Development of a noninvasive glucose measurement system based on orthogonal twin polarized lights and its primary experimental investigation

In this paper, a highly sensitive optical polarimetric sensing system has been demonstrated using method of Orthogonal Twin Polarized Light (OTPL), which converts micro-angle rotated by optical active substance such as glucose to energy difference of OTPL By detecting the small polarization rotation of polarized laser light passing through a glucosecontaining fluid, this sensing system is suitable for noninvasive glucose monitoring for diabetes patients. A resolution glucose level of 40 mg/dl has been obtained, with a 0.9777 correlation coefficient between the glucose concentration and the measured values. The advantages of this system are that it can make use of visible light, reducing influence of phase significantly, easily available and it can be easily miniaturized.