators B Chem. 137(1), 164–169 (2009)CrossRef
18.
Carotta, M.C., Guidi, V., Malagù, C., Vendemiati, B., Zanni, A., Martinelli, G., et al.: Vanadium and tantalum-doped titanium oxide (TiTaV): a novel material for gas sensing. Sens. Actuators B Chem. 108(1–2), 89–96 (2005)CrossRef
19.
Guidi, V., Malagù, C., Carotta, M.C., Vendemiati, B.: Printed films: Materials science and applications in sensors, electronics and photonics. Woodhead Publ. Ser. Electron. Opt. Mater. 278–334 (2012)
20.
Gaiardo, A., Fabbri, B., Guidi, V., Bellutti, P., Giberti, A., Gherardi, S., et al.: Metal sulfides as sensing materials for chemoresistive gas sensors. Sensors 16(3), 296 (2016)CrossRef
21.
Landini, N., Zonta, G., Malagù, C.: Detection of tumor markers on feces with nanostructured sensors. Scholar’s Press (2015)
22.
SCENT B1, patent number: 102015000057717, property of SCENT S.r.l
Metadata
Title
Detection of Tumor Markers and Cell Metabolites in Cell Cultures, Using Nanostructured Chemoresistive Sensors
Authors
N. Landini
B. Fabbri
A. Gaiardo
S. Gherardi
V. Guidi
G. Rispoli
M. Valt
G. Zonta
C. Malagù
Copyright Year
2018
Book
Sensors and Microsystems

Print ISBN: 978-3-319-66801-7

Electronic ISBN: 978-3-319-66802-4

Copyright Year: 2018

DOI
https://doi.org/10.1007/978-3-319-66802-4_8